Effects of anti-inflammatory treatment on efficacy of selective laser trabeculoplasty: A systematic review and meta-analysis
CONCLUSION: Topical anti-inflammatory treatment after SLT for patients with glaucoma neither significantly affected IOP reduction nor remarkably relieved clinical discomfort and anterior chamber inflammation. Hence, regular use of post-SLT anti-inflammatory treatment may be unnecessary.PMID:34524035 | DOI:10.1080/17512433.2021.1981860 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - September 15, 2021 Category: Drugs & Pharmacology Authors: Yu-Sheng Chen Hai-Ting Hung Siao-Pei Guo Hua-Ching Chang Source Type: research

Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma
CONCLUSIONS: The main result of this review was that there was uncertainty as to the difference between fornix- and limbal-based trabeculectomy surgeries due to the small number of events and confidence intervals that cross the null. This also applied to postoperative complications, but without any impact on long-term failure rate between the two surgical techniques.PMID:34437715 | DOI:10.1002/14651858.CD009380.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 26, 2021 Category: General Medicine Authors: Alex B Theventhiran Gene Kim WenJeng Yao Source Type: research

Direct selective laser trabeculoplasty in open angle glaucoma study design: a multicentre, randomised, controlled, investigator-masked trial (GLAUrious)
Br J Ophthalmol. 2021 Aug 25:bjophthalmol-2021-319379. doi: 10.1136/bjophthalmol-2021-319379. Online ahead of print.ABSTRACTINTRODUCTION: Laser trabeculoplasty is an effective and widely used treatment for glaucoma. A new laser technology, the Eagle direct selective laser trabeculoplasty (DSLT) device, may provide automated, fast, simple, safe and effective laser treatment for glaucoma in a broader range of clinical settings. This trial aims to test the hypothesis that translimbal DSLT is effective and not inferior to selective laser trabeculoplasty (SLT) in reducing intraocular pressure (IOP) in open angle glaucoma (OAG)....
Source: The British Journal of Ophthalmology - August 26, 2021 Category: Opthalmology Authors: Nathan Congdon Augusto Azuara-Blanco Yoram Solberg Carlo E Traverso Michele Lester Carlo Alberto Cutolo Alessandro Bagnis Tin Aung Scott J Fudemberg Richard Lindstrom Thomas Samuelson Kuldev Singh Eytan Z Blumenthal Gus Gazzard GLAUrious study group Source Type: research

Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma
CONCLUSIONS: The main result of this review was that there was uncertainty as to the difference between fornix- and limbal-based trabeculectomy surgeries due to the small number of events and confidence intervals that cross the null. This also applied to postoperative complications, but without any impact on long-term failure rate between the two surgical techniques.PMID:34437715 | DOI:10.1002/14651858.CD009380.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 26, 2021 Category: General Medicine Authors: Alex B Theventhiran Gene Kim WenJeng Yao Source Type: research

Direct selective laser trabeculoplasty in open angle glaucoma study design: a multicentre, randomised, controlled, investigator-masked trial (GLAUrious)
Br J Ophthalmol. 2021 Aug 25:bjophthalmol-2021-319379. doi: 10.1136/bjophthalmol-2021-319379. Online ahead of print.ABSTRACTINTRODUCTION: Laser trabeculoplasty is an effective and widely used treatment for glaucoma. A new laser technology, the Eagle direct selective laser trabeculoplasty (DSLT) device, may provide automated, fast, simple, safe and effective laser treatment for glaucoma in a broader range of clinical settings. This trial aims to test the hypothesis that translimbal DSLT is effective and not inferior to selective laser trabeculoplasty (SLT) in reducing intraocular pressure (IOP) in open angle glaucoma (OAG)....
Source: The British Journal of Ophthalmology - August 26, 2021 Category: Opthalmology Authors: Nathan Congdon Augusto Azuara-Blanco Yoram Solberg Carlo E Traverso Michele Lester Carlo Alberto Cutolo Alessandro Bagnis Tin Aung Scott J Fudemberg Richard Lindstrom Thomas Samuelson Kuldev Singh Eytan Z Blumenthal Gus Gazzard GLAUrious study group Source Type: research

Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma
CONCLUSIONS: The main result of this review was that there was uncertainty as to the difference between fornix- and limbal-based trabeculectomy surgeries due to the small number of events and confidence intervals that cross the null. This also applied to postoperative complications, but without any impact on long-term failure rate between the two surgical techniques.PMID:34437715 | DOI:10.1002/14651858.CD009380.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 26, 2021 Category: General Medicine Authors: Alex B Theventhiran Gene Kim WenJeng Yao Source Type: research

Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma
CONCLUSIONS: The main result of this review was that there was uncertainty as to the difference between fornix- and limbal-based trabeculectomy surgeries due to the small number of events and confidence intervals that cross the null. This also applied to postoperative complications, but without any impact on long-term failure rate between the two surgical techniques.PMID:34437715 | PMC:PMC8407098 | DOI:10.1002/14651858.CD009380.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 26, 2021 Category: General Medicine Authors: Alex B Theventhiran Gene Kim WenJeng Yao Source Type: research

