Appropriateness of Antiplatelet Pretreatment in Non-ST-segment Elevation Acute Coronary Syndrome: Differences Between Unstable Angina and Acute Myocardial Infarction
Objective: To evaluate the appropriateness of antiplatelet pretreatment in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). To determine whether the appropriateness differs between patients with unstable angina and those with acute myocardial infarction.
Materials and methods: This pro... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 25, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
LDL-C Reduction in Diabetic Patients after Percutaneous Coronary Intervention: Is There any Difference with Non-diabetic?
Objective: The clinical benefit of lowering LDL cholesterol (LDL-C) in secondary prevention is well known from clinical trials, especially in diabetic patients. The aim of this study was to evaluate LDL-C reduction in diabetic versus non-diabetic patients after percutaneous coronary intervention in clinical praxis.
Materials and methods: An observational... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 25, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
The Predictive Value of NT-proBNP across Glomerular Filtration Rate Subsets in Heart Failure Treated Patients
Objective: We aimed to assess the predictive value of high NT-proBNP for all-cause long-term mortality in heart failure (HF) patients for different subsets of renal function defined by the estimated glomerular filtration rate (eGFR).
Materials and methods: HF patients admitted consecutively to our cardiology department from 2011 to 2014 were retrospectively included... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 25, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Artificial Intelligence – Advisory or Adversary?
Artificial intelligence (AI) leverages computers and machines capable of performing high-level executive functions, mimicking human intelligence. Machine learning (ML) is a branch of AI capable of improving itself by learning from data, identifying patt erns and making decisions without being explicitly programmed to do so. AI is already part of everyday life and used in areas including healthcare, banking systems and industry.... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 24, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Coronary Artery Disease in Patients with Severe Mental Illness
Approximately 1% of the UK population have a diagnosis of a severe mental illness (SMI). A diagnosis of SMI is associated with a decrease in life expectancy of up to 20 years compared with the general population.1 Although part of this mortality gap is due to complications of psychiatric disease, such as suicide, the major cause of death is cardiovascular (CV) disease (CVD).2,3
The increased risk of CVD in patie... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 24, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Severe Acute Thrombocytopenia After Treatment with Tirofiban: A Case Series Approach
Glycoprotein IIb/IIIa inhibitors (GPI) are an adjuvant therapy for the treatment of patients with acute coronary syndromes before, during and after percutaneous coronary intervention (PCI).1 The main adverse reactions are bleeding and thrombocytopenia in 1 –2% of cases, the latter being a rare presentation but with potential catastrophic consequences. Although the pathogenesis of this phenome... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 24, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Clinical Pathways Guided by Remotely Monitoring Cardiac Device Data: The Future of Device Heart Failure Management?
Remote monitoring (RM) of implanted cardiac devices to detect device-related issues and clinically relevant arrhythmias is well established and endorsed by international guidelines.1 Existing infrastructure and technology facilitate passive transmission of device-monitored health data from a patient ’s own home to their healthcare provider, allowing for real-tim... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 24, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
How to Improve Clinical Outcomes and Reduce Cardiovascular Risk in Older People with Cardiovascular Disease: Bridging Evidence Gaps
The geriatric population is rapidly increasing and is greatly impacted by cardiovascular disease. Thus, it becomes essential to ‘geriatricise’ the cardiologist through the dissemination of geriatric cardiology. In the early days of geriatric cardiology, it was questioned whether it was simply cardiology ‘well done’. Today, some 40 years later, i... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 24, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
The 2022 European Society of Cardiology Cardio-oncology Guidelines in Focus
The publication of the 2022 European Society of Cardiology (ESC) cardio-oncology guidelines provides an important milestone in the cardiovascular care of adult cancer patients and adult survivors of childhood and adolescent cancers.1 The recommendations were developed through a concerted international effort, with collaboration from the ESC, the European Society for Therapeutic Radiology and Oncology... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 21, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Fulminant Myocarditis: When One Size Does Not Fit All – A Critical Review of the Literature
The definition of ‘fulminant’ myocarditis (FM) was first used in 1991 to describe an uncommon, severe form of biopsy-proven myocarditis that had cardiogenic shock (CS) with acute left ventricular failure as the initial presentation.1 Th e term FM is still used to define the most acute and life-threatening presentation of myocarditis, characterised by sudden onset and a rapid clinical d... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 20, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Long-term Outcomes for Drug-eluting Balloons versus Drug-eluting Stents in the Treatment of Small Vessel Coronary Artery Disease: A Systematic Review and Meta-analysis
Small vessel coronary artery disease (SvCAD) is a significant risk factor for adverse events in percutaneous coronary intervention patients. It is often diffuse and multivessel on presentation and confers worse outcomes with higher rates of major adverse cardiac events (MACE) and target lesion failure after in... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 20, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies
Over the past decade, the role of the gut microbiota in the pathogenesis of cardiovascular diseases has gained significant attention. Beyond its influence in shaping gut metabolism, these microbes also affect non-gut organs, which in turn has wide clinical and therapeutic implications.
The Gut Microbiota
The term ‘gut microbiota’ was coined by Joshua Lederberg in 2001 and refers to the dynamic e... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 19, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Artificial Intelligence in Medicine: Neither Intelligent nor Artificial?
When Schuppanzigh ’s quartet first played Beethoven’s first Razumovsky Quartet (opus 59.1), they laughed and were convinced the composer was playing a trick on them. “Surely, you do not consider this music?” asked the bemused violinist Felix Radicati. “Not for you,” replied Beethoven, “but for a later a ge.”
When being asked at congresses and medical meetings what I consider as the fundamental changes in... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 19, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Artificial Intelligence for the Detection and Treatment of Atrial Fibrillation
AF, the most common clinically relevant cardiac arrhythmia, is expected to affect>5 million Americans by 2050.1 The diagnosis is frequently associated with other cardiovascular comorbidities, including hypertension, obesity and sleep apnoea, and AF is an important risk factor for stroke, heart failure and overall mortality.2 –4 Although treatment is available, many people remain untreated becau... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 19, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Perspectives and Future Directions of Anticoagulant Therapy in Coronary Artery Disease Patients
The use of antiplatelet agents to prevent ischaemic events in atherosclerotic cardiovascular diseases is well established. Coagulation pathways are involved in platelet activation and contribute to thrombus formation irrespective of whether this is within the arterial or venous circulation. The usefulness of oral anticoagulants (OACs), particularly non-vitamin K antagonist OACs (N... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 18, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
