Malaria Vaccine May Not Eliminate Need to Combat Counterfeit Medicines
The newly announced malaria vaccine could be a critical tool to combat the tremendous socioeconomic burden malaria causes. But global achievements in reducing malaria cases and deaths in the past decades may be in danger of significant reversal if the problem of counterfeiting continues. (Source: The RAND Blog)
Source: The RAND Blog - November 8, 2021 Category: Health Management Authors: Samantha McBirney; Krishna B. Kumar; Todd A. Richmond Source Type: blogs

Cool Images: Spooky and Spectacular
It’s the spookiest time of the year! To celebrate Halloween, we’re showcasing scientific images that capture the spirit of the holiday, from a brain shaped like a bat to protein “cobwebs” in a quail embryo. Check out our image and video gallery for even more scientific photos, illustrations, and videos. .featured { opacity: 1 !important; transform: scale(1) !important; z-index: 1 !important; } .featured a:hover::after { content: "Click to view on NIGMS Image Gallery"; /*Image hover tool tip*/ background-color: #fff; color: #000; text-align: center; ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - October 27, 2021 Category: Research Authors: Chrissa Chverchko Tags: Cells Cool Images Source Type: blogs

Answer to Case 658
Answer to theParasite Case of the Week 658:Trypanosoma bruceiGiven the travel history and rapid onset of symptoms,T. b. rhodesienseis the most likely parasite present. This case shows very high parasitemia with numerous trypomastigotes seen on the patient ' s thick blood film. Here is the corresponding thin blood film, highlighting some of the key diagnostic features:Note that the motile flagellate form (i.e., the trypomastigote) ofT. bruceidivides by binary fission in the peripheral blood. This is in contrast toTrypanosoma cruzi,the cause of American trypanosomiasis (a.k.a. Chagas disease), in which it is the non-motile t...
Source: Creepy Dreadful Wonderful Parasites - October 24, 2021 Category: Parasitology Source Type: blogs

Yes this is a BFD
 And it comes with a good wisecrack from Matthew Yglesias.  "Terrible news for the people of Africa, who must now face the oppression and lost liberty that comes with vaccine development. " Malaria kills more than 260,000 African children every year (I wonder if the Right to Life movement has noticed this?) and about as many adults. It also chronically debilitates many adults and does immense economic harm. Treatment resistant strains are a growing problem. The vaccine is perhaps not as highly effective as we would hopebut it makes a big difference. Strong safety profile: To date, more than 2....
Source: Stayin' Alive - October 7, 2021 Category: American Health Source Type: blogs

IBM ’ s Moonshot Ambition In Healthcare
This article is a part of our series Tech Giants In Healthcare. Previous titles included Amazon’s Dive Into Healthcare: A 2021 UpdateIs Apple Going Into Healthcare?Google’s Masterplan for HealthcareMicrosoft Makes a 16-billion Dollar Bet On Healthcare Take a deeper dive into what these companies aim for in medicine with our e-book, Tech Giants In Healthcare. Back in 2015, IBM’s previous CEO, Virginia Rometty famously said that IBM’s “moon shot will be the impact we have on healthcare.” Under the Watson Health banner, the tech company has been leveraging its expertise in cognitive computing to a...
Source: The Medical Futurist - August 9, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine Digital Health Research Future of Medicine Future of Pharma Health Sensors & Trackers Healthcare Design Personalized Medicine Portable Medical Diagnostics IBM ibm watson xprize A.I. quantum compu Source Type: blogs

Paul and the Mosquitos
From the authors of Paul Has Measles and Paul Stays Home comes Paul and the Mosquitos, an illustrated book for children about mosquito-borne diseases. (Source: virology blog)
Source: virology blog - July 30, 2021 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Chikungunya dengue fever malaria mosquito mosquito borne disease viral virus viruses yellow fever Source Type: blogs

AI-Powered App Interprets HIV Test Results
This study is a really strong partnership with AHRI that demonstrates the power of using deep learning to successfully classify ‘real-world’ field-acquired rapid test images, and reduce the number of errors that may happen when reading test results by eye,” said Rachel McKendry, a researcher involved in the study, in a UCL announcement. “This research shows the positive impact the mobile health tools can have in low- and middle-income countries, and paves the way for a larger study in the future.” Study in Nature Medicine: Deep learning of HIV field-based rapid tests Via: UCL (Source: Medgadget)
Source: Medgadget - June 22, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Informatics Medicine Public Health Source Type: blogs

