Kenyan adults with type 2 diabetes mellitus (T2DM): Increase diabetic knowledge and self-efficacy and decrease hemoglobina1c levels post-educational program
Conclusions: This study reveals the effect of a structured education intervention in increasing diabetic knowledge and self-efficacywhile reducing HbA1c levels in T2DM patients in Eldoret, Kenya.Keywords: Education program; type 2 diabetes; Kenya. (Source: African Health Sciences)
Source: African Health Sciences - April 8, 2024 Category: African Health Authors: Sabina Jeruto Bet, Jochebed Bosede Ade-Oshifogun Source Type: research

The impact of the COVID-19 pandemic on reproductive, maternal, neonatal, and child health care services in Kiambu County, Kenya
This study investigated the impact of COVID-19 on reproductive, maternal, neonatal, and child health (RMNCH) services in Kiambu County, Kenya. It was a retrospective cross-sectional study, where data on antenatal care (ANC), delivery, postnatal care (PNC), and family planning (FP) before and after COVID-19 was retrieved and compared. New ANC clients and 4th ANC visits decreased by 2.9% and 17% respectively. New clients attending PNC increased by 13.3% (p = 0.007). Skilled deliveries reduced by 0.3%, maternal, neonatal deaths, and fresh stillbirths reduced by 0.7%, 23.9%, and 15.8% respectively. Caesarean sections rose by 1...
Source: African Journal of Reproductive Health - April 7, 2024 Category: African Health Authors: Davis Kamondo Magoma Mwancha-Kwasa Moses Kamita Caroline Mwangi Maxwell Murage Prabhjot K Juttla Daniel Gicheru Jesse Gitaka Source Type: research

A phase IIa, randomized, double-blind, safety, immunogenicity and efficacy trial of Plasmodium falciparum vaccine antigens merozoite surface protein 1 and RTS,S formulated with AS02 adjuvant in healthy, malaria-na ïve adults
CONCLUSION: Co-administration of RTS,S and FMP1/AS02 reduced anti-RTS,S antibody, but did not affect tolerability, cellular immunity, or efficacy in a stringent CHMI model. Absence of efficacy or delay of patency in the sporozoite challenge model in the FMP1/AS02 group did not rule out efficacy of FMP1/AS02 in an endemic population. However, a Phase IIb trial of FMP1/AS02 in children in malaria-endemic Kenya did not demonstrate efficacy against natural infection.CLINICALTRIALS: gov identifier: NCT01556945.PMID:38584058 | DOI:10.1016/j.vaccine.2024.03.072 (Source: Vaccine)
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: J F Cummings M E Polhemus K E Kester C F Ockenhouse R A Gasser P Coyne G Wortmann R K Nielsen K Schaecher C A Holland U Krzych N Tornieporth L A Soisson E Angov D G Heppner RTS,S Vaccine Evaluation Group Source Type: research

The impact of the COVID-19 pandemic on reproductive, maternal, neonatal, and child health care services in Kiambu County, Kenya
This study investigated the impact of COVID-19 on reproductive, maternal, neonatal, and child health (RMNCH) services in Kiambu County, Kenya. It was a retrospective cross-sectional study, where data on antenatal care (ANC), delivery, postnatal care (PNC), and family planning (FP) before and after COVID-19 was retrieved and compared. New ANC clients and 4th ANC visits decreased by 2.9% and 17% respectively. New clients attending PNC increased by 13.3% (p = 0.007). Skilled deliveries reduced by 0.3%, maternal, neonatal deaths, and fresh stillbirths reduced by 0.7%, 23.9%, and 15.8% respectively. Caesarean sections rose by 1...
Source: African Journal of Reproductive Health - April 7, 2024 Category: African Health Authors: Davis Kamondo Magoma Mwancha-Kwasa Moses Kamita Caroline Mwangi Maxwell Murage Prabhjot K Juttla Daniel Gicheru Jesse Gitaka Source Type: research

