Pediatric primary extra-ovarian Sertoli Leydig cell tumor of the retroperitoneum
We report case of primary retroperitoneal extra-ovarian SLCT in a seven-year girl child without any hormonal manifestation. She presented with complaint of left side abdominal swelling associated with intermittent pain for a duration of six months. CT scan revealed a huge retroperitoneal space-occupying lesion abutting the dorsal vertebrae and present posterior to pancreas, spleen and left kidney. The tumor was diagnosed as extraovarian Sertoli Leydig cell tumor with intermediate differentiation on histopathology and immunohistochemistry.PMID:36656226 | DOI:10.4103/ijpm.ijpm_677_21 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - January 19, 2023 Category: Pathology Authors: Chinmayee Panigrahi Pritinanda Mishra Akash Bihari Pati Kanishka Das Mukund Sable Source Type: research
Pediatric primary extra-ovarian Sertoli Leydig cell tumor of the retroperitoneum
We report case of primary retroperitoneal extra-ovarian SLCT in a seven-year girl child without any hormonal manifestation. She presented with complaint of left side abdominal swelling associated with intermittent pain for a duration of six months. CT scan revealed a huge retroperitoneal space-occupying lesion abutting the dorsal vertebrae and present posterior to pancreas, spleen and left kidney. The tumor was diagnosed as extraovarian Sertoli Leydig cell tumor with intermediate differentiation on histopathology and immunohistochemistry.PMID:36656226 | DOI:10.4103/ijpm.ijpm_677_21 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - January 19, 2023 Category: Pathology Authors: Chinmayee Panigrahi Pritinanda Mishra Akash Bihari Pati Kanishka Das Mukund Sable Source Type: research
Pediatric primary extra-ovarian Sertoli Leydig cell tumor of the retroperitoneum
We report case of primary retroperitoneal extra-ovarian SLCT in a seven-year girl child without any hormonal manifestation. She presented with complaint of left side abdominal swelling associated with intermittent pain for a duration of six months. CT scan revealed a huge retroperitoneal space-occupying lesion abutting the dorsal vertebrae and present posterior to pancreas, spleen and left kidney. The tumor was diagnosed as extraovarian Sertoli Leydig cell tumor with intermediate differentiation on histopathology and immunohistochemistry.PMID:36656226 | DOI:10.4103/ijpm.ijpm_677_21 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - January 19, 2023 Category: Pathology Authors: Chinmayee Panigrahi Pritinanda Mishra Akash Bihari Pati Kanishka Das Mukund Sable Source Type: research
Pediatric primary extra-ovarian Sertoli Leydig cell tumor of the retroperitoneum
We report case of primary retroperitoneal extra-ovarian SLCT in a seven-year girl child without any hormonal manifestation. She presented with complaint of left side abdominal swelling associated with intermittent pain for a duration of six months. CT scan revealed a huge retroperitoneal space-occupying lesion abutting the dorsal vertebrae and present posterior to pancreas, spleen and left kidney. The tumor was diagnosed as extraovarian Sertoli Leydig cell tumor with intermediate differentiation on histopathology and immunohistochemistry.PMID:36656226 | DOI:10.4103/ijpm.ijpm_677_21 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - January 19, 2023 Category: Pathology Authors: Chinmayee Panigrahi Pritinanda Mishra Akash Bihari Pati Kanishka Das Mukund Sable Source Type: research
Pediatric primary extra-ovarian Sertoli Leydig cell tumor of the retroperitoneum