Selective laser trabeculoplasty (SLT) performed by optometrists—enablers and barriers to a shift in service delivery
Eye, Published online: 13 August 2021; doi:10.1038/s41433-021-01746-0Selective laser trabeculoplasty (SLT) performed by optometrists—enablers and barriers to a shift in service delivery (Source: Eye)
Source: Eye - August 13, 2021 Category: Opthalmology Authors: Evgenia Konstantakopoulou Lee Jones Neil Nathwani Gus Gazzard Source Type: research

Selective laser trabeculoplasty lowered the untreated fellow eye long-term intraocular pressure: a 3-year observational study
AbstractTo explore the long-term intraocular pressure (IOP)-lowering effect of monocular selective laser trabeculoplasty (SLT) in the untreated fellow eyes of open-angle glaucoma (OAG) patients. This was a retrospective observational study. Consecutive Chinese OAG patients who received monocular SLT treatment were included in this study. One hundred and eighty degree SLT was conducted as adjunctive treatment when anti-glaucoma medication was not sufficiently effective after clinical evaluation. Treatment success was defined as more than 20% IOP reduction of the baseline IOP levels. IOP-decreasing amplitude and SLT success ...
Source: Lasers in Medical Science - August 5, 2021 Category: Laser Surgery Source Type: research

In vivo imaging of the Schlemm's Canal and the response to Selective laser trabeculoplasty
: To evaluate the presence of angle dysgenesis on ASOCT (ADoA) as a predictive factor in determining outcomes of selective laser trabeculoplasty (SLT). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 18, 2021 Category: Opthalmology Authors: Toshit Varshney, Kishan Azmira, Shikha Gupta, Karthikeyan Mahalingam, Abhishek Singh, Dewang Angmo, Viney Gupta Source Type: research

Low-energy Selective Laser Trabeculoplasty Repeated Annually: Rationale for the COAST Trial
The recent Laser in Glaucoma and Ocular Hypertension Trial provided the evidentiary basis for a paradigm shift away from the historical medication-first approach to glaucoma--which has numerous limitations, the most important of which is poor adherence to therapy --and toward a laser-first approach. Now 20 years after its commercialization, selective laser trabeculoplasty (SLT) is routinely performed consistently with its initial description, with energy titrated to the appearance of fine, champagne-like cavitation bubbles. A recent data set suggested that lower energy SLT, applied as primary therapy and repeated annually ...
Source: Journal of Glaucoma - July 1, 2021 Category: Opthalmology Tags: Advances in Glaucoma Surgery: Perspective Source Type: research

Long-Term Outcomes of Selective Laser Trabeculoplasty for Open-Angle Glaucoma in the Caribbean
To characterize long-term clinical outcomes of monotherapy selective laser trabeculoplasty (SLT) in Afro-Caribbean patients with open-angle glaucoma (OAG). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - June 18, 2021 Category: Opthalmology Authors: Tony Realini, Hazel Shillingford-Ricketts, Darra Burt, Goundappa K. Balasubramani Tags: Original Articles Source Type: research

Selective laser trabeculoplasty in steroid-induced and uveitic glaucoma
CONCLUSIONS: SLT is an effective treatment for steroid-induced glaucoma, with greater response and a lower failure rate than in PEX and primary POAG, although high baseline intraocular pressure may be a confounder. Judicious use of SLT can be considered in uveitic glaucoma.PMID:34119463 | DOI:10.1016/j.jcjo.2021.05.006 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - June 13, 2021 Category: Opthalmology Authors: Yujia Zhou Christopher M Pruet Chengbo Fang Cheryl L Khanna Source Type: research

Outcomes of selective laser trabeculoplasty in corticosteroid-induced ocular hypertension and glaucoma
CONCLUSION: SLT is a safe and effective procedure that can result in well-controlled IOP in patients with steroid-induced ocular hypertension and glaucoma.PMID:34096363 | DOI:10.1177/11206721211023310 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - June 7, 2021 Category: Opthalmology Authors: Ibrahim AlObaida Adi Mohammed Al Owaifeer Hajar Alotaibi Aisha Alsafi Leyla Ali Aljasim Source Type: research

Outcomes of selective laser trabeculoplasty in corticosteroid-induced ocular hypertension and glaucoma
CONCLUSION: SLT is a safe and effective procedure that can result in well-controlled IOP in patients with steroid-induced ocular hypertension and glaucoma.PMID:34096363 | DOI:10.1177/11206721211023310 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - June 7, 2021 Category: Opthalmology Authors: Ibrahim AlObaida Adi Mohammed Al Owaifeer Hajar Alotaibi Aisha Alsafi Leyla Ali Aljasim Source Type: research