Infectious Aneurysms Caused by Streptococcus Pyogenes in Children
We describe the detailed clinical course of rapidly enlarging infective aneurysms during the treatment of endocarditis and purulent pericarditis caused by Streptococcus pyogenes. We show that S. pyogenes aneurysms can enlarge rapidly within 1–2 days. Moreover, we highlight the benefit of transporting patients to a facility offering multidisciplinary treatment, even if vital signs stabilize to the point. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Brief Reports Source Type: research

Chronic Diarrhea Associated with Edwardsiella Tarda Gastroenteritis: A Case Report and Literature Review
Edwardsiella tarda, a Gram-negative bacterium classified into the genus Enterobacteriaceae, causes self-limited gastroenteritis. Here, we report a case of E. tarda gastroenteritis in a previously healthy 12-year-old boy in whom inflammatory bowel disease was precluded by endoscopy and tissue biopsy due to 3-month history of diarrhea, abdominal pain and weight loss. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Brief Reports Source Type: research

Pasteurella multocida as a Rare Cause of Neonatal Meningitis Complicated by Empyema
A neonatal male injured by the family dog developed meningitis secondary to Pasteurella multocida. After initially defervescing with IV antibiotic treatment, he became febrile again, and imaging revealed a skull fracture and fluid collection. Following neurosurgical evacuation and an extended course of antibiotics, the patient was discharged home. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Brief Reports Source Type: research

Liver Enzyme Elevation Related to Human Parainfluenza Virus Type 3 Infection
We present 2 pediatric patients who developed liver enzyme elevation related to human parainfluenza virus type 3 infection. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Brief Reports Source Type: research

Hand Hygiene Compliance Rates in 9 Pediatric Intensive Care Units Across Europe: Results from the Reducing Antimicrobial use and Nosocomial Infections in Kids Network
A unified surveillance mechanism for hand hygiene and hospital-acquired infections for pediatric wards is lacking in Europe. We managed to setup such a mechanism in 9 pediatric intensive care units in 7 European countries, using World Health Organization’s definitions and common methodology which allows for benchmarking among units and countries. Median hand hygiene compliance was found high 82.3% (interquartile range 71.6–94.5%), but gaps in practices were identified. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Brief Reports Source Type: research

Brucellosis: A Rare Cause of Febrile Neutropenia in a Child
We report a case of brucellosis-induced severe neutropenia in a 2-year-old girl who presented with a 2-week history of fever. On clinical examination, the patient was febrile with mild aphthous stomatitis. However, her general condition was stable, and systemic examination did not show involvement of any other organ. Laboratory test results revealed severe neutropenia, mild anemia, and an elevated serum C-reactive protein level. Flow cytometry of peripheral blood leukocytes revealed no malignancy, and blood film morphology was unremarkable except for mild microcytosis and hypochromia. Antineutrophil antibody and Coombs tes...
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Instructive Cases Source Type: research

Streptococcus intermedius Acute Meningitis in an Immunocompetent Child
We report a case of an immunocompetent 6-year-old boy who developed bacterial meningitis due to S. intermedius. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Instructive Cases Source Type: research

COVID-19 in Immunocompromised Children and Adolescents
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: ESPID Reports and Reviews Source Type: research

A Case of Herpes Zoster Due to Varicella-Zoster Virus Vaccines in a 14-Month-old Girl
We report a case of HZ due to VZV vaccines presented in an immunocompetent 14-month-old girl 62 days after vaccination which is the youngest case from the first dose of the VZV vaccine in immunocompetent children. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Vaccine Reports Source Type: research

Adherence to Recommendations for Βacillus Calmette-Guérin Vaccination of High-risk Neonates in Greece
In 2016 a Βacillus Calmette-Guérin vaccination policy targeting high-risk neonates for tuberculosis before discharge from maternity hospital was adopted in Greece. Vaccination rates were 38.2% in 2019 and 24.7% in 2020. Vaccination coverage varied by risk group (higher for neonates in close contact with an active noncompliant or multidrug-resistant tuberculosis case and lower for Roma and immigrant neonates). (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Vaccine Reports Source Type: research

Current Aspects of Pediatric Pharmacokinetics and Pharmacodynamics of Antimicrobials in Japan: Importance of the Promotion of Population PK/PD Analysis
Pharmacologic knowledge is important for pediatricians conducting feasible pharmacokinetic or pharmacodynamic (PK/PD) studies or applying effective antimicrobial therapies in children. Because of the difficulties in conducting PK/PD studies in children, antimicrobial PK/PD data in children are still limited. To fill in the lack of knowledge, promotion of population PK/PD analysis, which allows us to handle sparse sampling data from individual patients, is important because it is considered a suitable methodology to conduct PK/PD studies in children with limited blood drug concentration data for PK/PD analysis. Population P...
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Review Articles Source Type: research

Pseudomonas aeruginosa Early-Onset Neonatal Sepsis: Could Maternal Healthcare Occupation Be a Risk Factor?
Pseudomonas aeruginosa is a rare cause of early-onset sepsis in neonates, even among infants with identifiable risk factors. Herein we describe the first case, to our knowledge, of P. aeruginosa early-onset sepsis in a term infant with no identifiable risk factor and propose that maternal healthcare occupation could predispose to gastrointestinal/genital colonization with this potential pathogen. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Maternal-Neonatal Reports Source Type: research

Comprehensiveness of Testing Among Herpes Simplex Virus Infected Infants: A Multicenter Cohort Study
Despite clear testing recommendations for herpes simplex virus (HSV) infection in infants, few data exist on the comprehensiveness of HSV testing in practice. In a 23-center study of 112 infants with confirmed HSV disease, less than one-fifth had all recommended testing performed, highlighting the need for increased awareness of and adherence to testing recommendations for this vulnerable population. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Maternal-Neonatal Reports Source Type: research

Infections With Stenotrophomonas maltophilia in Children Undergoing Anticancer Therapy or Hematopoietic Cell Transplantation: A Multicenter Nationwide Study
Conclusions: The risk of SM infections and the occurrence of resistant bacterial strains in allo-HCT patients were comparable to PHO patients. Irrespective of target antibiotic therapy, the outcome of SM infections was better in the PHO setting. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Immunology and Host Response Source Type: research

Comparison of Persistent Symptoms Following SARS-CoV-2 Infection by Antibody Status in Nonhospitalized Children and Adolescents
Conclusions: These findings highlight the existence of nonhospitalized youth who may also experience persistent COVID symptoms. Children and adolescents are less likely to experience persistent COVID symptoms than adults and more likely to be symptomatic, experience severe symptoms and have unhealthy weight compared with children/adolescents without persistent COVID symptoms. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: COVID Reports Source Type: research