Epididymis cell atlas in a patient with a sex development disorder and a novel < em > NR5A1 < /em > gene mutation
This study aims to characterize the cell atlas of the epididymis derived from a 46,XY disorders of sex development (DSD) patient with a novel heterozygous mutation of the nuclear receptor subfamily 5 group A member 1 (NR5A1) gene. Next-generation sequencing found a heterozygous c.124C>G mutation in NR5A1 that resulted in a p.Q42E missense mutation in the conserved DNA-binding domain of NR5A1. The patient demonstrated feminization of external genitalia and Tanner stage 1 breast development. The surgical procedure revealed a morphologically normal epididymis and vas deferens but a dysplastic testis. Microfluidic-based sin...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Jian-Wu Shi Yi-Wen Zhou Yu-Fei Chen Mei Ye Feng Qiao Jia-Wei Tian Meng-Ya Zhang Hao-Cheng Lin Gang-Cai Xie Kin Lam Fok Hui Jiang Yang Liu Hao Chen Source Type: research

A modified fixation technique for the treatment of buried penis in children
This study aimed to explore the clinical effect of a modified fixation technique in treating buried penis in children. Clinical data of 94 patients with buried penis who were treated using the modified penile fixation technique from March 2017 to February 2019 in Fujian Maternity and Child Health Hospital (Fuzhou, China) were retrospectively collected, compared, and analyzed. Clinical data of 107 patients with buried penis who were treated using traditional penile fixation technique from February 2014 to February 2017 were chosen for comparison. The results showed that at 6 months and 12 months after surgery, the penile le...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Xu Cui Bing-Jing Gao Liu Chen Wen-Hua Huang Chao-Ming Zhou Source Type: research

Commentary on "A modified fixation technique for the cure of buried penis in children"
Asian J Androl. 2022 May 10. doi: 10.4103/aja202216. Online ahead of print.NO ABSTRACTPMID:35562125 | DOI:10.4103/aja202216 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Sofia Gereta Adan N Tijerina Safiya-Hana Belbina E Charles Osterberg Source Type: research

Free PSA performs better than total PSA in predicting prostate volume in Chinese men with PSA levels of 2.5-9.9 ng ml < sup > -1 < /sup >
This study investigated whether free prostate-specific antigen (fPSA) performs better than total PSA (tPSA) in predicting prostate volume (PV) in Chinese men with different PSA levels. A total of 5463 men with PSA levels of <10 ng ml-1 and without prostate cancer diagnosis were included in this study. Patients were classified into four groups: PSA <2.5 ng ml-1, 2.5-3.9 ng ml-1, 4.0-9.9 ng ml-1, and 2.5-9.9 ng ml-1. Pearson/Spearman's correlation coefficient (r) and receiver operating characteristic (ROC) curves were used to evaluate the ability of tPSA and fPSA to predict PV. The correlation coefficient between tPSA ...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Ma-Ping Huang Ping Tang Cliff S Klein Xing-Hua Wei Wei Du Jin-Gao Fu Tian-Hai Huang Hui Chen Ke-Ji Xie Source Type: research

Epididymis cell atlas in a patient with a sex development disorder and a novel < em > NR5A1 < /em > gene mutation
This study aims to characterize the cell atlas of the epididymis derived from a 46,XY disorders of sex development (DSD) patient with a novel heterozygous mutation of the nuclear receptor subfamily 5 group A member 1 (NR5A1) gene. Next-generation sequencing found a heterozygous c.124C>G mutation in NR5A1 that resulted in a p.Q42E missense mutation in the conserved DNA-binding domain of NR5A1. The patient demonstrated feminization of external genitalia and Tanner stage 1 breast development. The surgical procedure revealed a morphologically normal epididymis and vas deferens but a dysplastic testis. Microfluidic-based sin...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Jian-Wu Shi Yi-Wen Zhou Yu-Fei Chen Mei Ye Feng Qiao Jia-Wei Tian Meng-Ya Zhang Hao-Cheng Lin Gang-Cai Xie Kin Lam Fok Hui Jiang Yang Liu Hao Chen Source Type: research

A modified fixation technique for the treatment of buried penis in children
This study aimed to explore the clinical effect of a modified fixation technique in treating buried penis in children. Clinical data of 94 patients with buried penis who were treated using the modified penile fixation technique from March 2017 to February 2019 in Fujian Maternity and Child Health Hospital (Fuzhou, China) were retrospectively collected, compared, and analyzed. Clinical data of 107 patients with buried penis who were treated using traditional penile fixation technique from February 2014 to February 2017 were chosen for comparison. The results showed that at 6 months and 12 months after surgery, the penile le...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Xu Cui Bing-Jing Gao Liu Chen Wen-Hua Huang Chao-Ming Zhou Source Type: research

Commentary on "A modified fixation technique for the cure of buried penis in children"
Asian J Androl. 2022 May 10. doi: 10.4103/aja202216. Online ahead of print.NO ABSTRACTPMID:35562125 | DOI:10.4103/aja202216 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Sofia Gereta Adan N Tijerina Safiya-Hana Belbina E Charles Osterberg Source Type: research

Free PSA performs better than total PSA in predicting prostate volume in Chinese men with PSA levels of 2.5-9.9 ng ml < sup > -1 < /sup >
This study investigated whether free prostate-specific antigen (fPSA) performs better than total PSA (tPSA) in predicting prostate volume (PV) in Chinese men with different PSA levels. A total of 5463 men with PSA levels of <10 ng ml-1 and without prostate cancer diagnosis were included in this study. Patients were classified into four groups: PSA <2.5 ng ml-1, 2.5-3.9 ng ml-1, 4.0-9.9 ng ml-1, and 2.5-9.9 ng ml-1. Pearson/Spearman's correlation coefficient (r) and receiver operating characteristic (ROC) curves were used to evaluate the ability of tPSA and fPSA to predict PV. The correlation coefficient between tPSA ...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Ma-Ping Huang Ping Tang Cliff S Klein Xing-Hua Wei Wei Du Jin-Gao Fu Tian-Hai Huang Hui Chen Ke-Ji Xie Source Type: research

