Photobiomodulation CME Part II: Clinical Applications in Dermatology
Photobiomodulation (PBM) is an emerging treatment modality in dermatology with increasing office and home-based use. PBM is the use of various light sources in the red light (620-700 nm) and near-infrared (700-1440 nm) spectrum as a form of light therapy. PBM is often administered through low-level lasers or light-emitting diodes. Studies show that PBM can be used effectively to treat conditions secondary to cancer therapies, alopecia, ulcers, herpes simplex virus, acne, skin rejuvenation, wounds, and scars. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - January 31, 2024 Category: Dermatology Authors: Jessica Mineroff, Jalal Maghfour, David D. Ozog, Henry W. Lim, Indermeet Kohli, Jared Jagdeo Tags: Continuing Medical Education Source Type: research

Light therapy glasses during night shift work: a  field study
ConclusionIn the current study, BL glasses were not clearly superior to DRL glasses in ameliorating the negative side effects of night shift work. Despite some limitations, however, this field study showed high ecological validity and demonstrated the convenient use of an intervention that is easy to implement in a  realistic workplace setting. (Source: Somnologie - Schlafforschung und Schlafmedizin)
Source: Somnologie - Schlafforschung und Schlafmedizin - January 25, 2024 Category: Sleep Medicine Source Type: research

Open questions regarding the efficacy, mechanisms, and moderators of treatments for circadian sleep-wake disruption in people with dementia
Circadian sleep-wake rhythms are often disrupted in people with dementia (1,2). Since disrupting circadian sleep-wake rhythms experimentally affects mood (3,4), it is plausible that circadian rhythm disruption in people with dementia (PWD) contributes to psychological symptoms. Given that the central circadian system can be entrained or “set” using bright light exposure (5), bright light therapy (BLT) has been considered a potential way to treat circadian rhythm disruption which could reduce related sequalae (e.g., sleep and mood problems) in PWD. (Source: The American Journal of Geriatric Psychiatry)
Source: The American Journal of Geriatric Psychiatry - January 24, 2024 Category: Geriatrics Authors: Dorothy Yam, Stephen F. Smagula Tags: Editorial Source Type: research

Effect of photobiomodulation on postoperative endodontic pain: A systematic review of clinical trials
Conclusion: Although there is some understanding from a cellular viewpoint of the effects ofPMB, there is still some uncertainty about whether these cell ‑level modifications impact reducingthe postendodontic pain.Key Words: Clinical trial, low ‑level light therapy, pain, review, root canal therapy (Source: Dental Research Journal)
Source: Dental Research Journal - January 21, 2024 Category: Dentistry Source Type: research

The Effects of Light Therapy on Sleep, Depression, Neuropsychiatric Behaviors, and Cognition Among People Living With Dementia: A Meta-Analysis of Randomized Controlled Trials
CONCLUSION: Light therapy could be used as a supportive therapy to improve sleep, depression, cognition, and neuropsychiatric behaviors among PLWD.PMID:38216355 | DOI:10.1016/j.jagp.2023.12.010 (Source: Am J Geriatr Psychia...)
Source: Am J Geriatr Psychia... - January 12, 2024 Category: Geriatrics Authors: Nur Aini Ruey Chen Hsin Chu Ching-Yi Chang Hui-Chen Lin Hsiu-Ju Jen Doresses Liu Tso-Ying Lee Kuei-Ru Chou Source Type: research

The Effects of Light Therapy on Sleep, Depression, Neuropsychiatric Behaviors, and Cognition Among People Living With Dementia: A Meta-Analysis of Randomized Controlled Trials
CONCLUSION: Light therapy could be used as a supportive therapy to improve sleep, depression, cognition, and neuropsychiatric behaviors among PLWD.PMID:38216355 | DOI:10.1016/j.jagp.2023.12.010 (Source: The American Journal of Geriatric Psychiatry)
Source: The American Journal of Geriatric Psychiatry - January 12, 2024 Category: Psychiatry Authors: Nur Aini Ruey Chen Hsin Chu Ching-Yi Chang Hui-Chen Lin Hsiu-Ju Jen Doresses Liu Tso-Ying Lee Kuei-Ru Chou Source Type: research

