A comparative study of intravenous labetalol VS intravenous Nitroglycerin in the treatment of hypertensive crises
Indian Heart J. 2022 Jun 3:S0019-4832(22)00097-9. doi: 10.1016/j.ihj.2022.06.001. Online ahead of print.ABSTRACTHypertensive crises is still a major public health problem, causing end organ damage like myocardial infarction, stroke, and renal failure. Labetalol and nitroglycerine are among the two most commonly used medicine to control the blood pressure, but there is no head to head comparison between these two medicines. This was a prospective randomized non-blinded study which included 50 patients of hypertensive crises, out which 25 patients received intravenous labetalol and 25 patients received intravenous nitroglyce...
Source: Indian Heart J - June 6, 2022 Category: Cardiology Authors: M O H A M M A D A Z H A R U D D I N Malik R E H A N Ahmad M U J A H I D Beg R I Z W A N Ahmad Source Type: research
A comparative study of intravenous labetalol VS intravenous Nitroglycerin in the treatment of hypertensive crises
Indian Heart J. 2022 Jun 3:S0019-4832(22)00097-9. doi: 10.1016/j.ihj.2022.06.001. Online ahead of print.ABSTRACTHypertensive crises is still a major public health problem, causing end organ damage like myocardial infarction, stroke, and renal failure. Labetalol and nitroglycerine are among the two most commonly used medicine to control the blood pressure, but there is no head to head comparison between these two medicines. This was a prospective randomized non-blinded study which included 50 patients of hypertensive crises, out which 25 patients received intravenous labetalol and 25 patients received intravenous nitroglyce...
Source: Indian Heart J - June 6, 2022 Category: Cardiology Authors: M O H A M M A D A Z H A R U D D I N Malik R E H A N Ahmad M U J A H I D Beg R I Z W A N Ahmad Source Type: research
Interpretation of the Urine Drug Screen
Dr. Cunningham
Case A 40-year-old male with depression, post-traumatic stress disorder, and chronic pain presents with somnolence and a respiratory rate of 10 breaths per minute that responded to naloxone in the field. The patient’s outpatient prescriptions include sertraline, prazosin, and as-needed hydrocodone. The urine drug screen (UDS) is positive for opiates and benzodiazepines.
Dr. Gillespie
Brief overview Although UDS is commonly ordered and easy to perform, interpretation isn’t straightforward and misinterpretation is common.1 Toxicology literature cites significant limitations to the UDS, both diagnostic...
Source: The Hospitalist - May 2, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Addiction Medicine Diagnostic Interpreting Diagnostic Tests Source Type: research
Case Report: Giant Paraganglioma of the Skull Base With Two Somatic Mutations in SDHB and PTEN Genes
We report a case of a giant paraganglioma of the skull base with an unusually severe presentation secondary to excessive release of norepinephrine, with a good outcome considering the severity of disease. A 39-year-old Caucasian woman with no prior medical history was found unconscious and emaciated in her home. In the intensive care unit (ICU) the patient was treated for multi-organ failure with multiple complications and difficulties in stabilizing her blood pressure with values up to 246/146 mmHg. She was hospitalized in the ICU for 72 days and on the 31st day clinical assessment revealed jugular foramen syndrome and pa...
Source: Frontiers in Endocrinology - April 13, 2022 Category: Endocrinology Source Type: research
Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials
CONCLUSION: These findings demonstrated the superiority of oral nifedipine 50,60,90 mg, especially oral nifedipine 50 mg tablets, in the treatment of severe hypertension during pregnancy than IV labetalol 300 mg, while oral nifedipine 60,90 mg also showed superiority in the successful treatment rate of severe hypertension during pregnancy than IV hydralazine 15,25 mg. However, the limitations of the underlying data indicate that future large-scale and rigorous RCTs are needed to confirm such findings.PMID:35361052 | DOI:10.1080/10641955.2022.2056196 (Source: Hypertension in Pregnancy)
Source: Hypertension in Pregnancy - April 1, 2022 Category: OBGYN Authors: Hui-Zhen Wu Yuan Cheng Ding Yu Ji-Bin Li Yun-Fa Jiang Zhong-Ning Zhu Source Type: research
Hypertensive Disorders of Pregnancy: Common Clinical Conundrums
Conclusion and Relevance
Despite the frequency with which hypertensive disorders of pregnancy are encountered clinically, situations arise frequently with limited evidence to guide providers in their management. An urgent need exists to better understand this disease to optimize outcomes for impacted patients.
Target Audience
Obstetricians and gynecologists, family physicians
Learning Objectives
After completing this activity, the learner should be better able to describe the diagnosis and delineation between various preeclampsia spectrum disorders; distinguish imitators of preeclampsia from preeclampsia;...
Source: Obstetrical and Gynecological Survey - April 1, 2022 Category: OBGYN Tags: CME ARTICLES Source Type: research
Antihypertensive Drugs and Perinatal Outcomes in Hypertensive Women Attending a Specialized Tertiary Hospital
CONCLUSIONS: Labetalol was the most commonly prescribed antihypertensive drug in this cohort, and women on combined antihypertensive medications had significantly higher maternal and fetal complications. A larger prospective study including hypertensive women with or without antihypertensive medications in more than one center is needed to evaluate the effect of these drugs on perinatal outcomes.PMID:35356366 | PMC:PMC8961539 | DOI:10.5001/omj.2022.43 (Source: Oman Medical Journal)
Source: Oman Medical Journal - March 31, 2022 Category: Middle East Health Authors: Al-Khatab Al Ismaili Tamima Al-Duqhaishi Hajar Al Rajaibi Khalid Al Waili Khalid Al Rasadi Sunail K Nadar Khamis Al Hashmi Source Type: research