Epididymis cell atlas in a patient with a sex development disorder and a novel < em > NR5A1 < /em > gene mutation
This study aims to characterize the cell atlas of the epididymis derived from a 46,XY disorders of sex development (DSD) patient with a novel heterozygous mutation of the nuclear receptor subfamily 5 group A member 1 (NR5A1) gene. Next-generation sequencing found a heterozygous c.124C>G mutation in NR5A1 that resulted in a p.Q42E missense mutation in the conserved DNA-binding domain of NR5A1. The patient demonstrated feminization of external genitalia and Tanner stage 1 breast development. The surgical procedure revealed a morphologically normal epididymis and vas deferens but a dysplastic testis. Microfluidic-based sin...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Jian-Wu Shi Yi-Wen Zhou Yu-Fei Chen Mei Ye Feng Qiao Jia-Wei Tian Meng-Ya Zhang Hao-Cheng Lin Gang-Cai Xie Kin Lam Fok Hui Jiang Yang Liu Hao Chen Source Type: research

A modified fixation technique for the treatment of buried penis in children
This study aimed to explore the clinical effect of a modified fixation technique in treating buried penis in children. Clinical data of 94 patients with buried penis who were treated using the modified penile fixation technique from March 2017 to February 2019 in Fujian Maternity and Child Health Hospital (Fuzhou, China) were retrospectively collected, compared, and analyzed. Clinical data of 107 patients with buried penis who were treated using traditional penile fixation technique from February 2014 to February 2017 were chosen for comparison. The results showed that at 6 months and 12 months after surgery, the penile le...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Xu Cui Bing-Jing Gao Liu Chen Wen-Hua Huang Chao-Ming Zhou Source Type: research

Commentary on "A modified fixation technique for the cure of buried penis in children"
Asian J Androl. 2022 May 10. doi: 10.4103/aja202216. Online ahead of print.NO ABSTRACTPMID:35562125 | DOI:10.4103/aja202216 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Sofia Gereta Adan N Tijerina Safiya-Hana Belbina E Charles Osterberg Source Type: research

Free PSA performs better than total PSA in predicting prostate volume in Chinese men with PSA levels of 2.5-9.9 ng ml < sup > -1 < /sup >
This study investigated whether free prostate-specific antigen (fPSA) performs better than total PSA (tPSA) in predicting prostate volume (PV) in Chinese men with different PSA levels. A total of 5463 men with PSA levels of <10 ng ml-1 and without prostate cancer diagnosis were included in this study. Patients were classified into four groups: PSA <2.5 ng ml-1, 2.5-3.9 ng ml-1, 4.0-9.9 ng ml-1, and 2.5-9.9 ng ml-1. Pearson/Spearman's correlation coefficient (r) and receiver operating characteristic (ROC) curves were used to evaluate the ability of tPSA and fPSA to predict PV. The correlation coefficient between tPSA ...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Ma-Ping Huang Ping Tang Cliff S Klein Xing-Hua Wei Wei Du Jin-Gao Fu Tian-Hai Huang Hui Chen Ke-Ji Xie Source Type: research

Epididymis cell atlas in a patient with a sex development disorder and a novel < em > NR5A1 < /em > gene mutation
This study aims to characterize the cell atlas of the epididymis derived from a 46,XY disorders of sex development (DSD) patient with a novel heterozygous mutation of the nuclear receptor subfamily 5 group A member 1 (NR5A1) gene. Next-generation sequencing found a heterozygous c.124C>G mutation in NR5A1 that resulted in a p.Q42E missense mutation in the conserved DNA-binding domain of NR5A1. The patient demonstrated feminization of external genitalia and Tanner stage 1 breast development. The surgical procedure revealed a morphologically normal epididymis and vas deferens but a dysplastic testis. Microfluidic-based sin...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Jian-Wu Shi Yi-Wen Zhou Yu-Fei Chen Mei Ye Feng Qiao Jia-Wei Tian Meng-Ya Zhang Hao-Cheng Lin Gang-Cai Xie Kin Lam Fok Hui Jiang Yang Liu Hao Chen Source Type: research

A modified fixation technique for the treatment of buried penis in children
This study aimed to explore the clinical effect of a modified fixation technique in treating buried penis in children. Clinical data of 94 patients with buried penis who were treated using the modified penile fixation technique from March 2017 to February 2019 in Fujian Maternity and Child Health Hospital (Fuzhou, China) were retrospectively collected, compared, and analyzed. Clinical data of 107 patients with buried penis who were treated using traditional penile fixation technique from February 2014 to February 2017 were chosen for comparison. The results showed that at 6 months and 12 months after surgery, the penile le...
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Xu Cui Bing-Jing Gao Liu Chen Wen-Hua Huang Chao-Ming Zhou Source Type: research

Commentary on "A modified fixation technique for the cure of buried penis in children"
Asian J Androl. 2022 May 10. doi: 10.4103/aja202216. Online ahead of print.NO ABSTRACTPMID:35562125 | DOI:10.4103/aja202216 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - May 13, 2022 Category: Urology & Nephrology Authors: Sofia Gereta Adan N Tijerina Safiya-Hana Belbina E Charles Osterberg Source Type: research