Pre-sternal thyroid swellings: a case of rare aberrant site recurrence and review of literature
ConclusionPre-sternal region masses of thyroid origin are very rare. A proper work up, suspicion for thyroid mass and array of tests will be required to come to a provisional diagnosis. Since the masses reported in literature were primarily malignant, any such mass may be treated on lines of malignancy with radical surgery. (Source: Thyroid Research)
Source: Thyroid Research - November 20, 2019 Category: Endocrinology Source Type: research
Meeting Abstracts from the 67 th Annual British Thyroid Association Meeting
(Source: Thyroid Research)
Source: Thyroid Research - November 18, 2019 Category: Endocrinology Source Type: research
The surgical management of locally advanced well-differentiated thyroid carcinoma: changes over the years according to the AJCC 8th edition Cancer Staging Manual
ConclusionsWe discuss the changes introduced by the 8th edition AJCC Cancer Staging Manual, in terms of the diagnostic and surgical management of extra thyroid extension, in patients affected by papillary and follicular thyroid cancer. (Source: Thyroid Research)
Source: Thyroid Research - October 26, 2019 Category: Endocrinology Source Type: research
Association of thyroid hormones with resting energy expenditure and complement C3 in normal weight high body fat women
ConclusionAn increase in body fat even in the presence of a normal body weight can be accompanied by the changes in thyroid function and inflammatory markers such as complement C3. (Source: Thyroid Research)
Source: Thyroid Research - October 24, 2019 Category: Endocrinology Source Type: research
Painless destructive thyroiditis in a patient with resistance to thyroid hormone: a case report
ConclusionThe present case demonstrates that diagnosing RTH is difficult when patients show hyperthyroxinemia with complete suppression of TSH to undetectable levels, and the data lead to misdiagnosis of RTH as Graves ’ disease. The initial diagnosis is important, and Tc-99 m scintigraphy is useful for the differential diagnosis of thyrotoxicosis accompanying RTH. (Source: Thyroid Research)
Source: Thyroid Research - October 24, 2019 Category: Endocrinology Source Type: research
Genomic test ends a long diagnostic odyssey in a patient with resistance to thyroid hormones
ConclusionsThyroid hormone resistance continues to be an un(der)- and misdiagnosed thyroid condition whose management is particularly challenging when associated with autoimmune thyroid disease. Whole exome sequencing has the potential to identifyTHRB pathogenic variants as incidental findings. Reporting such secondary findings from genomic testing may be particularly important in the context of the rarity of the condition and the potential clinical consequences of misdiagnosis and mistreatment. (Source: Thyroid Research)
Source: Thyroid Research - July 14, 2019 Category: Endocrinology Source Type: research
Association of antithyroglobulin antibody with iodine nutrition and thyroid dysfunction in Nepalese children
ConclusionsSchool children of eastern Nepal have adequate iodine nutrition. Thyroid autoimmunity is very common, while thyroid dysfunction is sparse in children. An association of thyroid autoimmunity with iodine nutrition and thyroid dysfunction was seen in children. (Source: Thyroid Research)
Source: Thyroid Research - July 8, 2019 Category: Endocrinology Source Type: research
Levothyroxine before conception in women with thyroid antibodies: a step forward in the management of thyroid disease in pregnancy
AbstractStudies suggesting an association between thyroid autoimmunity and pregnancy-related adverse outcomes, particularly miscarriage and preterm delivery, date to nineties. The postulated causes for these associations were attributed to a direct or indirect effect of autoimmunity and/or to a mild thyroid impairment.Since then, small trials and several meta-analyses confirmed a detrimental effect of thyroid autoimmunity and suggested that patients with thyroid autoimmunity who wish to conceive or are pregnant might benefit from levothyroxine treatment to decrease the rate of miscarriage and preterm delivery.A recently pu...
Source: Thyroid Research - June 19, 2019 Category: Endocrinology Source Type: research
Semi-quantitative assessment of diffuse hepatic uptake seen in I-131 scans – an indicator of functioning thyroid tissue and disease burden in differentiated thyroid cancer
ConclusionHTR has good correlation with functional status of tumor cells, while it has weak correlation to therapeutic dose of I-131 administered and serum Tg. Increased HTR predicts significant disease burden in the form of distant bone and lung metastasis and may potentially be used as a second prognostic factor apart from serum Tg. (Source: Thyroid Research)
Source: Thyroid Research - April 24, 2019 Category: Endocrinology Source Type: research
Normalization of thyroid function tests among thyrotoxicosis patients attending a University Hospital in North-West Ethiopia
ConclusionThough PTU is not the preferred antithyroid agent in the management of thyrotoxicosis, all patients used PTU for the management of hyperthyroidism. All TFTs were normalized in only less than one-third of the participants. Resolution of symptoms took longer period of time than expected. (Source: Thyroid Research)
Source: Thyroid Research - March 22, 2019 Category: Endocrinology Source Type: research
Hypothyroidism in the older population
ConclusionsCurrent evidence suggests that threshold for treating mild subclinical hypothyroidism in older people should be high. It is reasonable to aim for a higher TSH target in treated older hypothyroid patients as their thyroid hormone requirements may be lower. In addition, age-appropriate TSH reference ranges should be considered in the diagnostic pathway of identifying individuals at risk of developing hypothyroidism. Appropriately designed and powered randomised controlled trials are required to confirm risk/benefit of treatment of subclinical hypothyroidism in older people. Until the results of such RCTs are avail...
Source: Thyroid Research - February 8, 2019 Category: Endocrinology Source Type: research
Mucin in benign thyroid nodules: treatment related change or not?
(Source: Thyroid Research)
Source: Thyroid Research - January 11, 2019 Category: Endocrinology Source Type: research
Thyroid malignancy among patients with thyroid nodules in the United Arab Emirates: a five-year retrospective tertiary Centre analysis
ConclusionWe report a higher prevalence of thyroid malignancy among patients with thyroid nodules relative to that reported in other parts of the world. The rate of thyroid malignancy was higher in patients of Far-East Asian and Caucasian ethnic background. (Source: Thyroid Research)
Source: Thyroid Research - November 30, 2018 Category: Endocrinology Source Type: research
Rapid detection of papillary thyroid carcinoma by fluorescence imaging using a γ-glutamyltranspeptidase-specific probe: a pilot study
ConclusionsAll PTC samples were detected by fluorescence imaging with gGlu-HMRG. Thus, fluorescence imaging with gGlu-HMRG is a rapid, simple, and powerful detection tool for PTC. (Source: Thyroid Research)
Source: Thyroid Research - November 21, 2018 Category: Endocrinology Source Type: research
Calcitonin measurement in fine-needle aspirate washout fluid by electrochemiluminescence immunoassay for thyroid tumors
ConclusionsThis is the first study to determine the cut-off value of FNA-Ct with an ECLIA, and we propose that the optimal cut-off value is 21.0 pg/mL. (Source: Thyroid Research)
Source: Thyroid Research - October 30, 2018 Category: Endocrinology Source Type: research
