A Boy with 46,XX Karyotype (SRY double-positive) having a Leydig Cell Tumor
J Clin Res Pediatr Endocrinol. 2023 Mar 29. doi: 10.4274/jcrpe.galenos.2023.2022-9-14. Online ahead of print.ABSTRACTLeydig cell tumors are the most common type of testicular sex cord stromal tumors. Presence of Y chromosome is associated with tumor risk in sex development disorder (DSD), however tumor development without Y chromosome are extremely rare. A 16-year-old boy diagnosed with Leydig cell tumor due to a mass in the right testis was referred after the right orchiectomy. In physical examination, left testis was 10 ml, and a labium residue in penoscrotal region with bilateral gynecomastia was present. Karyotype was ...
Source: Cell Research - March 29, 2023 Category: Cytology Authors: Merve Gullu Sultan Ayd ın Tarkan Kalkan Tang ül Pınarcı Do ğa Turkkahraman Source Type: research
A Boy with 46,XX Karyotype (SRY double-positive) having a Leydig Cell Tumor
J Clin Res Pediatr Endocrinol. 2023 Mar 29. doi: 10.4274/jcrpe.galenos.2023.2022-9-14. Online ahead of print.ABSTRACTLeydig cell tumors are the most common type of testicular sex cord stromal tumors. Presence of Y chromosome is associated with tumor risk in sex development disorder (DSD), however tumor development without Y chromosome are extremely rare. A 16-year-old boy diagnosed with Leydig cell tumor due to a mass in the right testis was referred after the right orchiectomy. In physical examination, left testis was 10 ml, and a labium residue in penoscrotal region with bilateral gynecomastia was present. Karyotype was ...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - March 29, 2023 Category: Endocrinology Authors: Merve Gullu Sultan Ayd ın Tarkan Kalkan Tang ül Pınarcı Do ğa Turkkahraman Source Type: research
86. Leydig Cell Tumor in an Adolescent
We present a 15-year-old adolescent female with primary amenorrhea and virilization who was found to have a Leydig cell ovarian tumor. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 11, 2023 Category: OBGYN Authors: Lauren Roth, Anne Smith, Natalia Buza, Barbara Coons, David Stitleman, Alla Vash-Margita Source Type: research
Utilization of NKX3.1, P501S, Prostate-Specific Antigen, and Steroidogenic Factor 1 to Distinguish Malignant Leydig Cell Tumor From Metastatic Prostatic Adenocarcinoma to the Testis
CONCLUSIONS.—: The diagnosis of malignant Leydig cell tumor and its distinction from metastatic adenocarcinoma to the testis can be made immunohistochemically on the basis of SF-1 positivity and negativity for NKX3.1.PMID:36881770 | DOI:10.5858/arpa.2022-0424-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - March 7, 2023 Category: Laboratory Medicine Authors: Eric Erak Thomas M Ulbright Jonathan Epstein Source Type: research
Utilization of NKX3.1, P501S, Prostate-Specific Antigen, and Steroidogenic Factor 1 to Distinguish Malignant Leydig Cell Tumor From Metastatic Prostatic Adenocarcinoma to the Testis
CONCLUSIONS.—: The diagnosis of malignant Leydig cell tumor and its distinction from metastatic adenocarcinoma to the testis can be made immunohistochemically on the basis of SF-1 positivity and negativity for NKX3.1.PMID:36881770 | DOI:10.5858/arpa.2022-0424-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - March 7, 2023 Category: Laboratory Medicine Authors: Eric Erak Thomas M Ulbright Jonathan Epstein Source Type: research
