Revisiting the use of high flow nasal cannula in acute exacerbation of COPD and conclusion of trial
I am writing to express my thoughts on the article titled “High-flow nasal cannula may prolong the length of hospital stay in patients with hypercapnic acute COPD exacerbation” authored by Jingen Xia, Haopu Yang, Qingyuan Zhan, Yubo Fan, and Chen Wang published in Respiratory Medicine. [1]) It was of great interest and I appreciated the authors' effort in an extensive search in the literature regarding oxygen therapy on chronic obstructive lung disease (COPD). However, we would like to raise the following two concerns in their randomized controlled trial. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 18, 2024 Category: Respiratory Medicine Authors: Toshiro Goto, Masahiro Banno, Ryota Kimura Tags: Correspondence Source Type: research
Dynamic hyperinflation is a risk factor for mortality and severe exacerbations in COPD patients
To assess if dynamic hyperinflation is an independent risk factor for mortality and severe exacerbations in COPD patients. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 16, 2024 Category: Respiratory Medicine Authors: Isabel Lorenzana, Ra úl Galera, Raquel Casitas, Elisabet Martínez-Cerón, María Alejandra Castillo, Enrique Alfaro, Carolina Cubillos-Zapata, Francisco García Río Source Type: research
Relationship of computed tomography-based measurements with symptom perception and quality of life in patients with severe asthma
This study aimed to assess the relationship between airway structural and parenchymal variables measured using chest computed tomography (CT) and subjective symptom perception and QOL in patients with severe asthma enrolled in the Korean Severe Asthma Registry. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 15, 2024 Category: Respiratory Medicine Authors: Jinyoung Jeong, Young-Hee Nam, Da Woon Sim, Byung-Keun Kim, Youngsoo Lee, Ji-Su Shim, Suh-Young Lee, Min-Suk Yang, Min-Hye Kim, So Ri Kim, Sanghun Choi, Sang-Heon Kim, Young-Il Koh, Heung-Woo Park, KoSAR investigators Tags: Original Research Source Type: research
Editorial Board
(Source: Respiratory Medicine)
Source: Respiratory Medicine - March 14, 2024 Category: Respiratory Medicine Source Type: research
Determinants of radiological patterns and severity in immunocompromised adults with Metapneumovirus infection
Human Metapneumovirus (HMPV) belongs to the Pneumoviridae family and is responsible for respiratory infections. Mild infections are well-recognized in children, while its precise impact in various categories of immunocompromised adults has not been well addressed. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 14, 2024 Category: Respiratory Medicine Authors: A. Al-Hamoud, N. Pansu, A.-L. Brun, N. Etienne, E. Farfour, V. Avettand-Fenoel, C. Rouzaud, A. Roux, F. Suarez, H. Salvator, A. Serris, E. Catherinot, O. Lortholary Tags: Original Research Source Type: research
Airway stenting for liberation from positive pressure ventilation in patients with central airway obstruction presenting with acute respiratory failure
We present a systematic review and our recent experience. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 14, 2024 Category: Respiratory Medicine Authors: Bertin D. Salguero, Abhinav Agrawal, Viren Kaul, Christian M. Lo Cascio, Greta Joy, Matsuo So, Rohit Munagala, Timothy Harkin, Udit Chaddha Tags: Original Research Source Type: research
Clinical phenotypes of nontuberculous mycobacterial disease by cluster analysis based on pulmonary function
Nontuberculous mycobacterial pulmonary disease (NTM-PD) often exhibits pulmonary function impairment, such as obstructive or restrictive pattern, with variation among patients according to the damaged lesions in the lung. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 13, 2024 Category: Respiratory Medicine Authors: Nobuyoshi Hamao, Isao Ito, Issei Oi, Masahiro Shirata, Kensuke Nishioka, Yasuyuki Hayashi, Seiichiro Imai, Toyohiro Hirai Tags: Original Research Source Type: research
Advances in co-pathogenesis of the united airway diseases
According to the concept of “united airway diseases”, the airway is a single organ in which upper and lower airway diseases are commonly comorbid. A range of inflammatory factors has been found to play an important role in the chain reaction of upper and lower airway diseases. However, the amount of research on this concep t remains limited. The underlying mechanism of the relationship between typical diseases of the united airway, such as asthma, allergic rhinitis, and chronic sinusitis, also needs to be further explored. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 12, 2024 Category: Respiratory Medicine Authors: Xinjun Xu, Jiali Yin, Yujuan Yang, Huifang Liu, Jingyi Yu, Xianghuang Luo, Yu Zhang, Xicheng Song Source Type: research
Survival and response to pulmonary vasodilator therapies in patients with chronic obstructive pulmonary disease and pulmonary vascular phenotype