Case report: Diagnosis and intervention of a non-24-h sleep –wake disorder in a sighted child with a psychiatric disorder
Circadian rhythm sleep–wake disorders (CRSWD) are sleep dysfunctions related to circadian functioning. They are characterized by symptoms of insomnia or excessive sleepiness that occur because the intrinsic circadian pacemaker is not entrained to a 24-h light/dark cycle. Affected individuals with a free-running disorder or hypernycthemeral syndrome (N24SWD) have a longer sleep–wake cycle that produces a sleep pattern that typically delays each day. The disorder is seen in 70% of blind people, and among people with healthy vision, it is a rare pathology. Among sighted cases, 80% are young men and 28% have a psychiatric ...
Source: Frontiers in Psychiatry - January 5, 2024 Category: Psychiatry Source Type: research

Chronotherapy for patients with a depressive episode treated in a public outpatient mental healthcare clinic in Norway: protocol for a randomised controlled trial
Introduction Depression is highly prevalent in outpatients receiving treatment for mental disorders. Treatment as usual (TAU) usually consists of either psychotherapy and/or antidepressant medication and often takes several weeks before clinical effect. Chronotherapy, consisting of sleep deprivation, sleep-wake phase advancement and stabilisation, and light therapy, is a possible addition to TAU that may decrease the time to treatment response. This randomised controlled trial will examine the benefits of adding chronotherapy to TAU compared with TAU alone. Methods and analysis The trial will include 76 participants with ...
Source: BMJ Open - January 3, 2024 Category: General Medicine Authors: Ramfjord, L. S., Kahn, N., Langsrud, K., Halvorsen, J. O. O., Morken, G., Saksvik, S., Engvik, L. S. S., Lydersen, S., Kallestad, H. Tags: Open access, Mental health Source Type: research

The Problem With Dry Eye Trials
In this issue of JAMA Ophthalmology, McCann et al are to be commended for undertaking a critical review of the literature on the efficacy and adverse effects of various dry eye therapies. Overall, 71 systematic reviews evaluating interventions for dry eye were included, and of the 26 systemic reviews deemed reliable, no conclusive evidence was identified for the effectiveness of any dry eye intervention. These interventions included environmental modifications, polyunsaturated fatty acid supplementation, artificial tears and lubricants, punctal occlusion, intense pulsed light therapy, vectored thermal pulsation therapy (Li...
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research

The effects of light therapy on sleep, depression, neuropsychiatric behaviors, and cognition among people living with dementia: A meta-analysis of randomized controlled trials
Sleep and circadian rhythm disorders are prevalent among people living with dementia (PLWD),1 due to neurodegeneration of the brain regions and alterations in the suprachiasmatic nucleus (SCN) of the hypothalamus.2 The SCN serves as a pacemaker, controlling circadian rhythms responsible for activity, sleep, and emotional patterns.2, 3 Disruptions in the circadian rhythms coincide with a decline in the quality of nighttime sleep4 impacting on cognitive function.5 Additionally, PLWD experience neuropsychiatric symptoms or behaviors,6 known as behavioral and psychological symptoms of dementia (BPSD),7, 8 that are interrelated...
Source: The American Journal of Geriatric Psychiatry - December 22, 2023 Category: Geriatrics Authors: Nur Aini, Ns.M. Kep, Ruey Chen, Hsin Chu, Ching-Yi Chang, Hui-Chen Lin, Hsiu-Ju Jen, Doresses Liu, Tso-Ying Lee, Kuei-Ru Chou Tags: Regular Research Article Source Type: research

The burning truth about light therapy: a retrospective analysis of the MAUDE database on UV phototherapy and photodynamic therapy complications 2013-2023
DISCUSSION: The COVID-19 pandemic prohibited in-person light treatments, and social distancing requirements may have resulted in increased frequency of home-based light treatments. Hence, while at home treatment may be easier and more accessible, in-office physician supervised UV treatments are associated with less frequent AEs. Moreover, some phototherapy MDRs reported poorly written instructions accompanying the home light box, and some PDT MDRs documented patients receiving inadequate education regarding the procedure. With the rise of at-home treatment options and the ease of obtaining devices on the internet, it is ph...
Source: Pain Physician - December 18, 2023 Category: Anesthesiology Authors: Samantha Jo Albucker Shari R Lipner Source Type: research

