Correlation between anti-thyroid peroxidase antibody levels and diffuse thyroid uptake of 18 F-fluorodeoxyglucose in Hashimoto ’s thyroiditis: a retrospective study
ConclusionsThe results of the current study suggest that Hashimoto ’s thyroiditis patients with high titers of anti-thyroid antibodies are likely to exhibit intense diffuse FDG uptake in the thyroid, and that thyroid function may be clearly impaired, even in the presence of mild FDG uptake in the thyroid. (Source: Thyroid Research)
Source: Thyroid Research - October 16, 2018 Category: Endocrinology Source Type: research
Synergistic inhibition of MEK/ERK and BRAF V600E with PD98059 and PLX4032 induces sodium/iodide symporter (NIS) expression and radioiodine uptake in BRAF mutated papillary thyroid cancer cells
ConclusionSimultaneously suppressing BRAF V600E and p-ERK restored NIS expression and increase Iodide uptake in PTC cells, which was associated the inhibition of p-ERK expression. The results warrants clinical trials to confirm. (Source: Thyroid Research)
Source: Thyroid Research - October 11, 2018 Category: Endocrinology Source Type: research
Hyperthyroidism in a complete molar pregnancy with a mature cystic ovarian teratoma
ConclusionThis case presents the rare occurrence of a complete hydatidiform mole causing hyperthyroidism and an associated finding of a mature cystic teratoma. It also highlights the importance of monitoring b-hCG levels following a complete molar pregnancy due to an increased risk of choriocarcinoma. (Source: Thyroid Research)
Source: Thyroid Research - August 10, 2018 Category: Endocrinology Source Type: research
A rare malignant thyroid carcinosarcoma with aggressive behavior and DICER1 gene mutation: a case report with literature review
ConclusionTo our knowledge, the E1705K point mutation within theDICER1 gene is the first reported mutation in carcinosarcoma of the thyroid. A comprehensive review of the relevant literature is also included for discussion. (Source: Thyroid Research)
Source: Thyroid Research - July 31, 2018 Category: Endocrinology Source Type: research
The largest reported papillary thyroid carcinoma arising in struma ovarii and metastasis to opposite ovary: case report and review of literature
ConclusionsAmong the different surgeries for MSO, TAH + BSO appears to have the best clinical outcome. However, unilateral salpingo-oopherectomy/ unilateral oophorectomy and bilateral salpingo-oopherectomy also seem effective. Ovarian cystectomy alone seems associated with higher recurrence. There remains no consensus on the associations between M SO tumor size and potential extent of metastasis, and about the management of thyroid gland. However, surveillance and thyroid gland work up to detect concurrent thyroid cancer are recommended. (Source: Thyroid Research)
Source: Thyroid Research - July 24, 2018 Category: Endocrinology Source Type: research
Effect of perchlorate and thiocyanate exposure on thyroid function of pregnant women from South-West England: a cohort study
ConclusionEnvironmental perchlorate exposure is negatively associated with circulating FT4 levels in third trimester pregnant women. This may have an adverse impact on neurocognitive development of the fetus. (Source: Thyroid Research)
Source: Thyroid Research - July 6, 2018 Category: Endocrinology Source Type: research
‘Does levothyroxine improve pregnancy outcomes in euthyroid women with thyroid autoimmunity undergoing assisted reproductive technology?’
AbstractEvidence on the treatment of euthyroid infertile women and thyroid autoimmunity with thyroid hormone is scare, and therefore the recent study by Wang et al. is a welcome addition to it. Based on their results, thyroid hormone seems not to be indicated to decrease the miscarriage rate in that particular group of infertile women. This comment is meant to put the study results into perspective with the available evidence and the current guidelines, and to highlight its strengths and weaknesses. (Source: Thyroid Research)
Source: Thyroid Research - May 30, 2018 Category: Endocrinology Source Type: research
Characteristics and natural course of hypoechoic thyroid lesions diagnosed as possible thyroid lymphomas by fine needle aspiration cytology
ConclusionsOur study suggests that some hypoechoic thyroid lesions that are possible thyroid lymphoma based on US and FNAC might decrease in size or disappear during the careful observation. (Source: Thyroid Research)
Source: Thyroid Research - May 30, 2018 Category: Endocrinology Source Type: research
‘Does levothyroxine improve pregnancy outcomes in euthyroid women with thyroid autoimmunity undergoing assisted reproductive technology?’
AbstractEvidence on the treatment of euthyroid infertile women and thyroid autoimmunity with thyroid hormone is scare, and therefore the recent study by Wang et al. is a welcome addition to it. Based on their results, thyroid hormone seems not to be indicated to decrease the miscarriage rate in that particular group of infertile women. This comment is meant to put the study results into perspective with the available evidence and the current guidelines, and to highlight its strengths and weaknesses. (Source: Thyroid Research)
Source: Thyroid Research - May 30, 2018 Category: Endocrinology Source Type: research
Characteristics and natural course of hypoechoic thyroid lesions diagnosed as possible thyroid lymphomas by fine needle aspiration cytology
ConclusionsOur study suggests that some hypoechoic thyroid lesions that are possible thyroid lymphoma based on US and FNAC might decrease in size or disappear during the careful observation. (Source: Thyroid Research)
Source: Thyroid Research - May 30, 2018 Category: Endocrinology Source Type: research
Thyroid hormones increase stomach goblet cell numbers and mucin expression during indomethacin induced ulcer healing in Wistar rats
ConclusionThis study confirms the role played by thyroid hormones in healing of indomethacin induced gastric ulcers. The study further demonstrates increased numbers of both neutral and acidic goblet cells and the increase in expression of both neutral and acidic mucins during healing of indomethacin induced ulcers. (Source: Thyroid Research)
Source: Thyroid Research - May 25, 2018 Category: Endocrinology Source Type: research
