Review of Evidence for Environmental Causes of Uveal Coloboma
Uveal coloboma is a condition defined by missing ocular tissues and is a significant cause of childhood blindness. It occurs from a failure of the optic fissure to close during embryonic development,and may lead to missing parts of the iris, ciliary body, retina, choroid, and optic nerve. Because there is no treatment for coloboma, efforts have focused on prevention. While several genetic causes of coloboma have been identified, little definitive research exists regarding the environmental causes of this condition. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 30, 2021 Category: Opthalmology Authors: Evan B. Selzer, Delphine Blain, Robert B. Hufnagel, Philip J. Lupo, Laura E. Mitchell, Brian P. Brooks Tags: Review article Source Type: research
Clinical characteristics and treatment outcomes of Cytomegalovirus anterior uveitis and endotheliitis: a systematic review and meta-analysis
Cytomegalovirus (CMV) anterior uveitis is the most common form of ocular manifestation of CMV in immunocompetent individuals. The difficulty in diagnosing CMV anterior uveitis may delay adequate treatment and affect outcomes. We sought to review systemically the overall clinical characteristics and compare treatment outcomes in CMV anterior uveitis and endotheliitis. A literature search was performed, and studies describing clinical characteristics, treatment regimens, and outcomes that included more than five treated eyes were included. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 23, 2021 Category: Opthalmology Authors: Rina La Distia Nora, Ikhwanuliman Putera, Yuri Dwi Mayasari, Wandya Hikmahwati, Adinda Mulya Pertiwi, Asri Salima Ridwan, Ratna Sitompul, Mark Westcott, Soon-Phaik Chee, Carlos Pavesio, Zheng Xian Thng, Vishali Gupta, Rupesh Agrawal Tags: Review article Source Type: research
Eye disease in kidney transplantation: clinical challenges in a unique patient population
Eye disease is common among kidney transplant recipients and their management is challenging. Chronic kidney disease is associated with ocular complications, both independently and in the context of various systemic disorders. In addition, chronic immunosuppression predisposes kidney transplant recipients to an array of long-term ocular issues. This may be broadly categorized into infections, malignancies, and other immunosuppression-specific side effects. The interdependence of kidney disease, transplant pharmacotherapy and ocular health therefore requires a multispecialty approach. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 22, 2021 Category: Opthalmology Authors: EISHA K. MULTANI, DALVIR BAJWA, PRIYANIKA K. MULTANI, EHSAN NOBAKHT, DOMINIC RAJ, ROHAN S. PAUL, ROHAN S. PAUL Tags: Reviews in medicine Source Type: research
Table of Contents
(Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 15, 2021 Category: Opthalmology Source Type: research
Comment on: “Meta-analysis of ocular axial length in newborns and infants up to 3 years of age”
I read with interest the recent study by Groot and coworkers entitled ” Meta-analysis of ocular axial length in newborns and infants up to 3 years of age”3.In this paper the authors merged the axial length data in 0-3 year old infants in the literature, and a growth curve was illustrated based on the summarized data. Although the idea was novel and the results wer e very practical; however, it needs some comments. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 11, 2021 Category: Opthalmology Authors: Ali Aghajani, Samira Chaibakhsh Source Type: research
Efficacy and safety of intravitreal and periocular injection of corticosteroids in noninfectious uveitis: a systematic review
Uveitis is among the leading causes of visual loss in the working age population. In noninfectious uveitis, corticosteroids are the first line therapy. We sought to review systematically the evidence regarding the regional corticosteroid delivery modalities in the treatment of noninfectious uveitis. A 5-database search (Pubmed, ISI Web of Science, Cochrane, ClinicalTrials.gov, and Scopus) was performed from inception to February, 2021. Nineteen studies with a total of 1,935 eyes of 1,753 patients were selected from 8,922 abstracts retrieved by the initial search. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 8, 2021 Category: Opthalmology Authors: Rafael Jos é-Vieira, André Ferreira, Pedro Menéres, Bernardo Sousa-Pinto, Luís Figueira Tags: Review article Source Type: research
Efficacy and safety of intravitreal and periocular injection of corticosteroids in non-infectious uveitis: a systematic review
Uveitis is among the leading causes of visual loss in the working age population. In non-infectious uveitis, corticosteroids are the first line therapy. We sought to review systematically the evidence regarding the regional corticosteroid delivery modalities in the treatment of non-infectious uveitis. A five-database search (Pubmed, ISI Web of Science, Cochrane, ClinicalTrials.gov, and Scopus) was performed from inception to February, 2021. Nineteen studies with a total of 1935 eyes of 1753 patients were selected from 8922 abstracts retrieved by the initial search. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 8, 2021 Category: Opthalmology Authors: Rafael Jos é-Vieira, André Ferreira, Pedro Menéres, Bernardo Sousa-Pinto, Luís Figueira Tags: Review article Source Type: research
Pars Plana Vitrectomy versus Scleral Buckle: A Comprehensive Meta-Analysis of 15,947 Eyes
Rhegmatogenous retinal detachment (RRD) is an emergent vision-threatening condition that occurs in 1 in 10,000 people each year.14,31 In RRDs, an ingress of subretinal fluid extending from a retinal break leads to an elevation and detachment of the neurosensory retina from the retinal pigment epithelium. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 8, 2021 Category: Opthalmology Authors: Arjan S. Dhoot, Marko M. Popovic, Prem A.H. Nichani, Arshia Eshtiaghi, Andrew Mihalache, Aman P. Sayal, Hannah Yu, Charles C. Wykoff, Peter J. Kertes, Rajeev H. Muni Tags: Review article Source Type: research
Diagnosis and Management of Degenerative Retinoschisis and Related Complications
Degenerative retinoschisis is a common condition characterized by elevation of the inner layers of the peripheral retina. While uncomplicated retinoschisis (i.e. with no associated retinal layer breaks) is almost invariably a benign process, retinal detachment associated with isolated outer layer breaks (termed schisis-detachment) is fairly common. Historically, schisis-detachment has been treated with a variety of interventions ranging from retinopexy to intraocular surgery. Based on published descriptions of the natural history of the disease, these interventions are likely unnecessary in many cases and may place the pat...
