Pregnancy, parturition and postpartum considerations among patients with vulvar lichen sclerosus: A retrospective cross-sectional online survey
CONCLUSION: In this online survey, we found reported symptom severity remained unchanged or decreased during pregnancy, but increased postpartum. Use of topical corticosteroids decreased during pregnancy compared with before and after pregnancy. Half of the respondents reported anxiety regarding VLS and delivery.PMID:37424180 | DOI:10.1111/1471-0528.17601 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - July 10, 2023 Category: OBGYN Authors: Alyssa B Shaffer Sarah T Cigna Rachel Pope Jill M Krapf Source Type: research
Urinary microbiome differences between lichen sclerosus induced and non-lichen sclerosus induced urethral stricture disease
ConclusionsLS USD have significant alterations in diversity and differential abundance of urine microbiota compared to non-LS USD controls. These findings could be used to guide further investigations into the role of the urinary microbiome in LS USD pathogenesis, severity of presentation, and stricture recurrence. (Source: World Journal of Urology)
Source: World Journal of Urology - July 8, 2023 Category: Urology & Nephrology Source Type: research
Unusual acute ulceration of the penile shaft: Lichen sclerosus
Bilgen Erdogan, Elif Nur Özler, Ayşe Şermin Filiz Acıpayam, Zeynep Topkarcı, Damlanur Sakız, Ayşe KavakIndian Journal of Dermatology 2023 68(3):340-342 (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - June 30, 2023 Category: Dermatology Authors: Bilgen Erdogan Elif Nur & #214;zler Ay & #351;e & #350;ermin Filiz Ac & #305;payam Zeynep Topkarc & #305; Damlanur Sak & #305;z Ay & #351;e Kavak Source Type: research
LASER treatment in gynaecology -A randomized controlled trial in women with symptomatic lichen sclerosus
CONCLUSION: Laser treatment with the microablative CO2 laser leads to a significant improvement for symptoms of LS. A higher dosage of laser radiation shows no benefit concerning the symptoms. We have not observed any serious adverse events during this study.PMID:37352640 | DOI:10.1016/j.ejogrb.2023.06.003 (Source: Reproductive Biology)
Source: Reproductive Biology - June 23, 2023 Category: Reproduction Medicine Authors: Elke Krause Stephanie Neumann Marina Maier Sara Imboden Laura Knabben Michael D Mueller Annette Kuhn Source Type: research
LASER treatment in gynaecology -A randomized controlled trial in women with symptomatic lichen sclerosus
CONCLUSION: Laser treatment with the microablative CO2 laser leads to a significant improvement for symptoms of LS. A higher dosage of laser radiation shows no benefit concerning the symptoms. We have not observed any serious adverse events during this study.PMID:37352640 | DOI:10.1016/j.ejogrb.2023.06.003 (Source: Reproductive Biology)
Source: Reproductive Biology - June 23, 2023 Category: Reproduction Medicine Authors: Elke Krause Stephanie Neumann Marina Maier Sara Imboden Laura Knabben Michael D Mueller Annette Kuhn Source Type: research
LASER treatment in gynaecology -A randomized controlled trial in women with symptomatic lichen sclerosus
CONCLUSION: Laser treatment with the microablative CO2 laser leads to a significant improvement for symptoms of LS. A higher dosage of laser radiation shows no benefit concerning the symptoms. We have not observed any serious adverse events during this study.PMID:37352640 | DOI:10.1016/j.ejogrb.2023.06.003 (Source: Reproductive Biology)
Source: Reproductive Biology - June 23, 2023 Category: Reproduction Medicine Authors: Elke Krause Stephanie Neumann Marina Maier Sara Imboden Laura Knabben Michael D Mueller Annette Kuhn Source Type: research
Expression and significance of cyclin D1, cyclin-dependent kinase 4 and cyclin-dependent kinase inhibitor P27 in patients with non-neoplastic epithelial disorders of the vulva
Exp Ther Med. 2023 Jun 2;26(1):356. doi: 10.3892/etm.2023.12055. eCollection 2023 Jul.ABSTRACTNon-neoplastic epithelial disorders of the vulva (NNEDV) are prevalent and refractory gynecological diseases. However, the underlying pathogenesis of these diseases remain unclear. The present study aimed to investigate the expression and significance of cyclin D1, cyclin-dependent kinase 4 (CDK4) and cyclin-dependent kinase inhibitor P27 (P27) in patients with NNEDV and provide a reference for clinical diagnosis and treatment. Normal vulvar skin samples from patients with perineum repair (control group, n=20) and skin samples fro...
Source: Experimental and Therapeutic Medicine - June 16, 2023 Category: General Medicine Authors: Huamei Liu Fan Zhang Zongheng Li Source Type: research
Vulvar Lichen Sclerosus and Vitiligo: Overlap and Clinical Features
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - June 14, 2023 Category: Dermatology Authors: Ilhan Esse, Kathryn Hinchee Rodriquez, Alexa Kassels, Jessica Shiu, Christina Kraus Source Type: research
CO2 LASER versus clobetasol propionate 0,05% on vulvar Lichen Sclerosus treatment for climateric women: pilot-study
Introduction: The vulvar Lichen Sclerosus (LS) is a cutaneous, inflammatory, chronic disease, of probable autoimmune etiology, that affects mainly women on climacteric. The first option of treatment is the high pontent corticosteroid (clobetasol propionate 0,05). However, the CO2 LASER is being considered as a terapeutical option. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Andr éa Cytryn, Yara Lúcia Furtado, Filomena Aste Silveira, João Alfredo Seixas, Amanda Damian, Nereu Gilberto De Moraes Guerra Neto, Gutemberg Leão de Almeida Filho Tags: Abstract ID: 291 Source Type: research
Platelet-rich plasma: a promising therapy for vulvar lichen sclerosus? A systematic review
Purpose: The aim of this systematic review is to evaluate the current evidence regarding the effectiveness of platelet-rich plasma (PRP) for the treatment of vulvar lichen sclerosus (VLS). (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Manuel S ánchez-Prieto, Rafael Sánchez-Borrego, Natanael Antonio Domínguez-Osorio, Otto Eddy Giler-Cantos, Juan José Escribano, Nicolás Mendoza, José Víctor García-Giménez Tags: Abstract ID: 347 Source Type: research
LASER Treatment in Gynaecology –A randomized controlled trial in women with symptomatic Lichen Sclerosus
Objective: Aim of our study was to evaluate the therapeutic effect of laser treatment in vulvar lichen sclerosus, mainly the reduction of existing symptoms as itching, burning and pain. We asked about the different outcome by using different application dosesStudy Design: We conducted a prospective randomized double-blind dose-controlled trial in our dysplasia unit specializing vulvar disorders. 67patients with active LS were included. LS was confirmed by biopsy or by the validated CSS (clinical scoring system of vulvar LS). (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - June 8, 2023 Category: OBGYN Authors: Elke Krause, Stephanie Neumann, Marina Maier, Sara Imboden, Laura Knabben, Michael D. Mueller, Annette Kuhn Tags: Full length article Source Type: research
