Increased soluble IL-2 receptor levels in serum from a patient with painless thyroiditis
Conclusion
There was no evidence of relapse of the malignant lymphoma. We conclude that the increase of sIL-2R was associated with painless thyroiditis. Considering the similar time-course between the reduction of serum sIL-2R and those of AST and ALT, which are often accompanied by autoimmune processes in painless thyroiditis during the development of hyperthyroidism, it was suggested that the increase of serum sIL-2R in this case resulted from activation of an autoimmune process. (Source: Thyroid Research)
Source: Thyroid Research - December 5, 2013 Category: Endocrinology Source Type: research
Negative correlation between bone mineral density and TSH receptor antibodies in long-term euthyroid postmenopausal women with treated Graves’ disease
Conclusions
In euthyroid women with a history of Graves’ hyperthyroidism, BMD was only affected in the postmenopausal group. The negative correlation of Z-score of lumbar spine BMD with TRAb suggests that this antibody may affect the bone metabolism. (Source: Thyroid Research)
Source: Thyroid Research - September 11, 2013 Category: Endocrinology Source Type: research
Potassium iodide, but not potassium iodate, as a potential protective agent against oxidative damage to membrane lipids in porcine thyroid
Conclusions
Potassium iodide, used in doses generally recommended in iodide prophylaxis, may prevent oxidative damage to membrane lipids in this gland. Toxic effects of iodide overload may result from its prooxidative action. Potassium iodate does not possess any direct beneficial effects on oxidative damage to membrane lipids in the thyroid, which constitutes an additional argument against its utility in iodine prophylaxis. (Source: Thyroid Research)
Source: Thyroid Research - August 30, 2013 Category: Endocrinology Source Type: research
Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin-1
Conclusions
Our data reveal a significant and sustained increase in serum adiponectin, as well as possible decrease of free MMP-9 concentration after radioiodine administration. In contrast, there was no significant change of TSP-1. This might indicate overall safety of radioiodine treatment of thyrotoxicosis in terms of the risks of subsequent cardiovascular and neoplastic disease. (Source: Thyroid Research)
Source: Thyroid Research - August 6, 2013 Category: Endocrinology Source Type: research
TSH receptor antibodies have predictive value for breast cancer – retrospective analysis
Conclusions
The strong relationship between Graves’ disease and breast cancer is proposed. We suggest that TSHRAb could be described as a positive determinant of breast cancer. The present data call attention to the usefulness of screening for breast cancer in long-term follow-up of patients with autoimmune thyroid disorders, especially of those with Graves’ disease. Similarly, screening for autoimmune thyroid disorders should be performed in patients with nodular breast disease. Additionally, the article draws ideas for further research in order to develop targeted treatment for more successful o...
Source: Thyroid Research - May 16, 2013 Category: Endocrinology Source Type: research
A solitary hyperfunctioning thyroid nodule harboring thyroid carcinoma: review of the literature
Abstract
Hyperfunctioning nodules of the thyroid are thought to only rarely harbor thyroid cancer, and thus are infrequently biopsied. Here, we present the case of a patient with a hyperfunctioning thyroid nodule harboring thyroid carcinoma and, using MEDLINE literature searches, set out to determine the prevalence of and characteristics of malignant “hot” nodules as a group. Historical, biochemical and radiologic characteristics of the case subjects and their nodules were compared to those in cases of benign hyperfunctioning nodules. A literature review of surgical patients with solitary hyperfunct...
Source: Thyroid Research - May 4, 2013 Category: Endocrinology Source Type: research
Proposed algorithm for management of patients with thyroid nodules/focal lesions, based on ultrasound (US) and fine-needle aspiration biopsy (FNAB); our own experience
Conclusion
Complementary use of our scoring system and FNAB TBSRTC categories can help to make optimal clinical decisions as regards the selection of treatment strategy. (Source: Thyroid Research)
Source: Thyroid Research - April 20, 2013 Category: Endocrinology Source Type: research
Odd thyroid function tests results: interference versus non-compliance
(Source: Thyroid Research)
Source: Thyroid Research - April 5, 2013 Category: Endocrinology Source Type: research
Interactions of metabolic syndrome and thyroid hormones
(Source: Thyroid Research)
Source: Thyroid Research - April 5, 2013 Category: Endocrinology Source Type: research
Thyroid hormones and male reproductive system
(Source: Thyroid Research)
Source: Thyroid Research - April 5, 2013 Category: Endocrinology Source Type: research
MicroRNAs in thyroid function and pathology
(Source: Thyroid Research)
Source: Thyroid Research - April 5, 2013 Category: Endocrinology Source Type: research
Curiosa in fine needle aspiration biopsy of the thyroid gland
(Source: Thyroid Research)
Source: Thyroid Research - April 5, 2013 Category: Endocrinology Source Type: research