We report case of primary retroperitoneal extra-ovarian SLCT in a seven-year girl child without any hormonal manifestation. She presented with complaint of left side abdominal swelling associated with intermittent pain for a duration of six months. CT scan revealed a huge retroperitoneal space-occupying lesion abutting the dorsal vertebrae and present posterior to pancreas, spleen and left kidney. The tumor was diagnosed as extraovarian Sertoli Leydig cell tumor with intermediate differentiation on histopathology and immunohistochemistry.PMID:36656226 | DOI:10.4103/ijpm.ijpm_677_21 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - January 19, 2023 Category: Pathology Authors: Chinmayee Panigrahi Pritinanda Mishra Akash Bihari Pati Kanishka Das Mukund Sable Source Type: research
Pediatric primary extra-ovarian Sertoli Leydig cell tumor of the retroperitoneum
We report case of primary retroperitoneal extra-ovarian SLCT in a seven-year girl child without any hormonal manifestation. She presented with complaint of left side abdominal swelling associated with intermittent pain for a duration of six months. CT scan revealed a huge retroperitoneal space-occupying lesion abutting the dorsal vertebrae and present posterior to pancreas, spleen and left kidney. The tumor was diagnosed as extraovarian Sertoli Leydig cell tumor with intermediate differentiation on histopathology and immunohistochemistry.PMID:36656226 | DOI:10.4103/ijpm.ijpm_677_21 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - January 19, 2023 Category: Pathology Authors: Chinmayee Panigrahi Pritinanda Mishra Akash Bihari Pati Kanishka Das Mukund Sable Source Type: research
Simultaneous Sertoli Cell-Only Syndrome and Leydig Cell Tumor in a Patient with Azoospermia: A Rare Case Report
This study aims to report a simultaneous Sertoli cell-only syndrome and Leydig cell tumor in the same patient. A 32-year-old man presented with a history of primary infertility for 3 years. Physical exami nation revealed normal secondary sexual characteristics. Two successive seminal fluid analyses revealed azoospermia. A scrotal ultrasound scan showed a 28 × 27 mm hypoechoic and hypervascular right testicular mass. Right radical orchiectomy and simultaneous left testicular biopsy were conducted. Th e histopathological examination revealed Sertoli cell-only syndrome and Leydig cell tumor with focal Leydig cell hyperplasia...
Source: Case Reports in Oncology - December 12, 2022 Category: Cancer & Oncology Source Type: research
Toxoplasma gondii induces MLTC-1 apoptosis via ERS pathway
Exp Parasitol. 2022 Nov 17:108429. doi: 10.1016/j.exppara.2022.108429. Online ahead of print.ABSTRACTToxoplasma gondii (T. gondii) is a serious intracellular parasite and mammalian infection can damage the reproductive system and lead to apoptosis of Murine Leydig tumor cells (MLTC-1); however, the mechanism is unclear. The testis Leydig cell is the main testosterone synthesis cell in male mammals. We studied the mechanism of T. gondii infection on Leydig cell apoptosis in vitro. MLTC-1 were divided into control and experimental groups. Experiment group cells and tachyzoites were co-cultured, in a 1:20 ratio, for 3, 6, 9, ...
Source: Experimental Parasitology - November 20, 2022 Category: Parasitology Authors: Lei Wang Hailun Wang Shihao Wei Xiaoyu Huang Chunchen Yu Qingrui Meng Dengfeng Wang Guangwen Yin Zhijian Huang Source Type: research
Toxoplasma gondii induces MLTC-1 apoptosis via ERS pathway
Exp Parasitol. 2022 Nov 17:108429. doi: 10.1016/j.exppara.2022.108429. Online ahead of print.ABSTRACTToxoplasma gondii (T. gondii) is a serious intracellular parasite and mammalian infection can damage the reproductive system and lead to apoptosis of Murine Leydig tumor cells (MLTC-1); however, the mechanism is unclear. The testis Leydig cell is the main testosterone synthesis cell in male mammals. We studied the mechanism of T. gondii infection on Leydig cell apoptosis in vitro. MLTC-1 were divided into control and experimental groups. Experiment group cells and tachyzoites were co-cultured, in a 1:20 ratio, for 3, 6, 9, ...
Source: Experimental Parasitology - November 20, 2022 Category: Parasitology Authors: Lei Wang Hailun Wang Shihao Wei Xiaoyu Huang Chunchen Yu Qingrui Meng Dengfeng Wang Guangwen Yin Zhijian Huang Source Type: research
Toxoplasma gondii induces MLTC-1 apoptosis via ERS pathway
Exp Parasitol. 2022 Nov 17;244:108429. doi: 10.1016/j.exppara.2022.108429. Online ahead of print.ABSTRACTToxoplasma gondii (T. gondii) is a serious intracellular parasite and mammalian infection can damage the reproductive system and lead to apoptosis of Murine Leydig tumor cells (MLTC-1); however, the mechanism is unclear. The testis Leydig cell is the main testosterone synthesis cell in male mammals. We studied the mechanism of T. gondii infection on Leydig cell apoptosis in vitro. MLTC-1 were divided into control and experimental groups. Experiment group cells and tachyzoites were co-cultured, in a 1:20 ratio, for 3, 6,...
Source: Experimental Parasitology - November 20, 2022 Category: Parasitology Authors: Lei Wang Hailun Wang Shihao Wei Xiaoyu Huang Chunchen Yu Qingrui Meng Dengfeng Wang Guangwen Yin Zhijian Huang Source Type: research
Toxoplasma gondii induces MLTC-1 apoptosis via ERS pathway
Exp Parasitol. 2022 Nov 17;244:108429. doi: 10.1016/j.exppara.2022.108429. Online ahead of print.ABSTRACTToxoplasma gondii (T. gondii) is a serious intracellular parasite and mammalian infection can damage the reproductive system and lead to apoptosis of Murine Leydig tumor cells (MLTC-1); however, the mechanism is unclear. The testis Leydig cell is the main testosterone synthesis cell in male mammals. We studied the mechanism of T. gondii infection on Leydig cell apoptosis in vitro. MLTC-1 were divided into control and experimental groups. Experiment group cells and tachyzoites were co-cultured, in a 1:20 ratio, for 3, 6,...
Source: Experimental Parasitology - November 20, 2022 Category: Parasitology Authors: Lei Wang Hailun Wang Shihao Wei Xiaoyu Huang Chunchen Yu Qingrui Meng Dengfeng Wang Guangwen Yin Zhijian Huang Source Type: research
Toxoplasma gondii induces MLTC-1 apoptosis via ERS pathway
Exp Parasitol. 2022 Nov 17;244:108429. doi: 10.1016/j.exppara.2022.108429. Online ahead of print.ABSTRACTToxoplasma gondii (T. gondii) is a serious intracellular parasite and mammalian infection can damage the reproductive system and lead to apoptosis of Murine Leydig tumor cells (MLTC-1); however, the mechanism is unclear. The testis Leydig cell is the main testosterone synthesis cell in male mammals. We studied the mechanism of T. gondii infection on Leydig cell apoptosis in vitro. MLTC-1 were divided into control and experimental groups. Experiment group cells and tachyzoites were co-cultured, in a 1:20 ratio, for 3, 6,...
Source: Experimental Parasitology - November 20, 2022 Category: Parasitology Authors: Lei Wang Hailun Wang Shihao Wei Xiaoyu Huang Chunchen Yu Qingrui Meng Dengfeng Wang Guangwen Yin Zhijian Huang Source Type: research
DICER1 Mutation in Recurrent Ovarian Sertoli-Leydig Cell Tumor: A Case Report,
DICER1 mutation has been linked to development of Sertoli-Leydig cell tumor and cystic nephroma, among other neoplasms. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - November 15, 2022 Category: OBGYN Authors: Shalon Liu, Alida J. Pokoradi, Donald Soboleski, Timothy Childs, Anita Agrawal Source Type: research
DICER1 mutation in recurrent ovarian Sertoli-Leydig cell tumor: a case report
: DICER1 mutation has been linked to development of Sertoli-Leydig cell tumor and cystic nephroma, among other neoplasms. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - November 15, 2022 Category: OBGYN Authors: Shalon Liu, Alida J. Pokoradi, Donald Soboleski, Timothy Childs, Anita Agrawal Source Type: research
