Effect of chest wall mobilization on respiratory muscle function in patients with severe chronic obstructive pulmonary disease (COPD): A randomized controlled trial
Clinical trials have demonstrated positive correlation between pulmonary function and chest wall expansion in COPD. Decrease in chest wall expansion in patients with COPD compromises rib cage mobility and functional length of respiratory muscles that ultimately jeopardize the efficacy and function of respiratory system. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 31, 2023 Category: Respiratory Medicine Authors: Amy Y.Y. Tsui, Rosanna M.W. Chau, Gladys L.Y. Cheing, Thomas Y.W. Mok, S.O. Ling, Candy H.Y. Kwan, Sharon M.H. Tsang Tags: Original Research Source Type: research
Physical status, symptoms and health-related quality of life during a severe exacerbation of COPD: Recovery and discriminative capacity for future events
This study aimed to i) investigate the recovery of muscle strength, functional capacity, symptoms, and HRQOL in patients after a severe AECOPD; ii) compare with matched patients with stable COPD (SCOPD); and iii) assess whether these assessments at hospital discharge could discriminate patients ’ risk for future events. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 31, 2023 Category: Respiratory Medicine Authors: Kirsten Quadflieg, Ana Machado, Fabiano Francisco de Lima, Anand Dederen, Marc Daenen, David Ruttens, Michiel Thomeer, Martijn A. Spruit, Chris Burtin Tags: Original Research Source Type: research
Sniff and reverse-sniff nasal respiratory pressures after exacerbation of chronic obstructive pulmonary disease: A single-center prospective study
This study examined the validity of sniff nasal inspiratory (SNIP) and reverse-sniff nasal expiratory pressures (RSNEP) for estimating respiratory muscle strength and for predicting poor life expectancy following exacerbation in patients with chronic obstructive pulmonary disease (COPD). (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 31, 2023 Category: Respiratory Medicine Authors: Tsuyoshi Ichikawa, Sakurako Tajiri, Masanori Yokoba, Yu Horimizu, Saki Yamaguchi, Akiko Kawakami, Masahiko Kimura, Tetsuri Kondo, Masato Katagiri, Minoru Toyokura Tags: Original Research Source Type: research
European pathways of care in Alpha-1 Antitrypsin deficiency
Despite initiatives to improve awareness and treatment of alpha-1 antitrypsin deficiency (AATD), country-level processes for AATD management remain unclear. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 28, 2023 Category: Respiratory Medicine Authors: Joanna Chorostowska-Wynimko, A Rembert Koczulla, Maria Sucena Tags: Original Research Source Type: research
A narrative review on the Synchrobreathe ™: A novel breath-actuated pressurised metered-dose inhaler for the treatment of obstructive airway diseases
Pressurised metered-dose inhalers (pMDIs) and dry powder inhalers (DPIs), are widely used to deliver drugs for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Incorrect use of inhalers is one of the main obstacles to achieving better clinical control. Indeed, with pMDIs, patients fail to synchronise actuation with inhalation due to a lack of coordination and with DPIs insufficient inspiratory effort compromises drug deposition in lungs. More than 50% of patients desire to switch their pMDIs and DPIs for a better device. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 27, 2023 Category: Respiratory Medicine Authors: Federico Lavorini, Omar S. Usmani, Sundeep Salvi, Kiran Rote, Vaibhav Gaur, Jaideep Gogtay Source Type: research
A systematic review of methods of scoring inhaler technique
Many inhaler devices are currently used in clinical practice to deliver medication, with each inhaler device offering different benefits to overcome technique issues. Inhaler technique remains poor, contributing to reduced airway drug deposition and consequently poor disease control. Scoring inhaler technique has been used within research as an outcome measure of inhaler technique assessment, and this systematic review collates and evaluates these scoring methods. The review protocol was prospectively registered in PROSPERO (CRD42020218869). (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 27, 2023 Category: Respiratory Medicine Authors: Ruth De Vos, Alexander Hicks, Mitch Lomax, Heather Mackenzie, Lauren Fox, Thomas P. Brown, Anoop J. Chauhan Source Type: research
Burden of chronic cough on social participation, healthcare resource utilisation and activities of daily living in the Canadian Longitudinal Study on Aging (CLSA)
Chronic cough is a common troublesome condition, but it is unclear whether dry or productive chronic cough and sex, impacts the burden of cough differently. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 23, 2023 Category: Respiratory Medicine Authors: Imran Satia, Alexandra J. Mayhew, Nazmul Sohel, Om Kurmi, Kieran J. Killian, Paul M. O'Byrne, Parminder Raina Tags: Original Research Source Type: research
Atomization efficacy of a novel micro-dose mesh nebulizer (CVS-100) versus the traditional mesh nebulizer (M102) in adults with chronic obstructive pulmonary disease: A randomized non-inferiority clinical trial
To compare the atomization efficacy of a novel micro-dose mesh nebulizer (CVS-100) versus the traditional mesh nebulizer (M102) in nebulizing a combination of ipratropium bromide and salbutamol for treatment of stable moderate-to-severe chronic obstructive pulmonary disease (COPD). (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 23, 2023 Category: Respiratory Medicine Authors: Yulan Qu, Ying Gong, Li Li, Yansha Song, Yuanlin Song, Dongni Hou, Lijuan Hu Tags: Original Research Source Type: research
Is it preferable to administer a bronchodilator once- or twice-daily when treating COPD?
