IJERPH, Vol. 20, Pages 6153: Prevalence of Hypertensive Disorders, Antihypertensive Therapy and Pregnancy Outcomes among Pregnant Women: A Retrospective Review of Cases at Tamale Teaching Hospital, Ghana
lu Nlooto
Hypertensive disorders associated with pregnancy are a major health concern and a leading cause of maternal indisposition and transience. The main objective of this study was to assess the prevalence of hypertension in pregnancy as well as antihypertensive therapy and pregnancy outcomes among pregnant women at Tamale Teaching Hospital (TTH) in Ghana. This was a retrospective study conducted using data from the folders of pregnant hypertensive patients. The study was conducted at the maternity ward of TTH from 1 June 2018 to 31 May 2019. Participants were all pregnant women with a diagnosis of hypertensive dis...
Source: International Journal of Environmental Research and Public Health - June 16, 2023 Category: Environmental Health Authors: Amos Adapalala Bugri Solomon Kwabena Gumanga Peter Yamoah Ebenezer Kwabena Frimpong Manimbulu Nlooto Tags: Article Source Type: research
Hypoxia associated with dihydropyridine calcium channel inhibitors: a pharmacovigilance study in VigiBase ®
Clin Pharmacol Ther. 2023 Jun 13. doi: 10.1002/cpt.2970. Online ahead of print.ABSTRACTDue to their negative effects on hypoxic pulmonary vasoconstriction (HPV), dihydropyridine calcium channel inhibitors (DCCIs) can lead to hypoxia in patients with a pulmonary shunt. To date, only preclinical studies and case reports have focused on this potential adverse drug reaction. We aimed to assess the reporting association between DCCIs and hypoxia using the World Health Organization pharmacovigilance database (VigiBase®). We performed a disproportionality analysis to evaluate the strength of the reporting association between int...
Source: Clinical Pharmacology and Therapeutics - June 13, 2023 Category: Drugs & Pharmacology Authors: Basile Chr étien Jean Baptiste Decros Florimond Suard Charles Dolladille Marc-Olivier Fischer Joachim Alexandre Richard Descamps Source Type: research
Hypoxia associated with dihydropyridine calcium channel inhibitors: a pharmacovigilance study in VigiBase ®
Clin Pharmacol Ther. 2023 Jun 13. doi: 10.1002/cpt.2970. Online ahead of print.ABSTRACTDue to their negative effects on hypoxic pulmonary vasoconstriction (HPV), dihydropyridine calcium channel inhibitors (DCCIs) can lead to hypoxia in patients with a pulmonary shunt. To date, only preclinical studies and case reports have focused on this potential adverse drug reaction. We aimed to assess the reporting association between DCCIs and hypoxia using the World Health Organization pharmacovigilance database (VigiBase®). We performed a disproportionality analysis to evaluate the strength of the reporting association between int...
Source: Clinical Pharmacology and Therapeutics - June 13, 2023 Category: Drugs & Pharmacology Authors: Basile Chr étien Jean Baptiste Decros Florimond Suard Charles Dolladille Marc-Olivier Fischer Joachim Alexandre Richard Descamps Source Type: research
Hypertension in Pregnancy: A Diagnostic and Therapeutic Overview
AbstractHypertensive disorders in pregnancy are associated with increased risk of maternal, fetal, and neonatal morbidity and mortality. It is important to distinguish between pre-existing (chronic) hypertension and gestational hypertension, developing after 20 weeks of gestation and usually resolving within 6 weeks postpartum. There is a consensus that systolic blood pressure ≥ 170 or diastolic blood pressure ≥ 110 mmHg is an emergency and hospitalization is indicated. The selection of the antihypertensive drug and its route of administration depend on the expected time of delivery. The current European guidelines r...
Source: High Blood Pressure and Cardiovascular Prevention - June 13, 2023 Category: Cardiology Source Type: research
Comparing the efficacy of oral labetalol with oral amlodipine in achieving blood pressure control in women with postpartum hypertension: randomized controlled trial (HIPPO study—Hypertension In Pregnancy & Postpartum Oral-antihypertensive therapy)
Journal of Human Hypertension, Published online: 25 May 2023; doi:10.1038/s41371-023-00841-xComparing the efficacy of oral labetalol with oral amlodipine in achieving blood pressure control in women with postpartum hypertension: randomized controlled trial (HIPPO study—Hypertension In Pregnancy & Postpartum Oral-antihypertensive therapy) (Source: Journal of Human Hypertension)
Source: Journal of Human Hypertension - May 25, 2023 Category: Cardiology Authors: Avantika Gupta Deepthi Nayak Jyotsna Sharma Anish Keepanasseril Source Type: research
Psychiatric and non-psychiatric drugs causing false positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS
Expert Rev Clin Pharmacol. 2023 May 5. doi: 10.1080/17512433.2023.2211261. Online ahead of print.ABSTRACTINTRODUCTION: Immunoassay urine drug screen (UDS) is frequently used in clinical practice for initial screening process, being generally available, fast, and inexpensive. Exposure to widely prescribed drugs might determine false positive UDS amphetamines, leading to diagnostic issues, wrong therapeutic choices, impairment of physician-patient relationship and legal implications.AREAS COVERED: To summarize and comment on a comprehensive list of compounds responsible for UDS false positive for amphetamines, we conducted a...