Source: Survey of Ophthalmology - December 8, 2021 Category: Opthalmology Authors: Steven Ness, Manju L. Subramanian, Xuejing Chen, Nicole H. Siegel Tags: Review article Source Type: research
Nutritional supplementation in the prevention and treatment of Glaucoma
Glaucoma is a chronic optic neuropathy that creates a significant burden on public health. Oxidative stress is hypothesised to play a role to glaucoma progression, and its reduction is being analysed as a therapeutic target. Dietary antioxidants play a crucial role in helping provide insight into this hypothesis. We reviewed 71 trials, interventional, I -vivo and I -vitro, including 11 randomised controlled trials, to determine if adjunctive nutritional supplementation could lead to a reduction in oxidative stress and prevent glaucomatous progression. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 7, 2021 Category: Opthalmology Authors: Sarah Chaudhry, Hamish Dunn, Nicole Carnt, Andrew White Tags: Review article Source Type: research
A Review of Potential Novel Glaucoma Therapeutic Options Independent of Intraocular Pressure
Glaucoma, a progressive optic neuropathy characterized by retinal ganglion cell degeneration and visual field loss, is the leading cause of irreversible blindness worldwide. Intraocular pressure (IOP) is presently the only modifiable risk factor demonstrated to slow or halt disease progression; however, glaucomatous damage persists in almost 50% of patients despite significant IOP reduction. Many studies have investigated the non-IOP-related risk factors that contrib ute to glaucoma progression as well as interventions that can prevent or delay glaucomatous neurodegeneration and preserve vision throughout life, independ...
Source: Survey of Ophthalmology - December 7, 2021 Category: Opthalmology Authors: Wesam Shamseldin Shalaby, Osama M. Ahmed, Michael Waisbourd, L. Jay Katz Tags: Review article Source Type: research
Author's reply to: Comment on: “Meta-analysis of ocular axial length in newborns and infants until three years of age”
We thank our colleagues Aghajani and Chaibakhsh for thoroughly reading our paper and taking the time to comment on the results. We would like to reply to their statements with the following. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - December 3, 2021 Category: Opthalmology Authors: Annabel L.W. Groot, Birgit I. Lissenberg-Witte, Laurentius J. van Rijn, Dyonne T. Hartong Tags: Letter Source Type: research
Gut microbiota and age-related macular degeneration: A growing partnership
Age-related macular degeneration (AMD) is a leading cause of severe, irreversible vision impairment in developed countries, and its prevalence is rising all over the world, increasing sharply with age. AMD represents an acquired degeneration of the retina that causes significant central visual impairment through a combination of non-neovascular and neovascular derangement. The main risk factors for the development of advanced AMD are increasing age, genetic factors, and cigarette smoking; however, the exact pathophysiology of AMD is yet relatively poorly understood. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - November 26, 2021 Category: Opthalmology Authors: M ário Lima-Fontes, Luís Meira, Pedro Barata, Manuel Falcão, Ângela Carneiro Source Type: research
Sensitivity and Specificity of Handheld Fundus Cameras for Eye Disease: A Systematic Review and Pooled Analysis
In order to evaluate the accuracy of commercially available handheld fundus cameras for a variety of ophthalmic diagnoses, we conducted a systematic review, searching PubMed and PubMed Central and performing a bivariate analysis to determine the pooled sensitivity and specificity of handheld fundus cameras. Eleven studies validating handheld fundus cameras against a gold-standard method for disease diagnosis were included. For non-mydriatic images, pooled sensitivity was 83% (95% CI: 77-88%) and specificity was 92% (95% CI: 79-97%). (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - November 22, 2021 Category: Opthalmology Authors: Brittney J. Palermo, Samantha L. D'Amico, Brian Y. Kim, Christopher J. Brady Source Type: research
Oculomotor nerve schwannoma: case series and literature review
Oculomotor nerve schwannomas (ONS) are rare benign cranial nerve tumors. There are only a limited number of reports on this pathology in the literature, and there is currently no established management guidelines that aid providers in deciding on surgical versus non-surgical management. We assess the published literature on the topic to identify indications for treatment as well as outcome measures (e.g., local control rates, survival rates, and complication rates) that have been reported as associated with the various treatment modalities. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - November 20, 2021 Category: Opthalmology Authors: Vivian Paraskevi Douglas, Christopher Flores, Konstantinos AA Douglas, Mitchell B. Strominger, Ekkehard Kasper, Nurhan Torun Tags: Review article Source Type: research