Night-time and early morning symptoms are common and uncomfortable in many patients with COPD, and likely to negatively influence their long-term outcomes. However, it is still debated whether it is preferable to administer long-acting bronchodilators once- or twice-daily to symptomatic COPD patients. The functional link between circadian rhythms of autonomic tone and airway calibre explains why the timing of administration of bronchodilators in chronic airway diseases can induce different effects when taken at different biological (circadian) times. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 23, 2023 Category: Respiratory Medicine Authors: Maria Gabriella Matera, Barbara Rinaldi, Concetta Ambrosio, Mario Cazzola Source Type: research
Influence of pulmonary rehabilitation on symptoms of anxiety and depression in interstitial lung disease: A systematic review of randomized controlled trials
Pulmonary rehabilitation is not detrimental to anxiety or depression for patients with ILD, and may improve symptoms of anxiety in IPF and depression in sarcoidosis. However, no conclusion can be drawn from available evidence, which is limited by heterogeneous populations/interventions, sample sizes and low prevalences of clinically-significant anxiety or depression. Further adequately powered RCTs that focus on anxiety and depressive symptoms as primary outcomes are needed. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 18, 2023 Category: Respiratory Medicine Authors: Brandon Luu, Arnav Gupta, Nicholas Fabiano, Stanley Wong, Jess G. Fiedorowicz, Lee Fidler, Risa Shorr, Marco Solmi Source Type: research
Pulmonary rehabilitation in sarcoidosis: A systematic review and meta-analysis
Exercise intolerance, muscle weakness, dyspnoea, and fatigue are frequent complications in symptomatic sarcoidosis patients. Pulmonary rehabilitation improves exercise capacity, symptoms, and quality of life in patients with chronic respiratory diseases. Our objective was to systematically determine the effects of pulmonary rehabilitation in patients with sarcoidosis. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 17, 2023 Category: Respiratory Medicine Authors: Xavier Alsina-Restoy, Rodrigo Torres-Castro, Estrella Caballer ía, Elena Gimeno-Santos, Lilian Solis-Navarro, Joel Francesqui, Fernanda Hernández-Gonzalez, Manel Ramos-Casals, Isabel Blanco, Jacobo Sellarés Tags: Original Research Source Type: research
Pulmonary rehabilitation for acute exacerbations of COPD: A systematic review
and objectives: This systematic review summarized the evidence on the effects (benefits and harms) of pulmonary rehabilitation for individuals with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 17, 2023 Category: Respiratory Medicine Authors: Jose F. Meneses-Echavez, Nathaly Chavez Guapo, Andr és Felipe Loaiza-Betancur, Ana Machado, Julia Bidonde Tags: Original Research Source Type: research
Pulmonary manifestations of amyloidosis
We describe four distinct manifestations of amyloidosis involving the lung and review their clinical, radiological and pathological features and summarize the evidence for treatment in each of these presentations. We describe alveolar-septal amyloidosis, cystic amyloid lung disease, endobronchial amyloidosis and pleural amyloidosis. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 13, 2023 Category: Respiratory Medicine Authors: Nauman A. Khan, Bharat S. Bhandari, Soma Jyothula, Daniel Ocazionez, Jamie Buryanek, Pushan P. Jani Source Type: research
Development and validation of a CT-based deep learning algorithm to augment non-invasive diagnosis of idiopathic pulmonary fibrosis
Non-invasive diagnosis of idiopathic pulmonary fibrosis (IPF) involves identification of usual interstitial pneumonia (UIP) pattern by computed tomography (CT) and exclusion of other known etiologies of interstitial lung disease (ILD). However, uncertainty in identification of radiologic UIP pattern leads to the continued need for invasive surgical biopsy. We thus developed and validated a machine learning algorithm using CT scans alone to augment non-invasive diagnosis of IPF. (Source: Respiratory Medicine)
Source: Respiratory Medicine - October 12, 2023 Category: Respiratory Medicine Authors: Manoj V. Maddali, Angad Kalra, Michael Muelly, Joshua J. Reicher Tags: Short communication Source Type: research
