Leadless Pacemakers: Current Achievements and Future Perspectives
Permanent pacemakers (PPMs) have undergone rapid advancements in technology since their initial inception in the 1950s, with improvements to reduce generator size, increase battery life and quality, refine pacing algorithms and ensure lead fidelity. Despite these technological advances, the two points of weakness for the transvenous system remain the lead and the subcutaneous pocket, which can cause severe com... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 18, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
The Utility of CT Coronary Angiography in Chronic Total Occlusion Percutaneous Coronary Intervention
Predictive Performance of CTCA-derived Scores for CTO Intervention
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Scoring systems using CTCA have utilised comparisons to data obtained from invasive coronary angiography (Table 1). Fujino et al. studied 205 ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 18, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Transcatheter Tricuspid Valve Replacement: Case Selection, Technical Considerations, and Procedural Planning
Tricuspid regurgitation (TR) is a challenging disease with adverse clinical outcomes if left untreated.1,2 The prevalence and severity of TR are directly proportional to age, and the 1-year survival rate for patients with severe TR is approximately 60%.3,4 TR is classified as primary or degenerative and secondary or functional, with approximately 90% of TR being secon... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 17, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Atrial Transseptal Catheterisation: Challenging Scenarios and Techniques to Overcome Them
Transseptal catheterisation (TSC) involves the use of specialised equipment to gain access to the left atrium (LA) after crossing the interatrial septum (IAS) from the right atrium (RA) during cardiac interventional, electrophysiological and surgical procedures. The long journey to where we are today in regards to the tools and techniques used to perform this procedure started in the 19... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 14, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Cardiac Resynchronisation with Conduction System Pacing
Ventricular conduction disturbances are common in patients with heart failure. They result in loss of synchronous electrical activation and ventricular contraction.1 Despite the demonstrated benefits of biventricular pacing (BiVP), cardiac resynchronisation via BiVP remains suboptimal due to the non-physiologic fusion of paced wavefronts, and approximately 30% of BiVP recipients do not have an improvement in heart failu... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 11, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Evaluation of Subclinical Left Ventricular Systolic Dysfunction By Global Longitudinal Strain Using 2D Speckle Tracking Echocardiography in Angina With Normal Epicardial Coronary Arteries
Among patients with chest pain and normal coronary angiography, an unknown number have cardiac pain of ischaemic origin. However, normal epicardial coronary arteries have been found in approximately 20% of patients undergoing coronary angiography for chest pain evaluation.1 Over recent year... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 8, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Influence of Salt Intake on Segmental Lesions of Patients with Ischaemic Heart Disease in Sri Lanka: A Cross-sectional Study
With ongoing demographic and epidemiological changes, the burden of chronic non-communicable diseases (NCDs) is rising globally, including in Sri Lanka.1 Cardiac diseases, including ischaemic heart disease (IHD), are among the main conditions attributed to the chronic NCD burden and are one of the leading causes of hospital deaths in Sri Lanka.2,3 The ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 8, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Cardiovascular Involvement in Fabry ’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management
Fabry’s disease (FD) is a multisystem X-linked disease caused by pathogenic variants in the galactosidase-α (GLA) gene, leading to reduced α-galactosidase A (α-Gal A) enzyme activity.1 Thi s reduction is responsible for the progressive lysosomal storage of globotriaosylceramide (Gb3) and related globotriaosylsphingosine (lyso-Gb3) in several tissues and orga... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 8, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
An Approach to Non-left Main Bifurcation Lesions: A Contemporary Review
Definitions and Classifications
A bifurcation lesion is a diseased segment in a major epicardial coronary artery adjacent to or including the ostium of a significant side branch (SB). The diverse anatomical (bifurcation angle, vessel diameters) and pathological (severity, locations, and lengths of the lesions) spectrum of coronary bifurcation lesions (CBLs), along with dynamic alterations (carina shift,... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 4, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Managing Transradial Artery Access Complications During Coronary Intervention: Three Case Reports
Angiography is performed in the catheterisation laboratory to obtain images of coronary arteries to diagnose coronary artery diseases (CAD). Percutaneous coronary intervention (PCI) is an essential therapeutic invasive strategy in treating CAD. Both procedures require arterial access, including a femoral, brachial or radial approach. Compared with the femoral or brachial approac... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 1, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Revascularisation for Ischaemic Cardiomyopathy
Ischaemic heart disease is a leading cause of heart failure with reduced ejection fraction (ischaemic cardiomyopathy) and confers a dismal prognosis, with a severe reduction in both life expectancy and quality of life, despite steady advances in heart failure medical therapy.1 –3 The role of percutaneous revascularisation in managing these patients has been based on observational data and extrapolation from surgical trials.4–6 Th... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 1, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
System Delays and Target Points: An Analysis of the ST-elevation MI Response Programme in a Single Centre
Acute MI (AMI) is one of the leading causes of morbidity and mortality in the Philippines and worldwide. Across the AMI spectrum, ST-elevation MI (STEMI) carries the highest risk.
Mortality due to STEMI is influenced by various factors, including advanced age, Killip class, treatment strategy, history of AMI, diabetes, renal failure, number of diseased coronary arteries... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - August 1, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Geographic Areas of Responsibility Among Percutaneous Coronary Intervention-capable Hospitals in the Philippines
According to the Philippine Heart Association Survey, the incidence of coronary artery disease among hospitalised Filipino people is 17.5%, with an estimated mortality of 6.5%.1 It is one of the most common causes of death and is increasing. Acute coronary syndrome (ACS) is usually classified as ST-elevation MI (STEMI) or non-ST-elevation MI (NSTEMI). Because time... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - July 31, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Kawasaki Disease: A Never-ending Story?
Figure 1: Colour Doppler Flow Mapping Showing There is No Coronary Artery Obstruction
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Kawasaki disease (KD) is an inflammatory disorder that can affect the entire cardiovascular system, especially the coronary arteries, in infants (Figure 1).1 Its cause is still unknown... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - July 27, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Ablation as First-line Therapy for Atrial Fibrillation
AF is the most common sustained cardiac dysrhythmia, affecting 2 –3% of the population.1 AF is associated with significant impairments in quality of life, as well as significantly increased risk of adverse cardiovascular outcomes (e.g. heart failure, thromboembolism and premature mortality). As such, AF management is focused on improving arrhythmia-related symp toms as well as reducing morbidity associated with AF by using... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - July 27, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