A phase IIa, randomized, double-blind, safety, immunogenicity and efficacy trial of Plasmodium falciparum vaccine antigens merozoite surface protein 1 and RTS,S formulated with AS02 adjuvant in healthy, malaria-na ïve adults
CONCLUSION: Co-administration of RTS,S and FMP1/AS02 reduced anti-RTS,S antibody, but did not affect tolerability, cellular immunity, or efficacy in a stringent CHMI model. Absence of efficacy or delay of patency in the sporozoite challenge model in the FMP1/AS02 group did not rule out efficacy of FMP1/AS02 in an endemic population. However, a Phase IIb trial of FMP1/AS02 in children in malaria-endemic Kenya did not demonstrate efficacy against natural infection.CLINICALTRIALS: gov identifier: NCT01556945.PMID:38584058 | DOI:10.1016/j.vaccine.2024.03.072 (Source: Vaccine)
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: J F Cummings M E Polhemus K E Kester C F Ockenhouse R A Gasser P Coyne G Wortmann R K Nielsen K Schaecher C A Holland U Krzych N Tornieporth L A Soisson E Angov D G Heppner RTS,S Vaccine Evaluation Group Source Type: research

The impact of the COVID-19 pandemic on reproductive, maternal, neonatal, and child health care services in Kiambu County, Kenya
This study investigated the impact of COVID-19 on reproductive, maternal, neonatal, and child health (RMNCH) services in Kiambu County, Kenya. It was a retrospective cross-sectional study, where data on antenatal care (ANC), delivery, postnatal care (PNC), and family planning (FP) before and after COVID-19 was retrieved and compared. New ANC clients and 4th ANC visits decreased by 2.9% and 17% respectively. New clients attending PNC increased by 13.3% (p = 0.007). Skilled deliveries reduced by 0.3%, maternal, neonatal deaths, and fresh stillbirths reduced by 0.7%, 23.9%, and 15.8% respectively. Caesarean sections rose by 1...
Source: African Journal of Reproductive Health - April 7, 2024 Category: African Health Authors: Davis Kamondo Magoma Mwancha-Kwasa Moses Kamita Caroline Mwangi Maxwell Murage Prabhjot K Juttla Daniel Gicheru Jesse Gitaka Source Type: research

A phase IIa, randomized, double-blind, safety, immunogenicity and efficacy trial of Plasmodium falciparum vaccine antigens merozoite surface protein 1 and RTS,S formulated with AS02 adjuvant in healthy, malaria-na ïve adults
CONCLUSION: Co-administration of RTS,S and FMP1/AS02 reduced anti-RTS,S antibody, but did not affect tolerability, cellular immunity, or efficacy in a stringent CHMI model. Absence of efficacy or delay of patency in the sporozoite challenge model in the FMP1/AS02 group did not rule out efficacy of FMP1/AS02 in an endemic population. However, a Phase IIb trial of FMP1/AS02 in children in malaria-endemic Kenya did not demonstrate efficacy against natural infection.CLINICALTRIALS: gov identifier: NCT01556945.PMID:38584058 | DOI:10.1016/j.vaccine.2024.03.072 (Source: Vaccine)
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: J F Cummings M E Polhemus K E Kester C F Ockenhouse R A Gasser P Coyne G Wortmann R K Nielsen K Schaecher C A Holland U Krzych N Tornieporth L A Soisson E Angov D G Heppner RTS,S Vaccine Evaluation Group Source Type: research

The impact of the COVID-19 pandemic on reproductive, maternal, neonatal, and child health care services in Kiambu County, Kenya
This study investigated the impact of COVID-19 on reproductive, maternal, neonatal, and child health (RMNCH) services in Kiambu County, Kenya. It was a retrospective cross-sectional study, where data on antenatal care (ANC), delivery, postnatal care (PNC), and family planning (FP) before and after COVID-19 was retrieved and compared. New ANC clients and 4th ANC visits decreased by 2.9% and 17% respectively. New clients attending PNC increased by 13.3% (p = 0.007). Skilled deliveries reduced by 0.3%, maternal, neonatal deaths, and fresh stillbirths reduced by 0.7%, 23.9%, and 15.8% respectively. Caesarean sections rose by 1...
Source: African Journal of Reproductive Health - April 7, 2024 Category: African Health Authors: Davis Kamondo Magoma Mwancha-Kwasa Moses Kamita Caroline Mwangi Maxwell Murage Prabhjot K Juttla Daniel Gicheru Jesse Gitaka Source Type: research