The aim of the study was to describe and investigate the effect of pulmonary arterial hypertension (PAH) therapies in a cohort of patients with severe precapillary pulmonary hypertension (PH) associated with chronic obstructive pulmonary disease (COPD; PH-COPD), and to assess factors predictive of treatment response and mortality. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 10, 2024 Category: Respiratory Medicine Authors: Mathilde Steger, Matthieu Canuet, Irina Enache, Thibaut Goetsch, Aissam Labani, L éo Meyer, Guillaume Martin, Romain Kessler, David Montani, Marianne Riou Tags: Original Research Source Type: research
Systematic review of tailored dietary advice and dietitian involvement in the treatment of chronic obstructive pulmonary disease (COPD)
Evidence shows that various interventions appear to improve outcomes, but it is difficult to determine if improvements are due to nutritional intervention specifically or a rehabilitation program as a whole. More specific randomized controlled trials should be completed regarding tailored nutritional counseling and therapy in adults with COPD to determine the benefits attributable to nutritional interventions. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 9, 2024 Category: Respiratory Medicine Authors: Kylie Bell, Josh Lawson, Erika Penz, Allison Cammer Source Type: research
Implementation of virtual pulmonary rehabilitation during the COVID-19 pandemic: Experiences and perceptions of patients and healthcare providers
Pulmonary rehabilitation (PR) plays an important role in the management of symptomatic patients with chronic respiratory diseases (CRD). While studies have investigated the feasibility and efficacy of virtual PR (VPR), it is important to understand the experiences of patients and healthcare providers (HCPs) during the rapid digital health transformation that occurred in the COVID-19 pandemic. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 7, 2024 Category: Respiratory Medicine Authors: L. Verweel, T. Packham, R. Goldstein, D. Brooks, C. MacKay Tags: Original Research Source Type: research
Chronic obstructive pulmonary disease and the airway microbiome: A review for clinicians
Chronic obstructive pulmonary disease (COPD) is a complex heterogeneous disease characterized by progressive airflow limitation and chronic inflammation. The progressive development and long-term repeated acute exacerbation of COPD make many patients still unable to control the deterioration of the disease after active treatment, and even eventually lead to death. An increasing number of studies have shown that the occurrence and development of COPD are closely related to the composition and changes of airway microbiome. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 6, 2024 Category: Respiratory Medicine Authors: Lingxin Luo, Junli Tang, Xianzhi Du, Na Li Tags: Review article Source Type: research
Exhaled breath analyses for bronchial thermoplasty in severe asthma patients
Bronchial thermoplasty (BT) is a bronchoscopic treatment for severe asthma. Although multiple trials have demonstrated clinical improvement after BT, optimal patient selection remains a challenge and the mechanism of action is incompletely understood.The aim of this study was to examine whether exhaled breath analysis can contribute to discriminate between BT-responders and non-responders at baseline and to explore pathophysiological insights of BT. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 4, 2024 Category: Respiratory Medicine Authors: Pieta C. Wijsman, Annika W.M. Goorsenberg, Julia N.S. d ’Hooghe, Els J.M. Weersink, Dominic W. Fenn, Anke H. Maitland van der Zee, Jouke T. Annema, Paul Brinkman, Peter I. Bonta Tags: Original Research Source Type: research
Impact of biologics on lung hyperinflation in patients with severe asthma
In asthma, inflammation affects both the proximal and distal airways and can cause significant hyperinflation, which is thought to be a major cause of dyspnea. (Source: Respiratory Medicine)
Source: Respiratory Medicine - February 29, 2024 Category: Respiratory Medicine Authors: Mauro Maniscalco, Claudio Candia, Cecilia Calabrese, Maria D'Amato, Maria Gabriella Matera, Antonio Molino, Mario Cazzola Tags: Original Research Source Type: research
No remission in 60% of those with childhood-onset asthma - A population-based cohort followed from 8 to 28 years of age
Although remission occur, childhood-onset asthma may persist until adulthood. Since few longitudinal population-based studies have followed a cohort from childhood until adulthood, the knowledge on predictors of persistence of asthma is sparse. (Source: Respiratory Medicine)
Source: Respiratory Medicine - February 27, 2024 Category: Respiratory Medicine Authors: Linn éa Almqvist, Martin Andersson, Helena Backman, Eva Rönmark, Linnéa Hedman Tags: Original Research Source Type: research
