Clinical phenotypes of COPD and their impact on quality of life: A cross-sectional study
A Chronic Obstructive Pulmonary Disease (COPD) phenotype is a single or group of disease characteristics that describe differences between individuals based on clinically important factors such as symptoms, exacerbations, morbidity, and treatment responses. Many studies estimated the prevalence of various phenotypes, but very few studies looked into their quality of life. We aimed to estimate the prevalence of different COPD phenotypes and their disease-specific Health-Related Quality of Life (HRQoL). (Source: Respiratory Medicine)
Source: Respiratory Medicine - November 6, 2023 Category: Respiratory Medicine Authors: Jeevanandham Anandan, Dharm Prakash Dwivedi, Vishnukanth Govindaraj Tags: Original Research Source Type: research
Clinical phenotypes of COPD and its impact on quality of life. A cross-sectional study
A Chronic Obstructive Pulmonary Disease (COPD) phenotype is a single or group of disease characteristics that describe differences between individuals based on clinically important factors such as symptoms, exacerbations, morbidity, and treatment responses. Many studies estimated the prevalence of various phenotypes, but very few studies looked into their quality of life. We aimed to estimate the prevalence of different COPD phenotypes and their disease-specific Health-Related Quality of Life (HRQoL). (Source: Respiratory Medicine)
Source: Respiratory Medicine - November 6, 2023 Category: Respiratory Medicine Authors: Jeevanandham Anandan, Dharm Prakash Dwivedi, Vishnukanth Govindaraj Tags: Original Research Source Type: research
Riociguat for the treatment of pulmonary hypertension in patients with end stage renal disease
Pulmonary hypertension is a progressive condition with significant associated morbidity and mortality. The prevalence of pulmonary hypertension (PH) in patients with end stage renal disease (ESRD) has been estimated to be as high as 80 %, yet little data is available on the management of PH in this particular population [1]. While the etiology of pulmonary hypertension is often multifactorial, PH due to chronic renal failure is classified as World Health Organization (WHO) group 5 [2]. Currently, approved therapies exist primar ily for the treatment of Group 1 (pulmonary arterial hypertension) and Group 4 (chronic throm...
Source: Respiratory Medicine - November 5, 2023 Category: Respiratory Medicine Authors: Peter Cangialosi, Ewelina Wojtaszek, Alaa Omar, Radha Gopalan, Dileyni Abel, Elizabeth Tinuoye, Johanna P. Contreras, Barry A. Love, Maria Giovanna Trivieri Tags: Short communication Source Type: research
Development and validation of a nomogram for predicting hemodynamic response to balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension
Balloon pulmonary angioplasty (BPA) can effectively alleviate pulmonary hypertension in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Identifying predictors of unfavorable hemodynamic response to BPA is essential to guide clinical practice. Therefore, our objective was to construct and validate a nomogram to facilitate clinicians predicting hemodynamic response to BPA. (Source: Respiratory Medicine)
Source: Respiratory Medicine - November 5, 2023 Category: Respiratory Medicine Authors: Li Xin, Yi Zhang, Qin Luo, Qing Zhao, Tao Yang, Qixian Zeng, Qi Jin, Anqi Duan, Zhihua Huang, Meixi Hu, Sicheng Zhang, Luyang Gao, Changming Xiong, Zhihui Zhao, Zhihong Liu Tags: Original Research Source Type: research
Real-life studies and registries of severe asthma: The advent of digital technology
Asthma is a chronic disorder of the lower airways affecting over 300 million people worldwide [1]. A majority of those with asthma are treated in primary care and their asthma can be controlled with inhaled corticosteroids (ICS) and bronchodilators. Approximately 5 –10 % of patients are uncontrolled despite high dose ICS treatment or require high dose ICS treatment to remain controlled [2]. These patients often receive multiple courses of oral corticosteroids (OCS) and it is now clear that both long-term and repeated acute courses of OCS increase the risk of serious adverse effects, such as osteoporosis, metabolic diso...
