Frequency and characteristics of refractory dyspnea in idiopathic fibrosing interstitial pneumonia
Patients with idiopathic fibrosing interstitial pneumonias (f-IIPs) mainly suffer from dyspnea. Refractory dyspnea, defined as persistent dyspnea despite optimal treatment, could be the signal to prescribe dyspnea relievers. We aimed to examine the prevalence and characteristics of refractory dyspnea in consecutive patients with f-IIPs.Refractory dyspnea was defined by an mMRC ≥3 and also by a VAS dyspnea score≥2 at rest; the sensory and affective characteristics of refractory dyspnea (mMRC≥3) and associated quality of life (QoL) anxiety and depression were compared with non-refractory dyspnea (mMRC1-2) using the M...
Source: Respiratory Medicine - January 2, 2024 Category: Respiratory Medicine Authors: Nathalie Bautin, Juliette Ferlin, Gaelle Terce, Camille Ternynck, Victor Valentin, Lidwine Wemeau, Cecile Chenivesse Tags: Short communication Source Type: research
Inhomogeneity of ventilation in smokers and mild COPD assessed by the ratio of alveolar volume to total lung capacity
Previous studies have shown that the ratio between alveolar volume (VA) and total lung capacity (TLC) reflects ventilation heterogeneity in subjects with chronic obstructive pulmonary disease (COPD). However, the ratio and its correlation to respiratory symptoms had to our knowledge not previously been investigated in subjects with mild chronic airflow obstruction or without airflow obstruction (normal ratio FEV1/VC).The purpose of this study was to investigate potential connection between VA/TLC and respiratory symptoms, smoking habits and lung function parameters in subjects with normal spirometry and with mild chronic a...
Source: Respiratory Medicine - January 2, 2024 Category: Respiratory Medicine Authors: Hanna Ovenholm, Suneela Zaigham, Sophia Frantz, Ulf Nihl én, Per Wollmer, Viktor Hamrefors Tags: Original Research Source Type: research
Editorial Board
(Source: Respiratory Medicine)
Source: Respiratory Medicine - January 1, 2024 Category: Respiratory Medicine Source Type: research
Analysis of the quality of e-Consultations in chronic obstructive pulmonary disease
The objectives of this study were (i) to evaluate the quality of referrals; (ii) to define the characteristics of patients referred from Primary Care (PC) to the Unit of Pulmonology; and (iii) to describe differences between accepted and rejected patients. (Source: Respiratory Medicine)
Source: Respiratory Medicine - January 1, 2024 Category: Respiratory Medicine Authors: Jos é M. Álvarez-Dobaño, Carlota Rodríguez-García, Gerardo Atienza, María E. Toubes, Nuria Rodríguez-Núñez, Carlos Zamarrón, José Ángel Novo-Platas, Roi Soto-Feijóo, Elisa Landín, María Carreiras-Cuiña, Honorio J. Martínez-Martínez, Mar Tags: Original Research Source Type: research
Prevalence, characteristics and significant predictors for cardiovascular disease of patients with preserved ratio impaired spirometry: A 10-year prospective cohort study in China
Patients with preserved ratio impaired spirometry (PRIsm) have higher incidence rate of cardiovascular disease (CVD). However, few studies focused on PRIsm in China. We determined the prevalence and characteristics of patients with PRIsm in Chinese population. We also aimed to investigate the significant predictive factors of CVD in PRIsm patients. (Source: Respiratory Medicine)
Source: Respiratory Medicine - January 1, 2024 Category: Respiratory Medicine Authors: Yerui Zhang, Jie Peng, Li Liu, Huiliang Cui, Dejin Zang, Zhenguo Wu, Dachuan Guo, Xiaoyu Liu, Fanghong Lu, Jianmin Yang Tags: Original Research Source Type: research
Comprehensive clinical overview of malignant pleural mesothelioma
Malignant pleural mesothelioma (MPM) is a rare neoplasm. Its initial symptomatology often mimics tuberculosis, including pleural effusion, and is frequently treated as tuberculosis in the South Asian region, where tuberculosis predominates [1]. In 2020, there were 30,870 new cases reported worldwide, with North America accounting for 13.3 % and Europe for 44.2 %, totaling more than half of the reported cases. It is a disease with a male preponderance, with men being twice as likely as females to develop the malignancy. (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 30, 2023 Category: Respiratory Medicine Authors: Agha Muhammad Hammad Khan, Shaikh Hasan Anwer, Samad Sayed, Muhammad Atif Mansha, Yazdan Bin Kamran, Afrah Khursheed, Fahd Haroon, Niaz Hussain Soomro, Romana Idrees, Ahmed Nadeem Abbasi Source Type: research
Successful Virtual CPAP Set up in Obstructive Sleep Apnoea: A positive innovation during the pandemic
Traditionally continuous positive airways pressure (CPAP) trials for obstructive sleep apnoea (OSA) are through face to face (F2F) set up. During Covid-19 pandemic CPAP was classed as aerosol-generating hence Leeds sleep service moved to a virtual service. Patients received equipment by post followed by virtual reviews (VR). We evaluated the adherence and symptomatic benefit of postal compared to F2F method. (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 28, 2023 Category: Respiratory Medicine Authors: Gabrielle Appleby, Mark W Elliott, Rebecca Young, Dipansu Ghosh Tags: Original Research Source Type: research
Successful Virtual CPAP Set up: A positive innovation during the pandemic
Traditionally continuous positive airways pressure (CPAP) trials for obstructive sleep apnoea (OSA) are through face to face (F2F) set up. During Covid-19 pandemic CPAP was classed as aerosol-generating hence Leeds sleep service moved to a virtual service. Patients received equipment by post followed by virtual reviews (VR). We evaluated the adherence and symptomatic benefit of postal compared to F2F method. (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 28, 2023 Category: Respiratory Medicine Authors: Gabrielle Appleby, Mark Elliott, Rebecca Young, Dipansu Ghosh Tags: Original Research Source Type: research
Dietary nitrate supplementation to enhance exercise capacity in patients with COPD: Evidence from a meta-analysis of randomized controlled trials and a network pharmacological analysis
The potential effects of nitrate in patients with chronic obstructive pulmonary disease (COPD) have attracted increased research interest. However, previous clinical trials have reported inconsistent results, and consecutive meta-analyses have failed to reach a consensus. Since some randomized controlled trials have recently been conducted that can provide more evidence, we performed an updated meta-analysis. (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 27, 2023 Category: Respiratory Medicine Authors: Jing Wang, Fanchao Feng, Yang Zhao, Le Bai, Yong Xu, Yun Wei, Hailang He, Xianmei Zhou Tags: Original Research Source Type: research
Obstructive sleep apnea: Beyond the dogma of obesity!
