Table of Contents
(Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - September 22, 2023 Category: Opthalmology Source Type: research

Barriers to care in neovascular age-related macular degeneration: Current understanding, developments, and future directions
Neovascular age-related macular degeneration (nAMD) is the advanced and irreversible stage of AMD, the leading cause of severe vision loss in older adults. While anti-vascular endothelial growth factor (anti-VEGF) injections have been shown to preserve or improve vision quality in eyes with nAMD, the treatment regimen can be demanding of patients and caregivers, leading to lower rates of adherence. Therefore, it is crucial that disparities and obstacles in nAMD care are identified to improve access to treatment. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - September 15, 2023 Category: Opthalmology Authors: Alison Choi, Baraa S. Nawash, Katherine Du, Joshua Ong, Jay Chhablani Tags: Review article Source Type: research

Histological changes in retinal detachment: A systematic review for the clinician
Although there have been numerous innovations in the management of retinal detachment (RD) over the past decades, there is still limited understanding of the pathophysiological processes that take place before and after repair. Summarizing key concepts using animal studies may allow a better assessment of common pre and postoperatively microstructural abnormalities in RD. We performed a systematic literature review on Ovid MEDLINE, EMBASE, and Cochrane Controlled Register of Trials from January, 1968, to January, 2022, searching animal or human studies reporting retinal histologic changes following primary or induced RD. (...
Source: Survey of Ophthalmology - August 29, 2023 Category: Opthalmology Authors: Isabela Martins Melo, Tianwei Ellen Zhou, Flavia Nagel, Nikhil S. Patil, Fathima Afira Faleel, Marko Popovic, Rajeev H. Muni Source Type: research

Cataract surgery following refractive surgery: Principles to achieve optical success and patient satisfaction
A growing number of patients with prior refractive surgery are now presenting for cataract surgery. Surgeons face a number of unique challenges in a patient population that tends to be highly motivated to retain or regain functional uncorrected acuity postoperatively. Primary challenges include recognition of the specific type of prior surgery, use of appropriate intraocular lens (IOL) power calculation formulas, matching IOL style with spherical aberration profile, the recognition of corneal imaging patterns that are and are not compatible with toric and/or presbyopia-correcting lens implantation, and surgical technique m...
Source: Survey of Ophthalmology - August 26, 2023 Category: Opthalmology Authors: Tanner J. Ferguson, J. Bradley Randleman Tags: Review article Source Type: research

Table of Contents
(Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - August 12, 2023 Category: Opthalmology Source Type: research

Macular neovascularization in inherited retinal diseases: A review
Inherited retinal diseases (IRDs) are the most common cause of blindness in working-age adults. Macular neovascularization (MNV) may be a presenting feature or occurs as a late-stage complication in several IRDs. We performed an extensive literature review on MNV associated with IRDs. MNV is a well-known complication of Sorsby fundus dystrophy and pseudoxanthoma elasticum. Those with late-onset Stargardt disease may masquerade as exudative age-related macular degeneration (AMD) when MNV is the presenting feature. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - August 4, 2023 Category: Opthalmology Authors: Rachael C. Heath Jeffery, Fred K. Chen Tags: Review article Source Type: research

Detection of subclinical microvascular changes in systemic lupus erythematous using optical coherence tomography angiography: A systematic review and meta-analysis
Systemic lupus erythematosus (SLE) is a chronic, systemic, autoimmune connective tissue disease that affects several vascular territories. This systematic review sought to assess the role of optical coherence tomography angiography (OCTA) in detecting subclinical microvascular alterations in SLE patients.PubMed, Scopus, and Web of Science databases were systematically searched until January 21st, 2023. Studies using OCTA as a primary diagnostic method to evaluate the macular microvasculature of SLE patients versus healthy controls were included. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - August 4, 2023 Category: Opthalmology Authors: Andr é Ferreira, Rafael José Vieira, Maria João Furtado, Miguel Lume, José P. Andrade, Pedro Menéres Tags: Review article Source Type: research

Macular neovascularisation in inherited retinal diseases: A review
Inherited retinal diseases (IRDs) are the most common cause of blindness in working-age adults. Macular neovascularisation (MNV) may be a presenting feature or occur as a late-stage complication in several IRDs. We performed an extensive literature review on MNV associated with IRDs. MNV is a well-known complication of Sorsby fundus dystrophy and pseudoxanthoma elasticum. Those with late-onset Stargardt disease may masquerade as exudative age-related macular degeneration (AMD) when MNV is the presenting feature. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - August 4, 2023 Category: Opthalmology Authors: Rachael C. Heath Jeffery, Fred K. Chen Tags: Review article Source Type: research