Source: Respiratory Medicine - November 3, 2023 Category: Respiratory Medicine Authors: V. Urdova, L. Rogers, M. Jesenak, S.F. Seys Tags: Original Research Source Type: research
Relationship between depression severity and respiratory symptoms in US adults: A national cross-sectional study
The relationship between depression severity and cough, wheeze and exertional dyspnoea is unclear. The aim of this study was to explore this relationship. (Source: Respiratory Medicine)
Source: Respiratory Medicine - November 3, 2023 Category: Respiratory Medicine Authors: Yuefeng Sun, Yueyang Zhang, Wenzhe Bai, Xue Liu Tags: Original Research Source Type: research
The impact of elexacaftor/tezacaftor/ivacaftor therapy on the pulmonary management of adults with cystic fibrosis: An expert-based Delphi consensus
The advent of elexacaftor/tezacaftor/ivacaftor (ETI) resulted in unprecedented clinical benefits for eligible adults with CF. As a result, the question of whether chronic treatments can be safely stopped or adapted to this new situation has become a matter of great interest. Our objective was to derive a consensus among Italian experts on the impact of ETI on the current clinical management of CF lung disease. (Source: Respiratory Medicine)
Source: Respiratory Medicine - November 3, 2023 Category: Respiratory Medicine Authors: Andrea Gramegna, Stefano Aliberti, Maria Adelaide Calderazzo, Rosaria Casciaro, Clara Ceruti, Giuseppe Cimino, Benedetta Fabrizzi, Cristina Lucanto, Barbara Messore, Giovanna Pisi, Giovanni Taccetti, Paolo Tarsia, Francesco Blasi, Marco Cipolli Tags: Original Research Source Type: research
Systemic lupus erythematosus in pediatric patients: Pulmonary manifestations
The pulmonary manifestations of Systemic Lupus Erythematosus (SLE) in pediatric patients are poorly understood and the pulmonary manifestations reported from the adult population are generally extrapolated to the pediatric population. In the present work, the review of 228 files was carried out, in which the pulmonary manifestations, symptoms and antibody levels of the patients treated at the Hospital Regional de Alta Especialidad de Ixtapaluca (HRAEI), State of Mexico, Mexico, were identified. Statistical significance between groups was estimated using the Chi-square and Mann-Whitney U test. (Source: Respiratory Medicine)
Source: Respiratory Medicine - November 3, 2023 Category: Respiratory Medicine Authors: Jonathan G. Palafox-Flores, Omar E. Valencia-Ledezma, Guillermo Vargas-L ópez, Lourdes Jamaica-Balderas, Nydia Acevedo-Silva, Carlos A. Castro-Fuentes Tags: Original Research Source Type: research
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Source: Respiratory Medicine - November 1, 2023 Category: Respiratory Medicine Source Type: research
Effect of chest wall mobilization on respiratory muscle function in patients with severe chronic obstructive pulmonary disease (COPD): A randomized controlled trial
Clinical trials have demonstrated positive correlation between pulmonary function and chest wall expansion in COPD. Decrease in chest wall expansion in patients with COPD compromises rib cage mobility and functional length of respiratory muscles that ultimately jeopardize the efficacy and function of respiratory system. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 31, 2023 Category: Respiratory Medicine Authors: Amy Y.Y. Tsui, Rosanna M.W. Chau, Gladys L.Y. Cheing, Thomas Y.W. Mok, S.O. Ling, Candy H.Y. Kwan, Sharon M.H. Tsang Tags: Original Research Source Type: research
Physical status, symptoms and health-related quality of life during a severe exacerbation of COPD: Recovery and discriminative capacity for future events
This study aimed to i) investigate the recovery of muscle strength, functional capacity, symptoms, and HRQOL in patients after a severe AECOPD; ii) compare with matched patients with stable COPD (SCOPD); and iii) assess whether these assessments at hospital discharge could discriminate patients ’ risk for future events. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 31, 2023 Category: Respiratory Medicine Authors: Kirsten Quadflieg, Ana Machado, Fabiano Francisco de Lima, Anand Dederen, Marc Daenen, David Ruttens, Michiel Thomeer, Martijn A. Spruit, Chris Burtin Tags: Original Research Source Type: research
Sniff and reverse-sniff nasal respiratory pressures after exacerbation of chronic obstructive pulmonary disease: A single-center prospective study
This study examined the validity of sniff nasal inspiratory (SNIP) and reverse-sniff nasal expiratory pressures (RSNEP) for estimating respiratory muscle strength and for predicting poor life expectancy following exacerbation in patients with chronic obstructive pulmonary disease (COPD). (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 31, 2023 Category: Respiratory Medicine Authors: Tsuyoshi Ichikawa, Sakurako Tajiri, Masanori Yokoba, Yu Horimizu, Saki Yamaguchi, Akiko Kawakami, Masahiko Kimura, Tetsuri Kondo, Masato Katagiri, Minoru Toyokura Tags: Original Research Source Type: research
European pathways of care in Alpha-1 Antitrypsin deficiency
Despite initiatives to improve awareness and treatment of alpha-1 antitrypsin deficiency (AATD), country-level processes for AATD management remain unclear. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 28, 2023 Category: Respiratory Medicine Authors: Joanna Chorostowska-Wynimko, A Rembert Koczulla, Maria Sucena Tags: Original Research Source Type: research
A narrative review on the Synchrobreathe ™: A novel breath-actuated pressurised metered-dose inhaler for the treatment of obstructive airway diseases
Pressurised metered-dose inhalers (pMDIs) and dry powder inhalers (DPIs), are widely used to deliver drugs for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Incorrect use of inhalers is one of the main obstacles to achieving better clinical control. Indeed, with pMDIs, patients fail to synchronise actuation with inhalation due to a lack of coordination and with DPIs insufficient inspiratory effort compromises drug deposition in lungs. More than 50% of patients desire to switch their pMDIs and DPIs for a better device. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 27, 2023 Category: Respiratory Medicine Authors: Federico Lavorini, Omar S. Usmani, Sundeep Salvi, Kiran Rote, Vaibhav Gaur, Jaideep Gogtay Source Type: research
