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The Impact of Childhood and Parental Vaccination on SARS-CoV-2 Infection Rates in Children
Background: The data on the indirect protection of children via the coronavirus disease 2019 (COVID-19) vaccination of household members are insufficient, and analyses to evaluate the efficacy of COVID-19 vaccines are limited. Methods: We gathered data on 12,442 patients under the age of 18 regarding the vaccination status of their household members, their vaccine preferences and doses, and their previous history of COVID-19 infection immediately before the patients were administered a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) test for severe acute respiratory syndrome coronavirus 2 (SAR...
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: COVID Reports Source Type: research

SARS-CoV-2 Infections in Icelandic Children: Close Follow-up of All Confirmed Cases in a Nationwide Study
This study helps shed light on true complication rates of children with confirmed SARS-CoV-2 infection. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: COVID Reports Source Type: research

Minimal Cross-resistance to Tenofovir in Children and Adolescents Failing ART Makes Them Eligible for Tenofovir-Lamivudine-Dolutegravir Treatment
Background: Fixed-dose combination of dolutegravir (DTG) with tenofovir disoproxil fumarate (TDF) and lamivudine (3TC) likely improves adherence and has a favorable resistance profile. We evaluated predicted efficacy of TLD (TDF-3TC-DTG) in children and adolescents failing abacavir (ABC), zidovudine (AZT), or TDF containing regimens. Methods: Drug resistance mutations were analyzed in a retrospective dataset of individuals (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: HIV Reports Source Type: research

Cluster of Parechovirus Central Nervous System Infections in Young Infants—Tennessee, 2022
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Current Abstracts Source Type: research

SARS-CoV-2 Infection in Children and Adolescents Living With HIV in Madrid
Multicenter study designed to describe epidemiologic and clinical characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive cases registered among children and adolescents living with HIV (CALWH). SARS-CoV-2 infection was confirmed in 13.3% of CALWH, with all patients presenting mild symptoms, and the outcome was good in all patients. None of the HIV- and antiretroviral treatment-related variables studied were associated with greater infection risk or could be considered protective. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: HIV Reports Source Type: research

Incidence, Characteristics, and Outcomes of Clinically Undetected Bacteremia in Children Discharged Home From the Emergency Department
Conclusion: The rate of undetected true bacteremia in our study was low and our data suggest that significant clinical deterioration during the first 24 hours is rare. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Original Studies Source Type: research

Clinical Features, Antimicrobial Resistance, and Serogroups of Nontyphoidal Salmonella Isolated From Infants Less Than 3 Months Old in the Recent Decade
Conclusions: The serogroups varied with time, and the main causes of iNTS, groups C2 and E, increased over the past decade. The prevalence of AMR also increased, especially for iNTS. Given the low iNTS rate and high AMR, routine antibiotic use among infants with NTS infections between 1 and 3 months old should be reconsidered. Further large-scale research is required to formulate therapeutic strategies. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Original Studies Source Type: research

Etiology and Risk Factors for Admission to the Pediatric Intensive Care Unit in Children With Encephalitis in a Developing Country
Objective: To describe a cohort of pediatric patients with encephalitis and their risk factors for admission to the pediatric intensive care unit (PICU). Study Design: Children ( (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Original Studies Source Type: research

Clinical and Socioeconomic Burden of Respiratory Syncytial Virus in Iceland
Introduction: Respiratory syncytial virus (RSV), a very common pathogen, causes variable disease severity. In addition to considerable clinical burden on children, their families and healthcare facilities, RSV infections in children also carry significant direct and indirect socioeconomic burden. Methods: We analyzed data from 5 consecutive RSV seasons (2015–2020) and used virologically confirmed RSV infections and age (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Original Studies Source Type: research

Prolonged Breastfeeding and the Risk of Plasmodium vivax Infection and Clinical Malaria in Early Childhood: A Birth Cohort Study
Conclusion: P. vivax infections in early childhood are underreported in the Amazon, are associated with anemia at 2 years of age, and appear to be partially prevented by prolonged breastfeeding. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Original Studies Source Type: research

Meta-analysis of the Risk Factors for Urinary Tract Infection in Children
Conclusions: Being overweight or obese and having poor fluid intake are modifiable risk factors that increase the risk for UTIs in children. Breast-feeding and circumcision are associated with a decreased occurrence of UTIs. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2022 Category: Infectious Diseases Tags: Original Studies Source Type: research

The Loss of Respiratory Syncytial Virus Seasonality and the Effects on Palivizumab Administration
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - August 16, 2022 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Acute Generalized Exanthematous Pustulosis Associated With a COVID-19 Infection
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - August 16, 2022 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

COVID-19 Disease in Children with Medical Complexity in a Pediatric Long-term Care Facility: A Case Series
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - August 16, 2022 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Did Hospitalization Age Decrease in Children in the Omicron (B.1.1.529) Era?
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - August 16, 2022 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research