Source: Pharmacological Reviews - May 5, 2023 Category: Drugs & Pharmacology Authors: Vera Battini Giovanna Cirnigliaro Luca Giacovelli Maria Boscacci Silvia Massara Manzo Giulia Mosini Greta Guarnieri Michele Gringeri Beatrice Benatti Emilio Clementi Bernardo Dell'Osso Carla Carnovale Source Type: research
Psychiatric and non-psychiatric drugs causing false positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS
Expert Rev Clin Pharmacol. 2023 May 5. doi: 10.1080/17512433.2023.2211261. Online ahead of print.ABSTRACTINTRODUCTION: Immunoassay urine drug screen (UDS) is frequently used in clinical practice for initial screening process, being generally available, fast, and inexpensive. Exposure to widely prescribed drugs might determine false positive UDS amphetamines, leading to diagnostic issues, wrong therapeutic choices, impairment of physician-patient relationship and legal implications.AREAS COVERED: To summarize and comment on a comprehensive list of compounds responsible for UDS false positive for amphetamines, we conducted a...
Source: Expert Review of Clinical Pharmacology - May 5, 2023 Category: Drugs & Pharmacology Authors: Vera Battini Giovanna Cirnigliaro Luca Giacovelli Maria Boscacci Silvia Massara Manzo Giulia Mosini Greta Guarnieri Michele Gringeri Beatrice Benatti Emilio Clementi Bernardo Dell'Osso Carla Carnovale Source Type: research
Psychiatric and non-psychiatric drugs causing false positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS
Expert Rev Clin Pharmacol. 2023 May 5. doi: 10.1080/17512433.2023.2211261. Online ahead of print.ABSTRACTINTRODUCTION: Immunoassay urine drug screen (UDS) is frequently used in clinical practice for initial screening process, being generally available, fast, and inexpensive. Exposure to widely prescribed drugs might determine false positive UDS amphetamines, leading to diagnostic issues, wrong therapeutic choices, impairment of physician-patient relationship and legal implications.AREAS COVERED: To summarize and comment on a comprehensive list of compounds responsible for UDS false positive for amphetamines, we conducted a...
Source: Pharmacological Reviews - May 5, 2023 Category: Drugs & Pharmacology Authors: Vera Battini Giovanna Cirnigliaro Luca Giacovelli Maria Boscacci Silvia Massara Manzo Giulia Mosini Greta Guarnieri Michele Gringeri Beatrice Benatti Emilio Clementi Bernardo Dell'Osso Carla Carnovale Source Type: research
Psychiatric and non-psychiatric drugs causing false positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS
Expert Rev Clin Pharmacol. 2023 May 5. doi: 10.1080/17512433.2023.2211261. Online ahead of print.ABSTRACTINTRODUCTION: Immunoassay urine drug screen (UDS) is frequently used in clinical practice for initial screening process, being generally available, fast, and inexpensive. Exposure to widely prescribed drugs might determine false positive UDS amphetamines, leading to diagnostic issues, wrong therapeutic choices, impairment of physician-patient relationship and legal implications.AREAS COVERED: To summarize and comment on a comprehensive list of compounds responsible for UDS false positive for amphetamines, we conducted a...
Source: Expert Review of Clinical Pharmacology - May 5, 2023 Category: Drugs & Pharmacology Authors: Vera Battini Giovanna Cirnigliaro Luca Giacovelli Maria Boscacci Silvia Massara Manzo Giulia Mosini Greta Guarnieri Michele Gringeri Beatrice Benatti Emilio Clementi Bernardo Dell'Osso Carla Carnovale Source Type: research
Psychiatric and non-psychiatric drugs causing false positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS
Expert Rev Clin Pharmacol. 2023 May 5. doi: 10.1080/17512433.2023.2211261. Online ahead of print.ABSTRACTINTRODUCTION: Immunoassay urine drug screen (UDS) is frequently used in clinical practice for initial screening process, being generally available, fast, and inexpensive. Exposure to widely prescribed drugs might determine false positive UDS amphetamines, leading to diagnostic issues, wrong therapeutic choices, impairment of physician-patient relationship and legal implications.AREAS COVERED: To summarize and comment on a comprehensive list of compounds responsible for UDS false positive for amphetamines, we conducted a...
Source: Pharmacological Reviews - May 5, 2023 Category: Drugs & Pharmacology Authors: Vera Battini Giovanna Cirnigliaro Luca Giacovelli Maria Boscacci Silvia Massara Manzo Giulia Mosini Greta Guarnieri Michele Gringeri Beatrice Benatti Emilio Clementi Bernardo Dell'Osso Carla Carnovale Source Type: research
Psychiatric and non-psychiatric drugs causing false positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS
Expert Rev Clin Pharmacol. 2023 May 5. doi: 10.1080/17512433.2023.2211261. Online ahead of print.ABSTRACTINTRODUCTION: Immunoassay urine drug screen (UDS) is frequently used in clinical practice for initial screening process, being generally available, fast, and inexpensive. Exposure to widely prescribed drugs might determine false positive UDS amphetamines, leading to diagnostic issues, wrong therapeutic choices, impairment of physician-patient relationship and legal implications.AREAS COVERED: To summarize and comment on a comprehensive list of compounds responsible for UDS false positive for amphetamines, we conducted a...
Source: Expert Review of Clinical Pharmacology - May 5, 2023 Category: Drugs & Pharmacology Authors: Vera Battini Giovanna Cirnigliaro Luca Giacovelli Maria Boscacci Silvia Massara Manzo Giulia Mosini Greta Guarnieri Michele Gringeri Beatrice Benatti Emilio Clementi Bernardo Dell'Osso Carla Carnovale Source Type: research