Atopic dermatitis (eczema) guidelines: 2023 American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology Joint Task Force on Practice Parameters GRADE- and Institute of Medicine-based recommendations
CONCLUSION: These evidence-based recommendations address optimal use of (1) topical treatments (barrier moisturization devices, corticosteroids, calcineurin inhibitors, PDE4 inhibitors [crisaborole], topical JAK inhibitors, occlusive [wet wrap] therapy, adjunctive antimicrobials, application frequency, maintenance therapy), (2) dilute bleach baths, (3) dietary avoidance/elimination, (4) allergen immunotherapy, and (5) systemic treatments (biologics/monoclonal antibodies, small molecule immunosuppressants [cyclosporine, methotrexate, azathioprine, mycophenolate, JAK inhibitors], and systemic corticosteroids) and UV photothe...
Source: Annals of Allergy, Asthma and Immunology - December 18, 2023 Category: Allergy & Immunology Authors: AAAAI/ACAAI JTF Atopic Dermatitis Guideline Panel Derek K Chu Lynda Schneider Rachel Netahe Asiniwasis Mark Boguniewicz Anna De Benedetto Kathy Ellison Winfred T Frazier Matthew Greenhawt Joey Huynh Elaine Kim Jennifer LeBovidge Mary Laura Lind Peter Lio Source Type: research

The burning truth about light therapy: a retrospective analysis of the MAUDE database on UV phototherapy and photodynamic therapy complications 2013-2023
DISCUSSION: The COVID-19 pandemic prohibited in-person light treatments, and social distancing requirements may have resulted in increased frequency of home-based light treatments. Hence, while at home treatment may be easier and more accessible, in-office physician supervised UV treatments are associated with less frequent AEs. Moreover, some phototherapy MDRs reported poorly written instructions accompanying the home light box, and some PDT MDRs documented patients receiving inadequate education regarding the procedure. With the rise of at-home treatment options and the ease of obtaining devices on the internet, it is ph...
Source: Pain Physician - December 18, 2023 Category: Anesthesiology Authors: Samantha Jo Albucker Shari R Lipner Source Type: research

Atopic dermatitis (eczema) guidelines: 2023 American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology Joint Task Force on Practice Parameters GRADE- and Institute of Medicine-based recommendations
CONCLUSION: These evidence-based recommendations address optimal use of (1) topical treatments (barrier moisturization devices, corticosteroids, calcineurin inhibitors, PDE4 inhibitors [crisaborole], topical JAK inhibitors, occlusive [wet wrap] therapy, adjunctive antimicrobials, application frequency, maintenance therapy), (2) dilute bleach baths, (3) dietary avoidance/elimination, (4) allergen immunotherapy, and (5) systemic treatments (biologics/monoclonal antibodies, small molecule immunosuppressants [cyclosporine, methotrexate, azathioprine, mycophenolate, JAK inhibitors], and systemic corticosteroids) and UV photothe...
Source: Annals of Allergy, Asthma and Immunology - December 18, 2023 Category: Allergy & Immunology Authors: AAAAI/ACAAI JTF Atopic Dermatitis Guideline Panel Derek K Chu Lynda Schneider Rachel Netahe Asiniwasis Mark Boguniewicz Anna De Benedetto Kathy Ellison Winfred T Frazier Matthew Greenhawt Joey Huynh Elaine Kim Jennifer LeBovidge Mary Laura Lind Peter Lio Source Type: research

The burning truth about light therapy: a retrospective analysis of the MAUDE database on UV phototherapy and photodynamic therapy complications 2013 –2023
DiscussionThe COVID-19 pandemic prohibited in-person light treatments, and social distancing requirements may have resulted in increased frequency of home-based light treatments. Hence, while at home treatment may be easier and more accessible, in-office physician supervised UV treatments are associated with less frequent AEs. Moreover, some phototherapy MDRs reported poorly written instructions accompanying the home light box, and some PDT MDRs documented patients receiving inadequate education regarding the procedure. With the rise of at-home treatment options and the ease of obtaining devices on the internet, it is phys...
Source: Archives of Dermatological Research - December 18, 2023 Category: Dermatology Source Type: research