Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research

Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research

Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research

Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research

Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research

Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research

Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research

Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research

Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research

Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research

“There is nothing that can prevent me from supporting her:” men’s perspectives on their involvement and support of women’s use of topical therapy for cervical precancer treatment in Kenya
ConclusionThe use of self-administered topical therapies for cervical precancer treatment, if supported by efficacy studies in LMICs, may support achieving the WHO’s 2030 goal of 90% treatment access. We find that with adequate education, men express overwhelming support of their female partner’s use of topical therapies, including adherence to abstinence and contraception guidelines. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 12, 2024 Category: Cancer & Oncology Source Type: research

Malaria transmission heterogeneity in different eco-epidemiological areas of western Kenya: a region-wide observational and risk classification study for adaptive intervention planning
Understanding of malaria ecology is a prerequisite for designing locally adapted control strategies in resource-limited settings. The aim of this study was to utilize the spatial heterogeneity in malaria trans... (Source: Malaria Journal)
Source: Malaria Journal - March 12, 2024 Category: Infectious Diseases Authors: Guofa Zhou, John Githure, Ming-Chieh Lee, Daibin Zhong, Xiaoming Wang, Harrysone Atieli, Andrew K. Githeko, James Kazura and Guiyun Yan Tags: Research Source Type: research

Correction: Use of mobile technology to identify behavioral mechanisms linked to mental health outcomes in Kenya: protocol for development and validation of a predictive model
(Source: BMC Research Notes)
Source: BMC Research Notes - March 12, 2024 Category: Research Authors: Willie Njoroge, Rachel Maina, Elena Frank, Lukoye Atwoli, Zhenke Wu, Anthony K Ngugi, Srijan Sen, JianLi Wang, Stephen Wong, Jessica A Baker, Eileen M Weinheimer-Haus, Linda Khakali, Andrew Aballa, James Orwa, Moses K Nyongesa, Jasmit Shah & hellip; Tags: Correction Source Type: research

Quantifying health facility service readiness for small and sick newborn care: comparing standards-based and WHO level-2  + scoring for 64 hospitals implementing with NEST360 in Kenya, Malawi, Nigeria, and Tanzania
Service readiness tools are important for assessing hospital capacity to provide quality small and sick newborn care (SSNC). Lack of summary scoring approaches for SSNC service readiness means we are unable to... (Source: BMC Pediatrics)
Source: BMC Pediatrics - March 12, 2024 Category: Pediatrics Authors: Rebecca E. Penzias, Christine Bohne, Edith Gicheha, Elizabeth M. Molyneux, David Gathara, Samuel K. Ngwala, Evelyn Zimba, Ekran Rashid, Opeyemi Odedere, Olabisi Dosunmu, Robert Tillya, Josephine Shabani, James H. Cross, Christian Ochieng, Harriet H. Webst Tags: Research Source Type: research

Giant hepatic cyst
To the Editor: (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 11, 2024 Category: General Medicine Authors: Ai Yokoi, Kosuke Ishizuka, Iori Motohashi, Masaki Hiwatari, Takashi Asakura, Kenya Ie Tags: Clinical Communication to the Editor Source Type: research