Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research
Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research
Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research
Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research
Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research
Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research
Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research
Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research
Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research
Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research
Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research
Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research
Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: The American Journal of Tropical Medicine and Hygiene - March 12, 2024 Category: Tropical Medicine Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research
Targeted Testing and Treatment To Reduce Human Malaria Transmission in High-Risk Populations: A Systematic Review
Am J Trop Med Hyg. 2024 Mar 12:tpmd230097. doi: 10.4269/ajtmh.23-0097. Online ahead of print.ABSTRACTAs countries approach elimination of malaria, groups with increased exposure to malaria vectors or poor access to health services may serve as important human reservoirs of infection that help maintain transmission in the community. Parasitological testing and treatment targeted to these groups may reduce malaria transmission overall. This systematic review assessed the effectiveness of targeted testing and treatment (TTaT) to reduce malaria transmission, the contextual factors, and the results of modeling studies that esti...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Beena Bhamani Elisabet Mart í Coma-Cros Maria Tusell Vita Mithi Elisa Serra-Casas Nana Aba Williams Kim A Lindblade Koya C Allen Source Type: research
Short Report: Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
Am J Trop Med Hyg. 2024 Mar 12:tpmd230650. doi: 10.4269/ajtmh.23-0650. Online ahead of print.ABSTRACTAsymptomatic dengue virus (DENV) infections have important public health implications but are challenging to identify. We performed a cross-sectional study of reverse transcription quantitative polymerase chain reaction on pooled sera of asymptomatic individuals from the south coast of Kenya at two time periods to identify cases of asymptomatic viremia. Among 2,460 samples tested in pools of 9 or 10, we found only one positive case (0.04% incidence). Although pooling of samples has the potential to be a cost-effective and t...
Source: Am J Trop Med Hyg - March 12, 2024 Category: Infectious Diseases Authors: Melanie Kiener Nader Shayegh Sindiso Victor Nyathi Bryson Alberto Ndenga Francis Maluki Mutuku Angelle Desiree LaBeaud Source Type: research
