Clinical outcomes following selective laser trabeculoplasty in Afro-Caribbean patients with glaucoma at high risk for progression
Conclusions Afro-Caribbean patients with OAG at risk for progression can achieve clinically and statistically significant reductions in IOP or medications through up to 24 months following a single 360° SLT treatment. Trial registration number NCT02375009. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - August 19, 2022 Category: Opthalmology Authors: Realini, T., Shillingford-Ricketts, H., Burt, D., Balasubramani, G. K. Tags: Original articles - Clinical science Source Type: research

Is selective laser trabeculoplasty shifting the glaucoma treatment paradigm in developing countries?
In 2019, the Laser in Glaucoma and Ocular Hypertension (LiGHT) randomised controlled trial reported that initial treatment with selective laser trabeculoplasty (SLT) is more cost effective than initial treatment with pressure-lowering eye drops, leading to a reduced number of glaucoma surgeries and very low rates of adverse events while providing drop-free intraocular pressure (IOP) control to 78% of treated eyes after 3 years.1 2 As a result, the European Glaucoma Society,3 the American Academy of Ophthalmology4 and the UK National Institute for Health and Care Excellence5 now recommend the use of SLT as initial treatment...
Source: British Journal of Ophthalmology - August 19, 2022 Category: Opthalmology Authors: Konstantakopoulou, E., Gazzard, G. Tags: Open access Editorials Source Type: research

Selective laser trabeculoplasty is safe and effective in patients previously treated with prostaglandin analogs: An evidence-based review
ConclusionsCost-effectiveness, patient compliance, and antiglaucoma drugs ā€™ side effects, including higher surgical failure, favor consideration of SLT as first-line therapy for OAG and OHT. Furthermore, SLT efficacy does not seem to be affected by prior PGA administration; however, larger cohort, comparative, multicenter RCTs are necessary to answer this question. (Source: International Ophthalmology)
Source: International Ophthalmology - August 13, 2022 Category: Opthalmology Source Type: research

Laser trabeculoplasty for open-angle glaucoma and ocular hypertension
CONCLUSIONS: Laser trabeculoplasty may work better than topical medication in slowing down the progression of open-angle glaucoma (rate of visual field loss) and may be similar to modern eye drops in controlling eye pressure at a lower cost. It is not associated with serious unwanted effects, particularly for the newer types of trabeculoplasty, such as selective laser trabeculoplasty.PMID:35943114 | DOI:10.1002/14651858.CD003919.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 9, 2022 Category: General Medicine Authors: Christiane R Rolim-de-Moura Augusto Paranhos Mohamed Loutfi David Burton Richard Wormald Jennifer R Evans Source Type: research

Laser trabeculoplasty for open-angle glaucoma and ocular hypertension
CONCLUSIONS: Laser trabeculoplasty may work better than topical medication in slowing down the progression of open-angle glaucoma (rate of visual field loss) and may be similar to modern eye drops in controlling eye pressure at a lower cost. It is not associated with serious unwanted effects, particularly for the newer types of trabeculoplasty, such as selective laser trabeculoplasty.PMID:35943114 | PMC:PMC9361429 | DOI:10.1002/14651858.CD003919.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 9, 2022 Category: General Medicine Authors: Christiane R Rolim-de-Moura Augusto Paranhos Mohamed Loutfi David Burton Richard Wormald Jennifer R Evans Source Type: research

Energy Dose-Response in Selective Laser Trabeculoplasty: A Review
Conclusions: The optimal energy level of SLT needed for IOP reduction has not yet been definitively established, with all reported pulse energies resulting in similar IOP reduction. Furthermore, similar lack of conclusive findings exists regarding optimal SLT energy dosage for use in different races and degrees of trabecular meshwork pigmentation. This parameter and each of the abovementioned factors requires further research. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - August 1, 2022 Category: Opthalmology Tags: Celebrating 30 Years of the Journal of Glaucoma: Review Article Source Type: research

Laser Induced Damage to Disposable Gonioscopy Lenses During Selective Laser Trabeculoplasty
The substitution of reusable gonioscopy lenses for disposable gonioscopy lenses during selective laser trabeculoplasty (SLT) has occurred over the last few years to mitigate infection risk. However, concerns have been raised regarding the potential of laser damage to the lens itself during SLT, which can lead to laser scattering, increasing the possibility of unintended adverse effects. We have noticed that over 90% of the disposable lenses used for SLT sustained some sort of laser-induced damage with routine laser energies (0.4ā€“1.0ā€‰mJ). Comparisons of clinical efficacy of SLT, measured by reductions in intraocular pre...
Source: Journal of Glaucoma - June 29, 2022 Category: Opthalmology Tags: New Glaucoma Insights: Brief Reports Source Type: research

Glaucoma Treatment Outcomes in Open Angle Glaucoma Patients of African Descent
Open angle glaucoma (OAG), characterized by structural changes to the optic nerve head and retinal nerve fiber layer, is a progressive multifactorial optic neuropathy and a leading cause of irreversible blindness globally. Currently, intraocular pressure is the only modifiable risk factor; however, others have been identified, including genetics and race. Importantly, OAG is much more prevalent in persons of African descent (AD) compared with those of European descent (ED). OAG patients of AD are also known to have a more severe course of the disease, a finding potentially explained by structural and/or vascular difference...
Source: Journal of Glaucoma - June 29, 2022 Category: Opthalmology Tags: New Glaucoma Insights: Review Article Source Type: research

