Effects of Green Light Therapy on Pain-like Behavior and Inflammatory Markers in an Osteoarthritis Model in Rats
Osteoarthritis (OA) is a leading cause of chronic pain, with more women reporting knee OA-related pain and disability than men. Proinflammatory cytokines —namely tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β), and interleukin 6 (IL-6)—are key effectors of knee OA pathogenesis. Standard pain interventions for knee OA remain suboptimal. Green light therapy has recently emerged as a safe and accessible nonpharmacological pain inte rvention, reducing pain in fibromyalgia patients and headache frequency in chronic migraine patients. (Source: The Journal of Pain)
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: Laura Ventura, Renan Santo, Michael Keaser, Youping Zhang, Jin Ro, Joyce Da Silva Source Type: research
An Experimental Phototherapy Device for Studying the Effects of Blue Light on Patients with Raynaud's Phenomenon
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03487-z. Online ahead of print.ABSTRACTRaynaud's phenomenon (RP) is a condition that causes decreased blood flow to areas perfused by small blood vessels (e.g., fingers, toes). In severe cases, ulceration, gangrene, and loss of fingers may occur. Most treatments focus on inducing vasorelaxation in affected areas by the way of pharmaceuticals. Recently, animal studies have shown that vasorelaxation can be induced by non-coherent blue light (wavelength ~ 430-460 nm) through the actions of melanopsin, a photoreceptive opsin protein encoded by the OPN4 gene. To study this ef...
Source: Annals of Biomedical Engineering - March 26, 2024 Category: Biomedical Engineering Authors: Brett Levac James Kerber Emily Wagner Jerry A Molitor Steven S Saliterman Source Type: research
Effectiveness of biomedical interventions on the chronic stage of traumatic brain injury: a systematic review of randomized controlled trials
Traumatic brain injury (TBI), in any form and severity, can pose risks for developing chronic symptoms that can profoundly hinder patients’ work/academic, social, and personal lives. In the past 3 decades, a multitude of pharmacological, stimulation, and exercise-based interventions have been proposed to ameliorate symptoms, memory impairment, mental fatigue, and/or sleep disturbances. However, most research is preliminary, thus limited influence on clinical practice. This review aims to systematically appraise the evidence derived from randomized controlled trials (RCT) regarding the effectiveness of pharmacological, st...
Source: Frontiers in Neurology - March 18, 2024 Category: Neurology Source Type: research
Effects of Combining Music Therapy, Light Therapy, and Chromotherapy in the Treatment of Chronic Pain Patients: A Pilot Study
Discussion. This open pilot study supports the idea that LineQuartz® has a place among complementary therapies dedicated to the treatment of chronic pain. However, these results need to be confirmed by a controlled study.PMID:38482043 | PMC:PMC10937082 | DOI:10.1155/2024/3006352 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - March 14, 2024 Category: Complementary Medicine Authors: Alcira Suarez Yannick Delgado Alain Servais Nicolas Verardi Delphine Durand Severine Litaneur Vincent Wyart Julien Nizard Jean-Paul Nguyen Source Type: research
Bright Light Therapy as Add-On to Inpatient Treatment in Youth With Moderate to Severe Depression
This randomized clinical trial evaluates bright light therapy vs treatment as usual for youth with depression. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - March 13, 2024 Category: Psychiatry Source Type: research
Management of Acne in Pregnancy
AbstractAcne is one of the most common dermatological conditions to affect women of childbearing age, so it is important to consider the safety of long-term acne treatments on women who could become pregnant. In this review article, we clarify what management options are available to treat acne during pregnancy. Topical treatments, typically first-line for acne, such as azelaic acid, clindamycin, erythromycin, metronidazole, benzoyl peroxide, salicylic acid, dapsone, and retinoids, were reviewed. Systemic treatments, such as zinc supplements, cephalexin, cefadroxil, amoxicillin, azithromycin, erythromycin, and corticostero...
