Comparison of inferior vena cava filter use and outcomes between cancer and non-cancer patients in a tertiary hospital
This study aims to review the rate of adherence to guidelines recommendation and to compare retrieval rates and complications in both cancer and non-cancer patients. (Source: Thrombosis Research)
Source: Thrombosis Research - February 27, 2024 Category: Hematology Authors: N éstor López, Carles Zamora-Martinez, Marc Montoya, Cristina Gabara, María Ortiz, Jesús Aibar Source Type: research
Enoxaparin is safe for the treatment of venous thromboembolisms in patients with renal dysfunction: A retrospective cohort study
Unfractionated heparin (UFH) and low molecular weight heparins (LMWH), such as enoxaparin, are commonly used anticoagulants for the prevention and treatment of venous thromboembolisms. Several studies have compared their safety and efficacy, including a meta-analysis that showed them to be similarly efficacious with no difference in bleeding risk [1]. While UFH has been used in practice longer, LMWH offers a more predictable pharmacokinetic profile and requires less laboratory monitoring. (Source: Thrombosis Research)
Source: Thrombosis Research - February 26, 2024 Category: Hematology Authors: Connor Flynn, Julie Baldassarra, Arzo Hamidi Tags: Letter to the Editors-in-Chief Source Type: research
Bleeding disorders of unknown cause; the role of physiological anticoagulants
A substantial number of patients that are referred to a hematologist for investigation of a bleeding tendency are eventually classified as having bleeding disorder of unknown cause (BDUC). A large BDUC cohort was described by Quiroga et al. in 2007 [1], and then in 2018 Gebhart et al. showed that 73 % of patients in the Vienna Bleeding Biobank, a study setup to systematically evaluate consecutive patients referred to the clinic with bleeding symptoms, have been diagnosed with BDUC [2]. This is in line with other studies indicating that BDUC is diagnosed with increasing frequency over recent years [3,4]. (Source: Thrombosis Research)
Source: Thrombosis Research - February 25, 2024 Category: Hematology Authors: Amaury Monard, Will Thomas, Floor Heubel-Moenen Tags: Editorial Source Type: research
Complications associated to midline- and long peripheral catheters in adults. Systematic review of literature and proposal for a standardized model for data collection
Long peripheral catheters (LPCs) and midline catheters (MCs) are indiscriminately labelled with different names, leading to misclassifications both in primary and secondary studies. The available studies used different methods to report the incidence of catheter-related complications, affecting the possibility of properly comparing the catheter outcomes. The aim of this review was to explore the complications related to LPCs and MCs after reclassifying according to their length. (Source: Thrombosis Research)
Source: Thrombosis Research - February 25, 2024 Category: Hematology Authors: Adam Fabiani, Nicola Aversana, Marilena Santoro, Gianfranco Sanson Tags: Review Article Source Type: research
Statin use and mortality in patients with deep vein thrombosis. Data from the RIETE Registry
The association between statin use and mortality in patients with deep vein thrombosis (DVT) has not been rigorously evaluated. (Source: Thrombosis Research)
Source: Thrombosis Research - February 23, 2024 Category: Hematology Authors: Carmine Siniscalchi, Behnood Bikdeli, David Jim énez, José María Suriñach, Pablo Demelo-Rodríguez, Farès Moustafa, Aída Gil-Díaz, Alberto García-Ortega, Hanh My Bui, Manuel Monreal, RIETE Investigators Tags: Full Length Article Source Type: research
Considerations for instituting pediatric pulmonary embolism response teams: A tool kit
The incidence of pediatric pulmonary embolism (PE) has increased by 200 % in the last decade, but at a single center, it is still infrequent. Given the unique epidemiologic features of pediatric PE, diagnosis is often delayed, and the management is empiric, based on individual physician experience or preference. Thus, there is a strong need for center-specific unifor m management of pediatric PE patients. In adults, the development of pulmonary embolism response teams (PERTs) or PE critical care pathways has shortened the time to diagnosis and the initiation of definitive management. (Source: Thrombosis Research)
Source: Thrombosis Research - February 22, 2024 Category: Hematology Authors: Madhvi Rajpurkar, Rachel P. Rosovsky, Suzan Williams, Anthony K.C. Chan, C. Heleen van Ommen, E. Vincent S. Faustino, Melissa White, Mihir Parikh, Nongnuch Sirachainan, Tina Biss, Neil A. Goldenberg Tags: Full Length Article Source Type: research
Low absolute risk of thrombotic and cardiovascular events in outpatient pregnant women with COVID-19
Pregnancy may contribute to an excess risk of thrombotic or cardiovascular events. COVID-19 increases the risk of these events, although the risk is relatively limited among outpatients. We sought to determine whether outpatient pregnant women with COVID-19 are at a high risk for cardiovascular or thrombotic events. (Source: Thrombosis Research)
Source: Thrombosis Research - February 20, 2024 Category: Hematology Authors: Behnood Bikdeli, Darsiya Krishnathasan, Candrika D. Khairani, Antoine Bejjani, Julia Davies, Nicole Porio, Anthony Tristani, Andre Armero, Ali A. Assi, Victor Nauffal, Umberto Campia, Zaid Almarzooq, Eric Wei, Marcos D. Ortiz-Rios, Valeria Zuluaga-S ánch Tags: Full Length Article Source Type: research
Patterns of atrial fibrillation anticoagulation with rivaroxaban — 7-year follow-up from the Dresden NOAC registry
Data on long-term effectiveness and safety of rivaroxaban for stroke prevention in atrial fibrillation (SPAF) are scarce and not available from randomized clinical trials. (Source: Thrombosis Research)
Source: Thrombosis Research - February 19, 2024 Category: Hematology Authors: Luise Tittl, Sandra Marten, Christiane Naue, Jan Beyer-Westendorf Tags: Full Length Article Source Type: research
Diagnostic strategies in postpartum individuals with suspected venous thromboembolism: A scoping review
The risk of venous thromboembolism (VTE) is increased postpartum and contributes to important morbidity and mortality. While there have been advances in evaluating diagnostic algorithms for suspected VTE during pregnancy, there is limited data for postpartum individuals. (Source: Thrombosis Research)
Source: Thrombosis Research - February 18, 2024 Category: Hematology Authors: Gurjeet Bhangu, Alistair Murray, Areeb Qayyum, Natasha Goumeniouk, Steve Goodacre, Beverley J. Hunt, Omar Touhami, Jodie Tester, Megan Rees, Gary Hammerschlag, Diane Pascoe, Paul E. Ronksley, James A. King, Hyun Choi, Shaunagh McDermott, Gregoire Le Gal, Tags: Full Length Article Source Type: research
DOACs: A perfect fit for patients with bariatric surgery?
