Inhaled Nitric Oxide in Patients with Cardiogenic Shock Treated with Veno-arterial Extracorporeal Membrane Oxygenation and Impella
Introduction
Combination treatment with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and Impella (ECPELLA) has been recently proposed for patients with cardiogenic shock (CS) exacerbated by biventricular cardiac dysfunction. This could simultaneously achieve a significant reduction in preload for both ventricles by right atrial (R... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - October 27, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Risk Factors for Aortic Dissection
Aortic dissection (AD) is a life-threatening condition characterized by a split between the tunica intima and tunica media of the aorta.1 The clinical classification of AD is based on the onset of symptoms and the anatomical location of the split. The condition is relatively uncommon; however, it has a high mortality rate.1 Because there is no specific examination to diagnose AD, it is rarely diagnosed at an early stage. It can affect a var... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - October 25, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Biomarkers to Improve Decision-making in Acute Heart Failure
The term ‘biomarker’ encompasses a wide-ranging subcategory of objective biological information, which can be measured accurately and reproducibly and serve as indicators of normal or pathological processes or responses to therapeutic interventions.1 In the context of acute heart failure (AHF), biomarker s play a crucial role in several aspects of the patient journey, such as facilitating prompt and accurate diagnos... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - October 25, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Vascular Access Management in Complex Percutaneous Coronary Interventions
Plato said, “The beginning is the most important part.” This adage applies to interventional cardiology, particularly to complex percutaneous coronary intervention (PCI). The success of a complex coronary program depends on meticulous vascular access. In this article, we describe various aspects related to this topic including access selection, technique, closure, and monitoring, as well as the prevent... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - October 20, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Cardiac Involvement Due to COVID-19: Insights from Imaging and Histopathology
COVID-19 (due to infection with severe acute respiratory syndrome coronavirus 2) continues to exert a profound and ongoing effect worldwide. The burden of severe acute illness on healthcare systems has increased due to the growing population of patients with lingering complications of COVID-19.1 Persisting cardiac symptoms are increasingly recognised complications, now referred to as post-acute car... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - October 18, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Unearthing Gaps in the Heart Failure Ecosystem: An Asian Pacific Society of Cardiology Online Survey
Heart failure (HF) has an estimated global prevalence of 1 –2% of the adult population and the reported prevalence in Asia is slightly higher, at 1–3%.1–3 In-hospital mortality rates range from 2% to 9.2% across the region, and reported 30-day mortality ranges from 1% in Malaysia to as high as 17% in Indonesia.3–5 The wide range of outcomes may be d ue to several factors, inclu... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - October 18, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Sex and Gender Differences in Cardiovascular Disease: A Review of Spontaneous Coronary Artery Dissection
Spontaneous coronary artery dissection (SCAD) is a cause of acute coronary syndrome (ACS) secondary to an epicardial coronary artery dissection that is not associated with atherosclerosis or trauma and is not iatrogenic.1 Myocardial injury is caused by the development of a dissection flap or intramural hematoma in the tunica media leading to coronary obstruction. Two hypo... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - October 9, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Sex and Gender Differences in Aortic Disease
The morbidity and mortality of aortic pathologies remain significant in the current era despite continued progress in understanding and treatment. Aortic aneurysm and dissection accounted for 9,317 deaths in 2020, a rate of 2.8 per 100,000 people, though this has been slowly trending down over the past two decades.1 Despite this, the true impact of both thoracic and abdominal aortic disease may be underestimated as many of these p... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - September 28, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
Non-valvular AF (NVAF) is the most common serious cardiac arrhythmia in developed countries.1 NVAF is associated with an increased incidence of stroke, heart failure and vascular dementia.2 With ischaemic stroke being the main complication, stroke prevention with oral anticoagulant therapy (OAT) has long been the cornerstone of NVAF management. Although NVAF increases the risk of stroke b... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - September 28, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
The Role of Triglyceride-rich Lipoproteins and Their Remnants in Atherosclerotic Cardiovascular Disease
Over the past decade, triglyceride-rich lipoproteins (TRLs) and their remnants have emerged as novel potential targets for managing dyslipidaemia and atherosclerotic cardiovascular disease (ASCVD).1 Conclusive clinical evidence has linked LDL cholesterol (LDL-C) with the risk for ASCVD. Numerous studies in a variety of patient populations have established that statin thera... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - September 28, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Tricuspid Regurgitation: Disease State and Advances in Percutaneous Therapy
“It should be possible to compare this recoil of the blood in the veins to the swelling and turbulence of flooding waters from the rising seas.”
– An early account of venous pulsations in right heart failure by Homberg, Paris, 1704.1
Severe tricuspid regurgitation (TR), which affects 1.6 mill ion people in the US, leads to progressive right ventricular (RV) dilation and failure if left untreated.2,3 ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - September 28, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Technical Considerations for Percutaneous Tricuspid Paravalvular Leak Closure
Paravalvular regurgitation is a known complication in 5 –17% of prosthetic valve replacements, and may be treated with either surgery or percutaneous repair in patients with refractory heart failure and/or haemolytic anaemia.1 Percutaneous paravalvular leak (PVL) closure is supported by a class 2a recommendation in the 2020 American College of Cardiolo gy/American Heart Association (ACC/AHA) valvular... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - September 28, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Association Between Coronary Artery Calcium Score and Left Ventricular Diastolic Dysfunction in Patients with Hypertension
Coronary artery calcium (CAC) is an established marker of subclinical atherosclerosis and an independent predictor of future coronary artery disease (CAD).1,2 The CAC score, determined using non-contrast coronary CT (CCT), can assist in cardiovascular (CV) risk assessment and clinical decision-making.3 The presence and extent of CAC are associated with a... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - September 26, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Septal and Conduction System Pacing
Specific conduction system pacing is a recent development in efforts to restore normal electrical conduction in the heart by means of artificial pacing.1 It can be achieved by specific His or left bundle branch (LBB) pacing and, possibly, by non-specific high right ventricular (RV) septal pacing. There are several clinical situations in which conduction pacing is clearly indicated.
Abnormal conduction-induced cardiomyopathy refers to left... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - September 26, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Narrative Review of Postural Orthostatic Tachycardia Syndrome: Associated Conditions and Management Strategies
Postural orthostatic tachycardia syndrome (POTS) is a disorder that can present with various non-specific symptoms, although it is primarily characterized by symptoms of orthostatic intolerance lasting at least 3 –6 months. Clinically, this condition is defined as:
orthostatic intolerance associated with an increase in heart rate of 30 BPM (>40 BPM for adolescent... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - September 19, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