Obstructive sleep apnea (OSA) has long been studied in patients with obesity and type 2 diabetes mellitus (T2DM), due to the fact that both disorders are commonly associated with an increased body mass index (BMI). However, a link between OSA and non-obese diabetic patients is still not very elaborated, nor heavily explored. In this review, we elucidate some proposed mechanisms for the link between OSA and diabetic patients both with and beyond obesity, shedding the light on the latter case. One such mechanism is oxidative stress, a phenomenon of reactive oxygen species (ROS) imbalance seen in both of the previously mentio...
Source: Respiratory Medicine - December 27, 2023 Category: Respiratory Medicine Authors: Joseph Abourjeili, Elio Salameh, Maya Noureddine, Pierre Bou Khalil, Assaad A. Eid Source Type: research
Prognostic factors associated with mortality in acute exacerbations of idiopathic pulmonary fibrosis: A systematic review and meta-analysis
Our results have implications for healthcare providers in making treatment decisions and prognosticating the clinical trajectory of patients, for researchers to design future interventions to improve patient trajectory, and for guideline developers in making decisions about resource allocation. (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 25, 2023 Category: Respiratory Medicine Authors: Tyler Pitre, Daniel Lupas, Ibrahim Ebeido, Alexander Colak, Mihir Modi, George V. Kachkovski, Sydney B. Montesi, Yet H. Khor, Leticia Kawano-Dourado, Gisli Jenkins, Jolene H. Fisher, Shane Shapera, Bram Rochwerg, Rachel Couban, Dena Zeraatkar Tags: Original Research Source Type: research
Impact of COPD on mortality: An 8-year observational retrospective healthcare claims database cohort study
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality. Here we present a large observational study on the association of COPD and exacerbations with mortality (AvoidEx Mortality). (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 25, 2023 Category: Respiratory Medicine Authors: Claus F. Vogelmeier, Felix W. Friedrich, Patrick Timpel, Nils Kossack, Joanna Diesing, Marc Pignot, Melanie Abram, Marija Halbach Tags: Original Research Source Type: research
Can the Rome classification of chronic obstructive pulmonary disease exacerbation severity be applied in the hospital setting?
Chronic obstructive pulmonary disease (COPD) exacerbations (ECOPDs) are crucial events in the natural history of the disease. The recent Rome proposal defines exacerbations and their grade of severity using objective parameters derived from published data. (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 23, 2023 Category: Respiratory Medicine Authors: Marianna Cometa, Antonio Ursitti, Lorenzo Pasquale Lombardo, Roberto Rana, Andrea Gardani, Marco Contoli, Alberto Papi Tags: Original Research Source Type: research
Lung function and cardiovascular risk at age 45 in a cohort of the general population
Impaired lung function is associated with cardiovascular mortality, but the origins of this association are poorly understood. We investigated associations between lung function and cardiovascular risk scores in a general population cohort of men and women aged 45 years. (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 23, 2023 Category: Respiratory Medicine Authors: Janelle Ruth C. Divinagracia, Jack Dummer, Robert J. Hancox Tags: Original Research Source Type: research
Characteristics and risk factors of interstitial pneumonia with autoimmune features
Interstitial pneumonia with autoimmune features (IPAF) has features of connective tissue disease-associated interstitial lung disease (CTD-ILD), but without meeting criteria for a specific CTD. We compared baseline characteristics, survival, and response to treatment of IPAF to both CTD-ILD and unclassifiable ILD. (Source: Respiratory Medicine)
Source: Respiratory Medicine - December 21, 2023 Category: Respiratory Medicine Authors: Sana Vahidy, Jonathan Agyeman, Boyang Zheng, Kathryn Donohoe, Nathan Hambly, Kerri A. Johannson, Deborah Assayag, Jolene H. Fisher, Helene Manganas, Veronica Marcoux, Nasreen Khalil, Martin Kolb, Christopher J. Ryerson, for the CARE-PF Investigators, Alys Tags: Original Research Source Type: research