Extreme obesity (defined with a body mass index, BMI, of ≥40 kg/m2) is increasing worldwide, so bariatric surgery frequency is increasing to prevent and treat obesity-related health complications. Direct oral anticoagulant (DOACs), without need of laboratory monitoring, are the preferred treatment for venous thromboembolism (VTE) and atrial fibrillation (AF). Bariatric surgery comprises multiple procedures including adjustable gastric banding, sleeve gastrectomy (LSG), Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion with duodenal switch (BPD/DS). (Source: Thrombosis Research)
Source: Thrombosis Research - February 18, 2024 Category: Hematology Authors: Nicolas Gendron, Azita H. Talasaz Tags: Full Length Article Source Type: research
The effects of CYP2C19 genotype polymorphism and clopidogrel resistance on ischemic event occurrence in patients with peripheral arterial disease undergoing revascularization: A prospective cohort study
Peripheral arterial disease (PAD) affects approximately 236 million people worldwide. Therefore, this study aimed to investigate the relationship between CYP2C19 genotype polymorphisms and clopidogrel resistance (CR) following revascularization in patients with PAD. (Source: Thrombosis Research)
Source: Thrombosis Research - February 16, 2024 Category: Hematology Authors: Yongkang Zhang, Qingzhi Ran, Kangli Yin, Yinkai Wang, Jiarui Liu, Yuan Zong, Yuzhen Wang, Yemin Cao Tags: Full Length Article Source Type: research
Multitarget strategy of GATA3 and high-grade serous ovarian carcinoma: Where are we now?
Ovarian cancer, particularly high-grade serous ovarian carcinoma (HGSOC), is one of the leading causes of death among gynecological cancer patients. In this regard, despite excellent cytoreductive surgery and platinum-based therapy, the HGSOC spreads and relapses often, with a poor prognosis. The tumor microenvironment (TME) has recently been found to play an important role in the carcinogenesis of HGSOC; consequently, interactions between the TME and HGSOC may provide a feasible strategy to target HGSOC [1,2]. (Source: Thrombosis Research)
Source: Thrombosis Research - February 16, 2024 Category: Hematology Authors: Mohnad Abdalla, Amr Ahmed El-Arabey, Zhongtao Gai Tags: Letter to the Editors-in-Chief Source Type: research
The ISTH DIC-score predicts early mortality in patients with non-promyelocitic acute myeloid leukemia
This study examined the frequency and prognostic significance, with regards of early mortality, of the presence of overt disseminated intravascular coagulation (DIC) at AML diagnosis and its correlation with clinical and biological characteristics.A retrospective analysis of 351 newly diagnosed non-promyelocytic AML patients was conducted, utilizing the 2018 ISTH DIC-Score criteria to evaluate the presence of overt DIC at AML onset. (Source: Thrombosis Research)
Source: Thrombosis Research - February 15, 2024 Category: Hematology Authors: Giovangiacinto Paterno, Raffaele Palmieri, Cristiano Tesei, Andrea Nunzi, Giorgia Ranucci, Flavia Mallegni, Federico Moretti, Elisa Meddi, Ilaria Tiravanti, Massimiliano Marinoni, Camilla Page, Solaria Fagiolo, Elisa Buzzatti, Roberto Secchi, Carmelo Gurn Tags: Full Length Article Source Type: research
Altered fibrin clot properties are associated with the progression of chronic kidney disease in atrial fibrillation
Formation of denser and resistant to lysis fibrin clot networks has been shown in chronic kidney disease (CKD) and atrial fibrillation (AF). We investigated whether such prothrombotic fibrin clot properties are associated with faster progression of CKD in AF patients. (Source: Thrombosis Research)
Source: Thrombosis Research - February 15, 2024 Category: Hematology Authors: Zbigniew Heleniak, Pawe ł T. Matusik, Anetta Undas Tags: Full Length Article Source Type: research
Standardized direct oral anticoagulants prescription for treatment of acute venous thromboembolism in the emergency department: A quality improvement initiative
This study aimed to evaluate the impact of a standardized prescription for DOACs for VTE on prescription appropriateness. (Source: Thrombosis Research)
Source: Thrombosis Research - February 15, 2024 Category: Hematology Authors: C. Simard, L. Poirier-Blanchette, A. Rizzolo, T. Cafaro, R. Kerzner, H. Mantzanis, M. Koolian, Canadian Venous Thromboembolism Research Network (CanVECTOR) Tags: Letter to the Editors-in-Chief Source Type: research
