Health Education by Buddhist Monks to Promote Malaria Knowledge and Preventive Practices in Rural Myanmar
Conditions: Buddhist Monks; Health Education; Malaria; Monastery-based; Myanmar; Preventive Practice Interventions: Behavioral: Monastery-based health education by Buddhist monks Sponsors: Myanmar Health Network Organization; College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand.; Department of Public Health, Ministry of Health, Myanmar. Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 26, 2024 Category: Research Source Type: clinical trials

The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy
Conditions: Falciparum; Malaria Interventions: Drug: Artemether-lumefantrine; Drug: Dihydroartemisinin-Piperaquine Sponsors: Infectious Diseases Research Collaboration, Uganda; London School of Hygiene and Tropical Medicine; Radboud University Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 4, 2024 Category: Research Source Type: clinical trials

Seasonal Malaria Chemoprevention Rapid Assessment Study Mozambique
Conditions: Malaria,Falciparum; Chemoprevention Interventions: Drug: Sulfadoxine/pyrimethamine plus amodiaquine Sponsors: Malaria Consortium Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 29, 2024 Category: Research Source Type: clinical trials

A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M ™
Conditions: Malaria,Falciparum Interventions: Biological: R21/Matrix M ™ (Group 1); Biological: R21/Matrix M™ (Group 2); Biological: R21/Matrix M™ (Group 3); Procedure: Fine needle aspiration (FNA) Sponsors: University of Oxford; Bill and Melinda Gates Foundation; University Hospitals Bristol and Weston NHS Foundation Trust Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials

Buikwe Electronic Community Health Information System Impact Study
Conditions: Malaria; Diarrhea; Pneumonia Interventions: Other: eCHIS Sponsors: Malaria Consortium Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials

Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia
Conditions: Plasmodium Falciparum; Malaria; Uncomplicated Malaria Interventions: Drug: Amodiaquine-artesunate (ASAQ); Drug: Artemether+Lumefantrine (AL) Sponsors: Centers for Disease Control and Prevention; Ministry of Health, Liberia Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials

A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)
Conditions: Malaria Interventions: Other: Plasmodium falciparum; Drug: MK-7602; Drug: Artemether/lumefantrine; Drug: Primaquine; Drug: Artesunate; Drug: Atovaquone/proguanil Sponsors: Merck Sharp& Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials

Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge)
Conditions: Malaria,Falciparum Interventions: Biological: CHMI with 3D7 malaria Sponsors: Leiden University Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials

Evaluation of a financial incentive intervention on malaria prevalence among the residents in Lake Victoria basin, Kenya: study protocol for a cluster-randomized controlled trial
This study will aim to develop a demand-side policy tool to encourage local residents ’ active malaria prevention and early treatment-seeking behaviors. We examine the causal impact of a financial incentive intervention complemented with malaria education to residents in malaria-prone areas. A cluster-randomized controlled trial is designed to assess the effect of the financial inc entive intervention on reducing malaria prevalence in residents of Suba South in Homa Bay County, Kenya. The intervention includes two components. The first component is the introduction of a financial incentive scheme tied to negative RDT res...
Source: Trials - March 4, 2024 Category: Research Source Type: clinical trials

A randomised controlled trial to compare the efficacy, safety, and tolerability of low dose, short course primaquine in adults with uncomplicated P. vivax malaria in two hospitals in India
This study will evaluate the efficacy and safety of a 7-day primaquine regimen compared to the standard 14-day regimen in India. Results from this trial are likely to directly inform national treatment guidelines.Trial registrationTrial is registered on CTRI portal, Registration No: CTRI/2022/12/048283. (Source: Trials)
Source: Trials - February 29, 2024 Category: Research Source Type: clinical trials

Efficacy of chlorfenapyr-pyrethroid and piperonyl butoxide-pyrethroid long-lasting insecticidal nets (LLINs) compared to pyrethroid-only LLINs for malaria control in C ôte d’Ivoire: a three group, cluster randomised trial
This study conducted in C ôte d’Ivoire will evaluate the efficacy on epidemiological and entomological outcomes of (1) the control arm: MAGNet® LN, which contains the pyrethroid, alpha-cypermethrin, (2) VEERALIN® LN, a net combining the synergist PBO and alpha-cypermethrin, and (3) Interceptor® G2 LN, which incorporate s chlorfenapyr and alpha-cypermethrin, two adulticides with different mechanisms of action. A total of 33 villages with an average of 200 households per village will be identified, mapped, and randomised in a ratio of 1:1:1. Nets will be distributed at a central point following national guidelines w it...
Source: Trials - February 28, 2024 Category: Research Source Type: clinical trials

Diabetes, Metabolic Syndrome and Risk of Malaria in Cameroon
Conditions: Malaria; Diabetes Mellitus; Metabolic Syndrome; Endemic Sponsors: Karolinska Institutet; University of Dschang; European Foundation for the Study of Diabetes Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Impact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and Antibiotic Use in West Africa
Conditions: Dengue; Chikungunya; Malaria Interventions: Diagnostic Test: VIDAS ® Dengue Antigen NS1, VIDAS® Anti-Dengue IgM, VIDAS® Anti-Dengue IgG, VIDAS® Anti-Chikungunya IgM and VIDAS® Anti-Chikungunya IgG; Other: Standard of care practices Sponsors: BioM érieux Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials

Evaluation of the Protective Efficacy of a Spatial Repellent to Reduce Malaria Prevalence in Uganda
Conditions: Malaria; Mosquito-Borne Disease Interventions: Device: Mossie-Go containing treated transfluthrin disc; Device: Mossie-Go containing untreated blank disc Sponsors: Africa Power Limited; Malaria Consortium; ARCTECH INNOVATION LIMITED Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials

Clinical Validation of Novel Malaria Diagnostic Tools for POC Point-of-Care Testing
Conditions: Malaria; Diagnoses Disease; RDT Sponsors: Foundation for Innovative New Diagnostics, Switzerland; Australian Government Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 26, 2024 Category: Research Source Type: clinical trials