Streptococcus mitis Tricuspid Valve Infective Endocarditis Accompanied by Haematological Management Challenges
Tricuspid valve infective endocarditis (TVIE) is strongly associated with IV drug use (IVDU); device implants also represent significant risk factors. Congenital anomalies, including ventricular septal defect (VSD), predispose patients to TVIE.1 Streptococcus mitis is a mesophilic alfa-haemolytic germ inhabiting the oro- and nasopharyngeal cavities and has been impl... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 6, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Sudden Cardiac Death in Ischaemic Cardiomyopathy and the Primary Prevention ICD: Time for a More a Personalised Approach?
International guidelines recommend primary prevention ICDs (PPICDs) in patients with symptomatic heart failure and a left ventricular ejection fraction (LVEF) (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 5, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Patent Foramen Ovale-associated Stroke and COVID-19 Vaccination
Case –control studies have shown an association between patent foramen ovale (PFO) and cryptogenic stroke, which was observed particularly in patients younger than 55 years without conventional risk factors. The role of PFO closure in preventing stroke recurrence had been uncertain for many years, unt il four randomised clinical trials in 2017 and 2018 unequivocally demonstrated a benefit, with the number needed t... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 5, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: Clinical Outcomes
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterised by fibrothrombotic material mechanically obliterating major pulmonary arteries, resulting in increased pulmonary vascular resistance (PVR), progressive pulmonary hypertension (PH) combined with a microscopic pulmonary vasculopathy, right ventricular (RV) failure and premature death.1,2 The survival of patien... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 5, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Sex Differences in Outcome and Prescribing Practice in ST-elevation MI Patients with Multivessel Disease and Incomplete Revascularisation
Women have a poorer prognosis following ST-elevation MI (STEMI) than men.1 –7 Although sex-based differences in post-STEMI outcome are well documented, the reasons for these poorer outcomes in women are less well defined, which limits our ability to close this sex-based outcome gap. The role played by differences in the anatomical complexit... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 4, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Noise, Air, and Heavy Metal Pollution as Risk Factors for Endothelial Dysfunction
Environmental stressors, such as noise, air or heavy metal pollution, represent important risk factors for the development and progression of cardiovascular disease (CVD).1 –5 The WHO estimates that at least 1.6 million healthy life years are lost every year in western European countries alone due to the exposure to environmental noise. Additionally, within the last years, the GBD study establis... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 4, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Imaging in Heart Failure with Preserved Ejection Fraction: A Multimodality Imaging Point of View
Heart failure (HF) with preserved ejection fraction (HFpEF) is an important global health problem. HFpEF, which is mainly common in older patients with hypertension and/or obesity, is closely associated with left ventricular (LV) hypertrophy (LVH). Patients with HFpEF usually present with symptomatic HF despite a normal LV ejection fraction (LVEF) but have similar morbidity and m... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 4, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Mechanical Circulatory Support for Complex High-risk Percutaneous Coronary Intervention
In the modern cardiac catheterization laboratory, technological and procedural innovations increasingly permit the performance of ever more cognitively and technically ‘complex’ and ‘high-risk’ percutaneous coronary interventions (PCI).1 Decades of stepwise advances in interventional technology, techniques, and pharmacology have improved the safety and efficacy of PCI in progressively mor... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - April 4, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Cerebral Embolic Protection Devices: Current State of the Art
Transcatheter aortic valve replacement (TAVR) is a major advancement in the treatment arsenal for elderly patients with severe aortic stenosis with intermediate-to-high surgical risk. According to recent trial studies, TAVR carries similar or superior clinical outcomes compared to surgical aortic valve replacement (SAVR) even in a population with a low surgical risk, thereby, encompassing the younger and low-risk ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 31, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Cancer and Postradiotherapy Cardiotoxicity: How to Face Damage in Women ’s Hearts?
Cancer and cardiovascular disease are the two main causes of death worldwide in both men and women.1 One in 8.3 deaths was attributed to coronary heart disease (CHD) in women, whereas one in 31.5 deaths was attributed to breast cancer (BC) in 2017.2
In the past deca des, survival rate in cancer patients has substantially improved due to new treatments and developments in radiation therapy (RT).... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 29, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Procedural and Technological Innovations Facilitating Ultra-low Contrast Percutaneous Coronary Interventions
In the modern era, patients being treated with percutaneous coronary interventions (PCI) present an increasingly challenging profile in terms of both comorbidities and anatomical complexity. In this context, there is a growing awareness that performing ultra-low-dose contrast PCI contributes to increased safety and quality of the intervention.
Until recently, ultra-l... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 29, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Acute Decompensated Heart Failure with Preserved Ejection Fraction: Do the Asian Phenotypes Fit?
Acute decompensated heart failure (ADHF) is a global health burden affecting millions of people across the globe and is associated with high rates of mortality and morbidity.1 Furthermore, ADHF poses a great economic challenge linked to high rehospitalisation rates.2 Heart failure (HF) with preserved ejection fraction (HFpEF) accounts for more than half of total ADHF-related admi... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 28, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
The Incremental Value of Functional Testing for Acute Chest Pain Assessment in the Context of High-sensitivity Troponin T
For patients undergoing evaluation for suspected acute coronary syndrome, with clinical presentation and troponin profile that is not thought consistent with MI and therefore not undergoing early angiography, current guidelines recommend subsequent functional cardiac testing. The basis for this recommendation, however, arises from an era where biomarkers ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 28, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Primer on Machine Learning in Electrophysiology
Artificial intelligence (AI) has recently gained popularity, becoming a buzz word in the fields of science, technology, engineering and mathematics. AI aims to teach a computer how to replicate human intelligence to perform human tasks. Machine learning (ML) is a subset of AI that uses data to teach a machine how to imitate human behaviour. The overall goal of ML is to have a computer perform a task that a human performs, based... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 28, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Coronary Microvascular Spasm: Clinical Presentation and Diagnosis
Professor Maseri was a pioneer who blazed a trail in the field of coronary vasomotion abnormalities from its dawning age and was one of the most prominent physician-scientists represented in the history of the field.1,2 More than 40 years ago, he demonstrated that myocardial ischaemia can be caused by coronary vasomotion abnormalities, such as coronary vasospasm and distal coronary constriction, even in the ab... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 21, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