Case of the Week 642
It ' s time for our monthly case from Idzi Potters and theInstitute of Tropical Medicine, Antwerp. As always, Idzi has a great case for us - courtesy of Anna Rosanas and Pieter Guetens from ITM ' s Malariology Department: a patient with extensive recent travel - leaving Belgium to trek across rural areas of Peru, Niger, Mali, and finally the Philippines. He didn ' t take any malaria prophylaxis while traveling and now presents with fever and general malaise after being home for 3 weeks. The following are thick and thin Giemsa-stained blood films from this patient (pH 8.0). The percent parasitemia was calculated at 1%. Iden...
Source: Creepy Dreadful Wonderful Parasites - June 7, 2021 Category: Parasitology Source Type: blogs

Fight Aging! Newsletter, May 17th 2021
This study is consistent with previous evidence showing that inflammaging, or age-related inflammation, is naturally heightened in the nervous system. Moreover, the authors disproved their hypothesis that anti-inflammatory microglia-specific genes are responsible for the elevated inflammatory response in aged brains since the expression of anti-inflammatory mediators was elevated in middle-aged brains following infection. Thus, the cause for the increase in pro-inflammatory genes remains to be elucidated. Mixed Results in Animal Studies of Gene Therapy Targeting Axonal Regrowth https://www.fightaging.org/archi...
Source: Fight Aging! - May 16, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Great Good of Greater Healthy Longevity
It is a strange world that we live in, in which we have to argue - actually debate with people who earnestly hold the opposing view - that more of us living for longer, in better health than is the case today, is a good outcome. That it is worth aiming for, a great good, a sign of progress, a cause worth devoting a life to. That less suffering and less death in this world of ours would be a good outcome. How is this not self-evidently true in everyone's eyes? After all, you won't find many people out there arguing for the reinstatement of the shorter, less healthy lives that our ancestors lived. Few of the world's advocate...
Source: Fight Aging! - May 10, 2021 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Sickle cell disease in newborns and children: What families should know and do
If you’ve learned that your newborn or young child has sickle cell disease, you — and other family members and friends — may have many questions. These days, most cases of sickle cell disease in the US are diagnosed through newborn screening. It’s important to make the diagnosis early, so that babies can be started on penicillin (or another antibiotic) to prevent infection. Getting connected early to a pediatrician for primary care — and to specialists in blood disorders who can work closely with the child as they grow, and with their families — can help prevent complications of the disease. The basics Hemoglob...
Source: Harvard Health Blog - May 6, 2021 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Genes Health care disparities Parenting Source Type: blogs

Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti ‐malaria Activity in Humanized Mice
Development of a Highly SelectivePlasmodium falciparum Proteasome Inhibitor with Anti ‐malaria Activity in Humanized MiceDr. Wenhu Zhan,Dr. Hao Zhang,Dr. John Ginn,Annie Leung,Yi J. Liu,Dr. Mayako Michino,Dr. Akinori Toita,Dr. Rei Okamoto,Tzu ‐Tshin Wong,Dr. Toshihiro Imaeda,Dr. Ryoma Hara,Dr. Takafumi Yukawa,Sevil Chelebieva,Patrick K. Tumwebaze,Dr. Maria Jose Lafuente ‐Monasterio,Dr. Maria Santos Martinez ‐Martinez,Dr. Jeremie Vendome,Dr. Thijs Beumin,Dr. Kenjiro Sato,Dr. Kazuyoshi Aso,Prof.  Dr. Philip J. Rosenthal,Prof.  Dr. Roland A. Cooper,Dr. Peter T. Meinke,Prof.  Dr. Carl F. Nathan,Prof.  Dr. Laura...
Source: Organometallic Current - March 11, 2021 Category: Chemistry Tags: Drug discovery Inhibitors malaria Peptide Modification Source Type: blogs

What ’s behind racial disparities in kidney disease?
My first exposure to kidney disease and its impact on communities of color occurred when I was in high school. An elderly neighbor, who was like a grandfather to me, had been diagnosed with kidney failure. At about the same time, my older first cousin, who had children about my age, was starting dialysis due to kidney failure attributed to hypertension. She would go on to get a kidney transplant. If you ask any African American, he or she is likely to have at least one relative with kidney disease requiring dialysis or transplantation. Disparities in kidney disease not noted in medical literature until early 1980s When I b...
Source: Harvard Health Blog - February 3, 2021 Category: Consumer Health News Authors: J. Kevin Tucker, MD Tags: Health care disparities Kidney and urinary tract Source Type: blogs