Occam versus hickam
A 23-year-old man presented with new onset horizontal diplopia 5 months after a left orbital floor fracture. Examination revealed bilateral abduction deficits and disc swelling. Urgent MRI and MRI showed no significant abnormalities in the CNS. Lumbar puncture revealed a minimally elevated opening pressure and significant leukocytosis. Additional CSF testing revealed probable Lyme meningitis. The patient responded to a course of oral doxycycline, with rapid resolution of his diplopia, abduction deficits, and disc edema. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - June 16, 2022 Category: Opthalmology Authors: Lucy Cobbs, Ann P. Murchison, Adam DeBusk, Jurij R. Bilyk Tags: Clinical challenges Source Type: research
Occam vs Hickam
A 23-year-old man presented with new onset horizontal diplopia 5 months after a left orbital floor fracture. Examination revealed bilateral abduction deficits and disc swelling. Urgent MRI and MRI showed no significant abnormalities in the CNS. Lumbar puncture revealed a minimally elevated opening pressure and significant leukocytosis. Additional CSF testing revealed probable Lyme meningitis. The patient responded to a course of oral doxycycline, with rapid resolution of his diplopia, abduction deficits, and disc edema. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - June 16, 2022 Category: Opthalmology Authors: Lucy Cobbs, Ann P. Murchison, Adam DeBusk, Jurij R. Bilyk Tags: Clinical challenges Source Type: research
Table of Contents
(Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - June 9, 2022 Category: Opthalmology Source Type: research
The safety of intracameral phenylephrine – A systematic review
Intracameral phenylephrine is commonly used in ophthalmic surgery as an alternative or supplement to mydriatic eye drops; hence, the importance of an evidence-based understanding of its risk-benefit profile is vital. We performed a comprehensive search in the PubMed, Google Scholar and Cochrane databases for published studies and case reports relating to the use of intracameral phenylephrine. Articles from 1958 to 2021 with the following keywords were used: “intracameral phenylephrine”, “intracameral mydriatics”, “phenylephrine”, “pupil dilation”, “complications”. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - June 9, 2022 Category: Opthalmology Authors: Akash Gowda, Wilson Wong Jun Jie, Robert Casson, Weng Onn Chan Tags: Review article Source Type: research
Laser Treatment for Choroidal Melanoma: Current Concepts
Laser treatment has offered a relatively nonsurgical alternative for eye, life, and vision-sparing treatment of malignant melanoma of the choroid. Historically, the most commonly used forms of lasers were xenon-arc, argon laser, krypton laser, and the more recent transpupillary thermotherapy (TTT) and photodynamic therapy (PDT). Melanomas selected for laser treatment tend to be smaller and visibly accessible, which means these tumors are usually located in the posterior choroid. Laser treatments have been associated with both local tumor destruction and side effects. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - May 26, 2022 Category: Opthalmology Authors: Abhilasha Maheshwari, Paul T. Finger Source Type: research
An eye for an eye, a tooth for a tooth
A 77-year-old man presented with the complaint of a painless decrease in vision in both eyes for one year. He underwent bilateral cataract surgery without improvement. Neuroimaging and genetic testing for mitochondrial disease was negative. Examination was consistent with a diagnosis of toxic-nutritional optic neuropathy. On further questioning the patient admitted chronic ingestion of mouthwash 3 times daily in the past 18 months after completion of dental work. After discontinuation of mouthwash ingestion, visual acuity and fields improved. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - May 18, 2022 Category: Opthalmology Authors: Francesco Pellegrini, Rod Foroozan Tags: Clinical challenges Source Type: research
Table of Contents
(Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - May 1, 2022 Category: Opthalmology Source Type: research
Correspondence regarding: Review Article: Ocular Syphilis
We read with great interest the review article on ocular syphilis published in your journal. 1 Furtado and Smith should be congratulated for the excellent article which has addressed the re-emergence of syphilis and highlighted the varied presentations of ocular syphilis. The article mentions vitritis associated with retinitis and chorioretinitis. We would like to point out that intermediate uveitis, in itself, is an important manifestation of ocular syphilis, specifically in immunocompetent individuals. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - May 1, 2022 Category: Opthalmology Authors: Harpreet Kaur Narde, Rohan Chawla Source Type: research
Authors' response
We thank Narde and Chawla3 for their interest in our review on ocular syphilis and for sharing their clinical experience with the condition, including illustration with some excellent fundus images. They highlight a point made in our review2 that isolated vitritis may be a presentation of this reemerging infectious eye disease. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - April 30, 2022 Category: Opthalmology Authors: Jo ão M. Furtado, Justine R. Smith Tags: Letter Source Type: research
