Evaluation of anti-M üllerian hormone in pre-menopausal women stratified according to thyroid function, autoimmunity and age
ConclusionsIn our cohort of women, age proved to be a better predictor of AMH levels than any of the other factors linked to thyroid function and autoimmunity. Our data do not support the hypothesis that subclinical hypothyroidism and/or autoimmunity are associated with decreased ovarian reserve. However, a larger number of cases is needed in order to obtain conclusive data. (Source: Thyroid Research)
Source: Thyroid Research - August 15, 2022 Category: Endocrinology Source Type: research
Management of malignant struma ovarii: is aggressive therapy justified? Case report and literature review
ConclusionsEven if latest literature reports consider that completion of local surgery with total thyroidectomy and RAI might be too aggressive in cases of MSO without extraovarian extension, in our case it was decided to follow the protocol for primary thyroid carcinoma, in order to reduce the recurrence risk. (Source: Thyroid Research)
Source: Thyroid Research - August 11, 2022 Category: Endocrinology Source Type: research
Extrathyroidal extension and cervical node infiltration are associated with recurrences and shorter recurrence-free survival in differentiated thyroid cancer: a cohort study
ConclusionRecurrence rates in our study population are relatively high. Extrathyroidal extension, positive neck lymph node, and older age were associated with recurrence risks of well differentiated thyroid cancers. (Source: Thyroid Research)
Source: Thyroid Research - July 26, 2022 Category: Endocrinology Source Type: research
Meeting Abstracts from the 70th Annual British Thyroid Association Meeting
(Source: Thyroid Research)
Source: Thyroid Research - July 22, 2022 Category: Endocrinology Source Type: research
Sporadic medullary thyroid cancer: a systematic review and meta-analysis of clinico-pathological and mutational characteristics predicting recurrence
ConclusionT3 and T4 disease, AJCC stage III and IV disease and the presence of nodal disease are associated with recurrent disease. The heterogeneous reporting of recurrence and the lack of individual patient data precludes larger scale meta-analyses. Future research in this area should involve collaboration to establish standardised definitions of disease recurrence. (Source: Thyroid Research)
Source: Thyroid Research - July 22, 2022 Category: Endocrinology Source Type: research
Virchow node of an unusual aetiology – the experience of a clinical case
ConclusionThis is a rare case in which we incidentally found a follicular nodule in ectopic thyroid tissue in the left supraclavicular fossa. Given the rarity of the situation, clinical sense is the mainstay of treatment and follow-up. (Source: Thyroid Research)
Source: Thyroid Research - May 16, 2022 Category: Endocrinology Source Type: research
Proportion of serum thyroid hormone concentrations within the reference ranges in athyreotic patients on levothyroxine monotherapy: a retrospective study
ConclusionThis study showed that measuring FT3 concentrations rather than FT4 concentrations as the subsequent parameter of thyroid function might be more useful for disease management in terms of the proportion of serum thyroid hormone concentrations within the reference ranges. Furthermore, FT3 measurement could be useful in providing more detailed treatments, including avoiding more aggressive TSH suppressive therapy and identifying the presence of low T3 syndrome in the background. (Source: Thyroid Research)
Source: Thyroid Research - May 10, 2022 Category: Endocrinology Source Type: research
Radioiodine treatment outcome by dosimetric parameters and renal function in hyperthyroidism
ConclusionsMultiple measurements of individual iodine uptake for kinetics estimation may be unnecessary, and a population-based value can be used instead. Patients with renal impairment had similar outcome as other patients, but with a higher risk of dubious uptake measurements. (Source: Thyroid Research)
Source: Thyroid Research - April 25, 2022 Category: Endocrinology Source Type: research
Evaluation of multinodular goiter and primary hyperparathyroidism leads to a diagnosis of AL amyloidosis
ConclusionAmyloid goiter as the primary clinical manifestation secondary to AL amyloidosis with deposition in the thyroid and parathyroid gland is rare. The top differential for amyloid deposits in the thyroid includes systemic amyloidosis or medullary thyroid carcinoma. The definitive diagnosis lies in the histopathology of the thyroid tissue. To diagnose systemic amyloidosis as the etiology for a goiter, a solid understanding of the causes of systemic amyloidosis coupled with a thorough evaluation of the patient ’s history and laboratory data is necessary. (Source: Thyroid Research)
Source: Thyroid Research - April 20, 2022 Category: Endocrinology Source Type: research
Postpartum depression in maternal thyroidal changes
AbstractEvidence in the literature has suggested that there may be an association between thyroid antibodies and depression during pregnancy and in the postpartum period. Thus, this study aims to conduct a systematic review on the prevalence of postpartum depression (PPD) in women with thyroid abnormalities during pregnancy or in the postpartum period. For this review, we used four databases (PubMed, Lilacs, Scielo, and Scopus). Fifteen studies were selected; one study used a case –control design, four used a cross-sectional design and ten utilized prospective cohort designs. All studies were restricted to up to 1 year ...
