Abstracts from the 71st Annual Meeting of the British Thyroid Association
(Source: Thyroid Research)
Source: Thyroid Research - July 11, 2023 Category: Endocrinology Source Type: research
Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the design of the WaTCh study
AbstractBackgroundThyroid cancer (TC) patients are understudied but appear to be at risk for poor physical and psychosocial outcomes. Knowledge of the course and determinants of these deteriorated outcomes is lacking. Furthermore, little is known about mediating biological mechanisms.ObjectivesThe WaTCh-study aims to;Examine the course of physical and psychosocial outcomes.Examine the association of demographic, environmental, clinical, physiological, and personality characteristics to those outcomes. In other words,who is at risk?Reveal the association of mediating biological mechanisms (inflammation, kynurenine pathway) ...
Source: Thyroid Research - July 10, 2023 Category: Endocrinology Source Type: research
A study to evaluate association of nuclear grooving in benign thyroid lesions with RET/PTC1 and RET/PTC3 gene translocation
ConclusionsThe frequency of nuclear grooving among BTLs in our study was 36.8%. Our study shows, that when BTLs, show nuclear grooves, with an increase in the nuclear size, oval and elongated shape, favors the possibility of an underlying genetic aberration like RET/PTC gene translocation, which in turn supports the reporting pathologist to suggest a close follow up of the patients on seeing such nuclear features on cytology or histopathology sample, particularly in HT. (Source: Thyroid Research)
Source: Thyroid Research - July 3, 2023 Category: Endocrinology Source Type: research
Hypokalemic periodic paralysis as the first sign of thyrotoxicosis- a rare case report from Somalia
ConclusionTo prevent life-threatening cardiac and respiratory complications, it is critical to consider and diagnose THPP early, even in populations where the condition is rare. (Source: Thyroid Research)
Source: Thyroid Research - June 12, 2023 Category: Endocrinology Source Type: research
Primary leiomyosarcoma of the thyroid with concurrent papillary thyroid cancer: a rare case report and a review of literature
ConclusionThyroid LMS is a rare malignancy with a worse prognosis than PTC. A thorough workup must be done to rule out metastasis before labeling it as primary thyroid cancer. (Source: Thyroid Research)
Source: Thyroid Research - June 5, 2023 Category: Endocrinology Source Type: research
Effect of morning versus night-time administration of proton pump inhibitor (pantoprazole) on thyroid function test in levothyroxine-treated primary hypothyroidism: a prospective cross-over study
ConclusionsConcomitant use of pantoprazole, even for 6 weeks, leads to significant elevation in serum TSH in levothyroxine-treated patients who are biochemically euthyroid, irrespective of timing of pantoprazole intake. Early morning and night-time administration of pantoprazole have similar effect on TFT in these patients. (Source: Thyroid Research)
Source: Thyroid Research - June 1, 2023 Category: Endocrinology Source Type: research
Correction to: Age-related variation in thyroid function – a narrative review highlighting important implications for research and clinical practice
(Source: Thyroid Research)
Source: Thyroid Research - May 30, 2023 Category: Endocrinology Source Type: research
Human exposure to pesticides and thyroid cancer: a worldwide systematic review of the literatures
AbstractThyroid cancer is considered as one of the most prevalent cancers in the world. Some pesticides can play a role as a potentially important risk factor in thyroid cancer by affecting thyroid morphology and thyroid hormone homeostasis. The aim of present study was to systematically review the available epidemiological evidence for human exposure to pesticides and thyroid cancer. Articles were searched in PubMed, Scopus and Web of Science by suitable keywords from January 2000 to May 2021. Standard techniques for systematic reviews were followed in the current study and results reported according to Preferred Reportin...
Source: Thyroid Research - May 15, 2023 Category: Endocrinology Source Type: research
Correction to: Solitary and multiple thyroid nodules as predictors of malignancy: a systematic review and meta ‑analysis
(Source: Thyroid Research)
Source: Thyroid Research - May 8, 2023 Category: Endocrinology Source Type: research
Analysis of 665 thyroid nodules using both EU-TIRADS and ACR TI-RADS classification systems
ConclusionsThe EU-TIRADS and ACR TI-RADS are both suitable to assess thyroid nodules and through risk stratification avoid unnecessary FNA. FNA was less performed using ACR TI-RADS, which was slightly more efficiency in excluding malignancy. (Source: Thyroid Research)
Source: Thyroid Research - May 8, 2023 Category: Endocrinology Source Type: research
Thyrotoxic periodic paralysis in a Caucasian man without identifiable genetic predisposition: a case report
ConclusionTPP is very rare in Caucasians but more often affects young men in East Asian populations. The case presents a Caucasian man with TPP where genetic testing ofCACNA1S,KCNJ18,SCN4A,KCNJ2,KCNE3, andABCC8 shows no pathogenic variants in genes previously associated with TPP. (Source: Thyroid Research)
Source: Thyroid Research - May 1, 2023 Category: Endocrinology Source Type: research
Hyperthyroidism in pregnancy: design and methodology of a Danish multicenter study
ConclusionThis report describes a newly established systematic and nationwide collection of detailed clinical data on pregnant women with hyperthyroidism and their offspring. Considering the course and relatively low prevalence of GD in pregnant women, such nationwide design is essential to establish a sufficiently large cohort. (Source: Thyroid Research)
Source: Thyroid Research - April 12, 2023 Category: Endocrinology Source Type: research
Colorectal cancer metastases in thyroid: case report and literature review
ConclusionsColorectal adenocarcinoma metastases can rarely present as a metastatic thyroid nodule. Fine-needle aspiration should be performed in suspicious thyroid nodules and may be the least invasive way of identifying a metastatic colorectal or other non-thyroidal malignancy in patients presenting with an unknown primary. The pathologist should be vigilant to this possibility and specific immunohistochemical markers should be used to ensure accurate diagnosis.In thyroid metastases, the prognosis is ultimately determined by the primary tumour but thyroidectomy still has a role in alleviating compressive symptoms and can ...
Source: Thyroid Research - April 10, 2023 Category: Endocrinology Source Type: research
Age-related variation in thyroid function – a narrative review highlighting important implications for research and clinical practice
ConclusionThyroid hormone reference intervals have differential effects across age groups. Current reference ranges could potentially lead to inappropriate treatment in older individuals but on the other hand could result in missed opportunities for risk factor modification in the younger and middle-aged groups. Further studies are now needed to determine the validity of age-appropriate reference intervals and to understand the impact of thyroid hormone variations in younger individuals. (Source: Thyroid Research)
Source: Thyroid Research - April 3, 2023 Category: Endocrinology Source Type: research
Screening for thyroid disease in pregnancy: a study of Danish clinical practice
ConclusionIn a Danish regional investigation, 1 in 4 women had their thyroid function tested in relation to a pregnancy. However, recommended risk-based screening criteria for thyroid disease in pregnancy were heterogeneously distributed. Results encourage considerations on the current practice for the screening of thyroid function in Danish pregnant women and inform the general debate. (Source: Thyroid Research)
Source: Thyroid Research - March 31, 2023 Category: Endocrinology Source Type: research