Author's Response
We thank Narde and Chawla3 for their interest in our review on ocular syphilis, and for sharing their clinical experience with the condition, including illustration with some excellent fundus images. They highlight a point made in our review2 that isolated vitritis may be a presentation of this re-emerging infectious eye disease. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - April 30, 2022 Category: Opthalmology Authors: Jo ão M. Furtado, Justine R. Smith Source Type: research
Treat-and-Extend Versus Alternate Dosing Strategies with Anti-Vascular Endothelial Growth Factor agents to treat Center Involving Diabetic Macular Edema: A Systematic Review and Meta-analysis of 2346 Eyes
Anti-vascular endothelial growth factor (Anti-VEGF) agents are the standard of care for diabetic macular edema (CI-DME) with vision loss. They are commonly administered using several treatment protocols, including fixed, pro re nata (PRN) and treat-and-extend (T&E) regimens. Because of the lack of evidence defining an ideal treatment paradigm, we systematically compared T&E with fixed or PRN regimens. Visual acuity improvement was similar when comparing T&E to fixed or PRN dosing at 12 and 24 months. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - April 23, 2022 Category: Opthalmology Authors: Gurkaran S. Sarohia, Keean Nanji, Mohammad Khan, Muhammad F. Khalid, Daniel Rosenberg, Deven M. Deonarain, Mark R. Phillips, Lehana Thabane, Peter Kaiser, Sunir Garg, Sobha Sivaprasad, Charles C. Wykoff, Varun Chaudhary Tags: REVI Source Type: research
Neuro-ophthalmic imaging and visual assessment technology for spaceflight -associated neuro-ocular syndrome (SANS)
Spaceflight associated neuro-ocular syndrome (SANS) refers to a unique collection of neuro-ophthalmic clinical and imaging findings observed in astronauts after long-duration spaceflight. Current in-flight and postflight imaging modalities (e.g., optical coherence tomography, orbital ultrasound, and funduscopy) have played an instrumental role in the understanding and monitoring of SANS development; however, the precise etiology for this neuro-ophthalmic phenomenon is still not completely understood. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - April 21, 2022 Category: Opthalmology Authors: Joshua Ong, Alireza Tavakkoli, Gary Strangman, Nasif Zaman, Sharif Amit Kamran, Quan Zhang, Vladimir Ivkovic, Andrew G. Lee Tags: Review article Source Type: research
Neuro-ophthalmic Imaging and Visual Assessment Technology for Spaceflight Associated Neuro-ocular Syndrome (SANS)
Spaceflight associated neuro-ocular syndrome (SANS) refers to a unique collection of neuro-ophthalmic clinical and imaging findings observed in astronauts after long duration spaceflight. Current in-flight and post-flight imaging modalities (e.g., optical coherence tomography, orbital ultrasound, and funduscopy) have played an instrumental role in the understanding and monitoring of SANS development; however, the precise etiology for this neuro-ophthalmic phenomenon is still not completely understood. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - April 21, 2022 Category: Opthalmology Authors: Joshua Ong, Alireza Tavakkoli, Gary Strangman, Nasif Zaman, Sharif Amit Kamran, Quan Zhang, Vladimir Ivkovic, Andrew G. Lee Tags: Review article Source Type: research
Switching between anti-VEGF agents in the management of refractory diabetic macular edema: A systematic review
Refractory diabetic macular edema (DME) to monthly intravitreal anti-vascular endothelial growth factor (VEGF) monotherapy has a prevalence of approximately 40% in landmark clinical trials. Options for these patients include use of intravitreal steroids, focal laser, or switching to an alternative anti-VEGF agent. We summarize the key conclusions from studies analyzing the efficacy of switching anti-VEGF agents for refractory DME. Twenty-four studies were included in analysis. The most common definitions of refractory in the included studies were a central retinal thickness (CRT) greater than 300 μm or a reduction in CRT ...
Source: Survey of Ophthalmology - April 19, 2022 Category: Opthalmology Authors: Kian Madjedi, Austin Pereira, Brian G. Ballios, Parnian Arjmand, Peter J. Kertes, Michael Brent, Peng Yan Source Type: research
The prevalence of retinopathy in prediabetes: A systematic review
Prediabetes is defined as suboptimal glycemia that does not reach the threshold for type 2 diabetes 1,4. Worldwide, approximately one in 13 adults (374 million) aged 20-79 years have prediabetes, and the vast majority are unaware of the diagnosis 23. There is a significant predicted burden, with the International Diabetes Federation projecting 587 million people (8.3% of adults) to have prediabetes by 2045 23. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - April 14, 2022 Category: Opthalmology Authors: Varo Kirthi, Paul Nderitu, Uazman Alam, Jennifer R. Evans, Sarah Nevitt, Rayaz A. Malik, David Hopkins, Timothy L. Jackson Tags: Review article Source Type: research