Source: American Journal of Clinical Dermatology - March 7, 2024 Category: Dermatology Source Type: research
Light therapy glasses during night shift work: a field study
ConclusionIn the current study, BL glasses were not clearly superior to DRL glasses in ameliorating the negative side effects of night shift work. Despite some limitations, however, this field study showed high ecological validity and demonstrated the convenient use of an intervention that is easy to implement in a realistic workplace setting. (Source: Somnologie - Schlafforschung und Schlafmedizin)
Source: Somnologie - Schlafforschung und Schlafmedizin - March 1, 2024 Category: Sleep Medicine Source Type: research
Non-pharmacological interventions for sleep disruptions and fatigue after traumatic brain injury: a scoping review
CONCLUSION: While this scoping review has utility in describing existing non-pharmacological approaches to manage sleep and fatigue after TBI, the findings suggest that interventions are often developed without considering TBI individuals' source of motivation and the need for support in self-administration. Future studies may achieve greater sustainability by considering the evolving needs of TBI patients and their families and the drivers and barriers that might influence non-pharmacological intervention use at home.PMID:38402580 | DOI:10.1080/02699052.2024.2318599 (Source: Brain Injury)
Source: Brain Injury - February 25, 2024 Category: Neurology Authors: Charles Gervais Danny Hjeij Laura Fern ández-Puerta Caroline Arbour Source Type: research
A study of the biological effects of low-level light
AbstractLow-level light therapy (LLLT), also known as photo biomodulation (PBM), is a type of optical therapy that uses red or near-infrared lasers or light-emitting diodes (LEDs) for medical treatment. The laser wavelengths involved in PBM typically range between 600 –700 nm and 780–1100 nm, with power densities ranging between 5 mW/cm2 and 5 W/cm2. PBM is a series of biochemical cascades exhibited by biological tissues after absorbing a certain amount of energy from light. PBM has been widely used in clinical practice in the past 20 years, and numerous clinical trials have demonstrated its biological efficacy. Ho...
Source: Lasers in Medical Science - February 21, 2024 Category: Laser Surgery Source Type: research
Analysis of factors related to the development of ocular biometric parameters in Chinese children aged 6-10 years: a cross-sectional study
Conclusions
The factors associated with myopia were partly related to ACD and AL, and perinatal factors were associated with myopia and CCT.
Trial registration number
ChiCTR2200065398. (Source: BMJ Open)
Source: BMJ Open - February 6, 2024 Category: General Medicine Authors: Hu, T., Wu, R., Wang, W., Li, H., Peng, X. Tags: Open access, Ophthalmology Source Type: research
Effects of light therapy on sleep and circadian rhythm in older type 2 diabetics living in long-term care facilities: a randomized controlled trial
ConclusionLight therapy had a positive effect on subjective sleep quality and circadian rhythm time type in long-term care residents with type 2 diabetes, and had a possible delayed effect on objective sleep. However, no discernible alterations in blood glucose levels were detected in this study. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - February 5, 2024 Category: Endocrinology Source Type: research
Photobiomodulation CME Part I: Overview and Mechanism of Action
Photobiomodulation (PBM), previously known as low-level laser light therapy, represents a non-invasive form of phototherapy that utilizes wavelengths in the red light (RL, 620-700 nm) portion of the visible light (VL, 400-700 nm) spectrum and the near-infrared (NIR, 700-1440 nm) spectrum. PBM is a promising and increasingly used therapy for the treatment of various dermatologic and non-dermatologic conditions. Photons from RL and NIR are absorbed by endogenous photoreceptors including mitochondrial cytochrome C oxidase (COX). (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - February 1, 2024 Category: Dermatology Authors: Jalal Maghfour, David M. Ozog, Jessica Mineroff, Jared Jagdeo, Indermeet Kohli, Henry W. Lim Tags: Continuing Medical Education Source Type: research