Pathogenesis of myopic choroidal neovascularization: A systematic review and meta-analysis
Myopic choroidal neovascularization (CNV) is a vision-threatening complication of high myopia. Here we systematically review cohort, case-control, and cross-sectional studies in PubMed, Embase, and Web of Science; and summarize the associated factors of myopic CNV using meta-analysis where applicable. Among 1,333 records assessed, 50 were found eligible, all having a low to moderate risk of bias. Highly myopic eyes with CNV had a higher risk of lacquer cracks (OR=2.88) and of patchy chorioretinal atrophy (OR=3.43) than those without. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - July 28, 2023 Category: Opthalmology Authors: Xiu Juan ZHANG, Xiu Nian CHEN, Fang Yao TANG, Simon SZETO, Xiang Tian LING, Zi Xuan LIN, Clement C. THAM, Chi Pui PANG, Li Jia CHEN, Jason C. YAM Tags: Review article Source Type: research

New developments in the management of persistent corneal epithelial defects
Letter to the editor: (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - July 25, 2023 Category: Opthalmology Authors: Mar ía García-Lorente, Marina Rodríguez-Calvo-de-Mora, José-María Sánchez-González, Davide Borroni, Francisco Zamorano-Martín, Carlos Rocha-de-Lossada Tags: Letter Source Type: research

New developments in the management of persistent corneal epithelial defects.
Letter to the editor: (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - July 25, 2023 Category: Opthalmology Authors: Mar ía García-Lorente, Marina Rodríguez-Calvo-de-Mora, José-María Sánchez-González, Davide Borroni, Francisco Zamorano-Martín, Carlos Rocha-de-Lossada Source Type: research

Tamoxifen retinopathy: A comprehensive review
Tamoxifen is a selective estrogen receptor modulator used mainly for the treatment of breast cancer. Based on the case reports and studies performed to date on the retinal toxicity of tamoxifen, retinopathy appears to occur in as many as 12% of patients taking 20 mg tamoxifen a day for over 2 years. Of this 12%, as many as half develop symptomatic changes in visual acuity. Retinal changes consist primarily of crystalline deposits, cystoid macular edema, hyperreflective deposits in the inner retinal layers, and telangiectasia. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - July 21, 2023 Category: Opthalmology Authors: Stephen Tenney, Aruoriwo Oboh-Weilke, David Wagner, Mike Yuan Chen Source Type: research

Retromode imaging in retinal diseases: A systematic review of the literature
Retromode scanning laser ophthalmoscope imaging (RM-SLO) captures a pseudo-3-dimensional image of the ocular fundus. RM-SLO was introduced first in the year 2008 using the Nidek F-10 scanning laser ophthalmoscope (F-10; Nidek, Gamagori, Japan). At that time, no major role was described for this imaging modality. The interest in RM-SLO is reemerging with the recent advent of the Mirante that combines SLO and optical coherence tomography (Nidek Co., Gamagori, Japan) that can capture retromode images of the fundus. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - July 20, 2023 Category: Opthalmology Authors: Georges Sukkarieh, Mohamad Issa, Sebastien Bruneau, Aude Couturier, Ramin Tadayoni Tags: Review article Source Type: research

Secondhand smoke exposure and ocular health: A systematic review
The toxicology of secondhand smoke (SHS), along with the harm of its exposure on human health, has been generally acknowledged; however, specific evidence is lacking on the association between SHS exposure and ocular health. In this systematic review (PROSPERO registration number: CRD42022247992), we included 55 original articles published by 12 May 2023 that dealt with SHS exposure and ocular disorders such as eye irritation, conjunctivitis, dry eye diseases, uveitis, myopia, astigmatism, contact lens discomfort, age-related macular degeneration, glaucoma, thyroid eye disease; that addressed the ocular neurovascular struc...
Source: Survey of Ophthalmology - July 19, 2023 Category: Opthalmology Authors: Youjuan Zhang, Xiu Juan Zhang, Nan Yuan, Yu Meng Wang, Patrick Ip, Li Jia Chen, Clement C. Tham, Chi Pui Pang, Jason C. Yam Source Type: research

GLP-1 Receptor Agonists and Diabetic Retinopathy: A Meta-Analysis of Randomized Clinical Trials
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are used to treat type 2 diabetes mellitus. Recent research suggests GLP-1 RAs may influence diabetic retinopathy (DR). We searched ClinicalTrials.gov for trials comparing FDA-approved GLP-1 RAs to placebo, insulin, or oral antidiabetic medicine. Rates of DR, ocular adverse events (AEs), demographics, and clinical characteristics were compared amongst cohorts on 93 trials.GLP-1 RA use was significantly associated with increased risk of early-stage DR (RR = 1.31, 95% CI [1.01, 1.68]) and early-stage retinal AEs (RR = 1.29, 95% CI [1.01, 1.66]) compared to placebo. (Sourc...
Source: Survey of Ophthalmology - July 14, 2023 Category: Opthalmology Authors: Ishani Kapoor, Swara M. Sarvepalli, David D ’Alessio, Dilraj S. Grewal, Majda Hadziahmetovic Tags: Review article Source Type: research