Source: Thyroid Research - March 29, 2022 Category: Endocrinology Source Type: research
Causes of different goiter rates with the same iodine deficiency among the pastoral and agricultural populations of Tibet: a geographical comparison
ConclusionsThe significantly high intake of the food-borne thyroid hormone by the residents of the pastoral area could be the main reason the residents in the pastoral areas show a lower rate of thyroid goiter than those in the agricultural area. Moreover, the relatively high intake of protein and trace elements, selenium and iron by residents in the pastoral area could be another important factor for reducing the goiter rates. (Source: Thyroid Research)
Source: Thyroid Research - March 19, 2022 Category: Endocrinology Source Type: research
Seasonal variation in calcium treatment after thyroidectomy as surrogate for post-operative hypocalcemia: a retrospective register-based national cohort study
ConclusionIn this cohort, total thyroidectomy performed during August –October was associated with a lower rate of calcium treatment given post-operatively when compared to total thyroidectomy performed during February–April. This would indicate a decreased risk of post-operative hypocalcemia if surgery was carried out after the brighter season. (Source: Thyroid Research)
Source: Thyroid Research - March 19, 2022 Category: Endocrinology Source Type: research
Use of thyroid hormones in hypothyroid and euthyroid patients: a THESIS* survey of Belgian specialists *THESIS: treatment of hypothyroidism in Europe by specialists: an international survey
ConclusionsLT4 tablets is the preferred treatment for hypothyroidism in Belgium. A minority of the respondents would try combined LT4 + LT3 in symptomatic but biochemically euthyroid patients. Thyroid hormones are prescribed for euthyroid infertile women with thyroid autoimmunity and patients with non-toxic goiter, a tendency noted in other European countries, despite current evidence of lack of benefit. (Source: Thyroid Research)
Source: Thyroid Research - March 5, 2022 Category: Endocrinology Source Type: research
Diagnostic characteristics, treatment patterns, and clinical outcomes for patients with advanced/metastatic medullary thyroid cancer
ConclusionsFor the treatment of advanced/metastatic MTC, no specific preference of sequencing systemic agents was observed in the first- and second-line settings. Considering the recent approval of selectiveRET inhibitors for patients withRET-mutant MTC, future research should investigate how treatment patterns evolve for these patients. (Source: Thyroid Research)
Source: Thyroid Research - February 12, 2022 Category: Endocrinology Source Type: research
Synchronous lateral lymph node metastases from papillary and follicular thyroid carcinoma: case report and review of the literature
ConclusionsThis is probably the first case report of a patient with co-existing lateral lymph node PTC and FTC metastases. Consulting previous publications, there is currently a gap of knowledge in terms of how patients with regional FTC metastases should be followed-up and treated, especially when co-occurring with spread high-risk PTC subtypes. Moreover, what guides a seemingly indolent FTC to spread via the lymphatic system remains to be defined from a molecular standpoint. (Source: Thyroid Research)
Source: Thyroid Research - February 4, 2022 Category: Endocrinology Source Type: research