Selective laser trabeculoplasty for steroid-induced ocular hypertension following endothelial keratoplasty
Conclusions: SLT may be a safe and effective treatment option that reduces topical antihypertensive burden while allowing continuance of corticosteroids in steroid-responsive eyes at high risk of rejection following endothelial keratoplasty. Larger randomized studies are needed to compare SLT efficacy with topical medication in this patient group and to review any impact on graft survival and glaucoma progression.PMID:35686724 | DOI:10.1080/02713683.2022.2088800 (Source: Current Eye Research)
Source: Current Eye Research - June 10, 2022 Category: Opthalmology Authors: Max Davidson Eran Berkowitz Harry Roberts Ahmed Wanas James Myerscough Source Type: research

Selective laser trabeculoplasty for steroid-induced ocular hypertension following endothelial keratoplasty
Conclusions: SLT may be a safe and effective treatment option that reduces topical antihypertensive burden while allowing continuance of corticosteroids in steroid-responsive eyes at high risk of rejection following endothelial keratoplasty. Larger randomized studies are needed to compare SLT efficacy with topical medication in this patient group and to review any impact on graft survival and glaucoma progression.PMID:35686724 | DOI:10.1080/02713683.2022.2088800 (Source: Current Eye Research)
Source: Current Eye Research - June 10, 2022 Category: Opthalmology Authors: Max Davidson Eran Berkowitz Harry Roberts Ahmed Wanas James Myerscough Source Type: research

Selective laser trabeculoplasty for steroid-induced ocular hypertension following endothelial keratoplasty
Conclusions: SLT may be a safe and effective treatment option that reduces topical antihypertensive burden while allowing continuance of corticosteroids in steroid-responsive eyes at high risk of rejection following endothelial keratoplasty. Larger randomized studies are needed to compare SLT efficacy with topical medication in this patient group and to review any impact on graft survival and glaucoma progression.PMID:35686724 | DOI:10.1080/02713683.2022.2088800 (Source: Current Eye Research)
Source: Current Eye Research - June 10, 2022 Category: Opthalmology Authors: Max Davidson Eran Berkowitz Harry Roberts Ahmed Wanas James Myerscough Source Type: research

Selective laser trabeculoplasty for steroid-induced ocular hypertension following endothelial keratoplasty
Conclusions: SLT may be a safe and effective treatment option that reduces topical antihypertensive burden while allowing continuance of corticosteroids in steroid-responsive eyes at high risk of rejection following endothelial keratoplasty. Larger randomized studies are needed to compare SLT efficacy with topical medication in this patient group and to review any impact on graft survival and glaucoma progression.PMID:35686724 | DOI:10.1080/02713683.2022.2088800 (Source: Current Eye Research)
Source: Current Eye Research - June 10, 2022 Category: Opthalmology Authors: Max Davidson Eran Berkowitz Harry Roberts Ahmed Wanas James Myerscough Source Type: research

Selective laser trabeculoplasty for steroid-induced ocular hypertension following endothelial keratoplasty
Conclusions: SLT may be a safe and effective treatment option that reduces topical antihypertensive burden while allowing continuance of corticosteroids in steroid-responsive eyes at high risk of rejection following endothelial keratoplasty. Larger randomized studies are needed to compare SLT efficacy with topical medication in this patient group and to review any impact on graft survival and glaucoma progression.PMID:35686724 | DOI:10.1080/02713683.2022.2088800 (Source: Current Eye Research)
Source: Current Eye Research - June 10, 2022 Category: Opthalmology Authors: Max Davidson Eran Berkowitz Harry Roberts Ahmed Wanas James Myerscough Source Type: research

Selective laser trabeculoplasty for steroid-induced ocular hypertension following endothelial keratoplasty
Conclusions: SLT may be a safe and effective treatment option that reduces topical antihypertensive burden while allowing continuance of corticosteroids in steroid-responsive eyes at high risk of rejection following endothelial keratoplasty. Larger randomized studies are needed to compare SLT efficacy with topical medication in this patient group and to review any impact on graft survival and glaucoma progression.PMID:35686724 | DOI:10.1080/02713683.2022.2088800 (Source: Current Eye Research)
Source: Current Eye Research - June 10, 2022 Category: Opthalmology Authors: Max Davidson Eran Berkowitz Harry Roberts Ahmed Wanas James Myerscough Source Type: research

Micropulse laser trabeculoplasty on Chinese patients with glaucoma or ocular hypertension: average 35 months follow-up results
Glaucoma is a group of eye diseases that can damage the optic nerve and cause vision loss. A novel technology micropulse laser trabeculoplasty (MLT) can use duty-circle subvisible laser pulses to treat glaucom... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - June 4, 2022 Category: Opthalmology Authors: Yuting Yang, Xinting Huang, Sheng Liao, Feng Zhang, Jingming Shi, Xuanchu Duan and Ke Liu Tags: Research Source Type: research