EaveTubes for control of vector-borne diseases in C ôte d’Ivoire: study protocol for a cluster randomized controlled trial
DiscussionFindings will serve as an efficacy trial of ETs and will be submitted to the WHO Vector Control Advisory Group (VCAG) for assessment of public health value. Entomological outcomes will also be measured as proxies of malaria transmission to help develop guidelines for the evaluation of future In2Care ® ETs products.Trial registrationClinicalTrials.gov NCT05736679. Registered on 10 February 2023. (Source: Trials)
Source: Trials - November 2, 2023 Category: Research Source Type: clinical trials

Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawi
Conditions: Malaria,Falciparum; Anemia in Children Interventions: Drug: Dihydroartemisinin-Piperaquine; Drug: Chloroquine; Drug: Sulfadoxine pyrimethamine; Drug: Sulfadoxine-pyrimethamine-amodiaquine Sponsors: Liverpool School of Tropical Medicine; Kamuzu University of Health Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials

Assessment of Safety, Immunogenicity and Efficacy of R21/Matrix-M1 Malaria Vaccine in Healthy WOCBP in Mali
Conditions: Healthy Women of Child Bearing Potential Interventions: Biological: R21/Matrix-M1; Biological: Saline and R21/Matrix-M1; Other: Sterile isotonic (0.9%) normal saline Sponsors: European Vaccine Initiative; University of Oxford; Malaria Research and Training Center, Bamako, Mali Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials

Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo
Conditions: Uncomplicated Plasmodium Falciparum Malaria Interventions: Drug: Artesunate-amodiaquine; Drug: Artemether-lumefantrine Sponsors: Ministry of Public Health, Democratic Republic of the Congo; Centers for Disease Control and Prevention; Global Fund Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 10, 2023 Category: Research Source Type: clinical trials

A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria
Conditions: Malaria Interventions: Biological: BNT165e; Other: Placebo Sponsors: BioNTech SE Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 6, 2023 Category: Research Source Type: clinical trials

Mass Vaccine and Drug Administration, Bangladesh
Conditions: Plasmodium Falciparum Malaria Interventions: Drug: DHA/piperaquine and a SLD-PQ; Biological: Study vaccine R21/Matrix-M ™ Sponsors: University of Oxford Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials

R21/Matrix-M ™ Malaria Vaccine with Novavax’s Adjuvant Technology Receives WHO Recommendation
October 2, 2023 - Today, the World Health Organization (WHO) announced its recommendation of the R21/Matrix-M™ malaria vaccine to prevent malaria in children following advice from its Strategic Advisory Group of Experts (SAGE) and Malaria... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 2, 2023 Category: Pharmaceuticals Source Type: clinical trials

Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax
Conditions:   Efficacy;   Malaria;   Chloroquine;   Vivax Malaria Intervention:   Drug: Chloroquine Plus Primaquine Sponsors:   Dinka Dugassa;   Ethiopian Public Health Institute Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials

Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax
Conditions:   Efficacy;   Malaria;   Chloroquine;   Vivax Malaria Interventions:   Drug: Chloroquine;   Drug: Primaquine Sponsors:   Dinka Dugassa;   Ethiopian Public Health Institute Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials