The relationship between testicular tumour characteristics and azoospermia: a systematic review
Int J Impot Res. 2021 Nov 6. doi: 10.1038/s41443-021-00492-x. Online ahead of print.ABSTRACTSubfertility is a risk factor for testicular cancers (TT), and conversely, TT may induce subfertility due to local and regional toxic effects. We aimed to identify the association between TT characteristics and pre-orchidectomy azoospermia. A systematic review of the literature was performed according to the PRISMA checklist. Overall, eight non-randomised studies involving 469 men with TT (azoospermia, n = 57; no azoospermia n = 412) were included in the qualitative analysis. Bilateral TT (12.3% vs 2.9% in non-azoospermia), non-semi...
Source: Cell Research - November 7, 2021 Category: Cytology Authors: Karl H Pang Nadir I Osman Asif Muneer Hussain M Alnajjar Source Type: research
Characteristics and outcomes analysis of ovarian Sertoli-Leydig cell tumors (SLCTs): analysis of 15 patients
CONCLUSION: The prognosis of SLCTs is good. Our data showed patients with retiform pattern were more likely to exhibit endocrine function. The diameter of tumor was significantly bigger in no endocrine function. Conservative surgery is the preferred option for patients with the desire of fertility at stage Ia. Postoperative chemotherapy is advised to cases with high-risk factors, but the most effective chemotherapy regimen is still uncertain.PMID:34736487 | DOI:10.1186/s13048-021-00909-7 (Source: Cell Research)
Source: Cell Research - November 5, 2021 Category: Cytology Authors: Guangning Wang Ran Zhang Chuan Li Aiping Chen Source Type: research
Krukenberg Tumor of Ovary During Pregnancy: Learning From A Mistake
This report highlights the diagnostic challenges faced by us along with the ways to circumvent them in the future. (Source: International Journal of Gynecological Pathology)
Source: International Journal of Gynecological Pathology - October 10, 2021 Category: Pathology Tags: Pathology of the Upper Tract: Case Report Source Type: research
Immunohistochemical Characterization of 120 Testicular Sex Cord-Stromal Tumors With an Emphasis on the Diagnostic Utility of SOX9, FOXL2, and SF-1
Sex cord-stromal tumors (SCSTs) account for the second most common category of testicular neoplasms and include several entities that may show overlapping morphologies and present diagnostic challenges. We analyzed a cohort of 120 testicular SCSTs and investigated the diagnostic utility of SRY-box transcription factor 9 (SOX9), forkhead box protein L2 (FOXL2), and steroidogenic factor 1 (SF-1) immunohistochemical stains. The results were compared with the more commonly used SCST markers, inhibin α, calretinin, and Wilms’ tumor 1 (WT1). SF-1 was overall the most sensitive stain (91%), followed by inhibin α (70%), calret...
Source: The American Journal of Surgical Pathology - September 19, 2021 Category: Pathology Tags: Original Articles Source Type: research
Contrast-enhanced ultrasound as a valuable imaging modality for characterizing testicular lesions
Asian J Androl. 2021 Sep 14. doi: 10.4103/aja202158. Online ahead of print.ABSTRACTContrast-enhanced ultrasound (CEUS) is a new form of ultrasound (US) that can dynamically display microvessels in a highly sensitive manner. The purpose of this study was to investigate the efficacy of CEUS for characterizing testicular lesions in comparison with conventional US. Forty-seven patients with testicular lesions were enrolled. The histopathology results revealed that 31 cases were neoplastic (11 cases of seminomas, 8 nonseminomatous germ cell tumors, 8 lymphomas, 2 Leydig cell tumors, and 2 nonspecific tumors), and 16 cases were ...
Source: Asian Journal of Andrology - September 16, 2021 Category: Urology & Nephrology Authors: Jie Yu Xin-Hui Jiang Lian-Fang Du Min Bai Zhao-Jun Li Qiu-Sheng Shi Qi Jiang Fan Li Source Type: research
Contrast-enhanced ultrasound as a valuable imaging modality for characterizing testicular lesions
Asian J Androl. 2021 Sep 14. doi: 10.4103/aja202158. Online ahead of print.ABSTRACTContrast-enhanced ultrasound (CEUS) is a new form of ultrasound (US) that can dynamically display microvessels in a highly sensitive manner. The purpose of this study was to investigate the efficacy of CEUS for characterizing testicular lesions in comparison with conventional US. Forty-seven patients with testicular lesions were enrolled. The histopathology results revealed that 31 cases were neoplastic (11 cases of seminomas, 8 nonseminomatous germ cell tumors, 8 lymphomas, 2 Leydig cell tumors, and 2 nonspecific tumors), and 16 cases were ...
Source: Asian Journal of Andrology - September 16, 2021 Category: Urology & Nephrology Authors: Jie Yu Xin-Hui Jiang Lian-Fang Du Min Bai Zhao-Jun Li Qiu-Sheng Shi Qi Jiang Fan Li Source Type: research
Contrast-enhanced ultrasound as a valuable imaging modality for characterizing testicular lesions
Asian J Androl. 2021 Sep 14. doi: 10.4103/aja202158. Online ahead of print.ABSTRACTContrast-enhanced ultrasound (CEUS) is a new form of ultrasound (US) that can dynamically display microvessels in a highly sensitive manner. The purpose of this study was to investigate the efficacy of CEUS for characterizing testicular lesions in comparison with conventional US. Forty-seven patients with testicular lesions were enrolled. The histopathology results revealed that 31 cases were neoplastic (11 cases of seminomas, 8 nonseminomatous germ cell tumors, 8 lymphomas, 2 Leydig cell tumors, and 2 nonspecific tumors), and 16 cases were ...
Source: Asian Journal of Andrology - September 16, 2021 Category: Urology & Nephrology Authors: Jie Yu Xin-Hui Jiang Lian-Fang Du Min Bai Zhao-Jun Li Qiu-Sheng Shi Qi Jiang Fan Li Source Type: research
