Development of the hematopoietic system: expanding the concept of hematopoietic stem cell-independent hematopoiesis
Trends Cell Biol. 2023 Jul 20:S0962-8924(23)00130-7. doi: 10.1016/j.tcb.2023.06.007. Online ahead of print.ABSTRACTHematopoietic stem cells (HSCs) give rise to nearly all blood cell types and play a central role in blood cell production in adulthood. For many years it was assumed that these roles were similarly responsible for driving the formation of the hematopoietic system during the embryonic period. However, detailed analysis of embryonic hematopoiesis has revealed the presence of hematopoietic cells that develop independently of HSCs both before and after HSC generation. Furthermore, it is becoming increasingly clear...
Source: Trends in Cell Biology - July 22, 2023 Category: Cytology Authors: Tomomasa Yokomizo Toshio Suda Source Type: research

Development of the hematopoietic system: expanding the concept of hematopoietic stem cell-independent hematopoiesis
Trends Cell Biol. 2023 Jul 20:S0962-8924(23)00130-7. doi: 10.1016/j.tcb.2023.06.007. Online ahead of print.ABSTRACTHematopoietic stem cells (HSCs) give rise to nearly all blood cell types and play a central role in blood cell production in adulthood. For many years it was assumed that these roles were similarly responsible for driving the formation of the hematopoietic system during the embryonic period. However, detailed analysis of embryonic hematopoiesis has revealed the presence of hematopoietic cells that develop independently of HSCs both before and after HSC generation. Furthermore, it is becoming increasingly clear...
Source: Trends in Cell Biology - July 22, 2023 Category: Cytology Authors: Tomomasa Yokomizo Toshio Suda Source Type: research

Development of the hematopoietic system: expanding the concept of hematopoietic stem cell-independent hematopoiesis
Trends Cell Biol. 2023 Jul 20:S0962-8924(23)00130-7. doi: 10.1016/j.tcb.2023.06.007. Online ahead of print.ABSTRACTHematopoietic stem cells (HSCs) give rise to nearly all blood cell types and play a central role in blood cell production in adulthood. For many years it was assumed that these roles were similarly responsible for driving the formation of the hematopoietic system during the embryonic period. However, detailed analysis of embryonic hematopoiesis has revealed the presence of hematopoietic cells that develop independently of HSCs both before and after HSC generation. Furthermore, it is becoming increasingly clear...
Source: Trends in Cell Biology - July 22, 2023 Category: Cytology Authors: Tomomasa Yokomizo Toshio Suda Source Type: research

Development of the hematopoietic system: expanding the concept of hematopoietic stem cell-independent hematopoiesis
Trends Cell Biol. 2023 Jul 20:S0962-8924(23)00130-7. doi: 10.1016/j.tcb.2023.06.007. Online ahead of print.ABSTRACTHematopoietic stem cells (HSCs) give rise to nearly all blood cell types and play a central role in blood cell production in adulthood. For many years it was assumed that these roles were similarly responsible for driving the formation of the hematopoietic system during the embryonic period. However, detailed analysis of embryonic hematopoiesis has revealed the presence of hematopoietic cells that develop independently of HSCs both before and after HSC generation. Furthermore, it is becoming increasingly clear...
Source: Trends in Cell Biology - July 22, 2023 Category: Cytology Authors: Tomomasa Yokomizo Toshio Suda Source Type: research

Development of the hematopoietic system: expanding the concept of hematopoietic stem cell-independent hematopoiesis
Trends Cell Biol. 2023 Jul 20:S0962-8924(23)00130-7. doi: 10.1016/j.tcb.2023.06.007. Online ahead of print.ABSTRACTHematopoietic stem cells (HSCs) give rise to nearly all blood cell types and play a central role in blood cell production in adulthood. For many years it was assumed that these roles were similarly responsible for driving the formation of the hematopoietic system during the embryonic period. However, detailed analysis of embryonic hematopoiesis has revealed the presence of hematopoietic cells that develop independently of HSCs both before and after HSC generation. Furthermore, it is becoming increasingly clear...
Source: Trends in Cell Biology - July 22, 2023 Category: Cytology Authors: Tomomasa Yokomizo Toshio Suda Source Type: research