Global Public Health Burden of Heart Failure: An Updated Review
Heart failure (HF) is a clinical syndrome with different underlying aetiologies rather than being a specific disease. Traditionally, HF has been defined as a condition where there is a reduced ability of the heart to pump and/or fill with blood, or alternatively an inadequate cardiac output caused by a structural or functional abnormality, or adequate cardiac output secondary to compensatory neurohormonal activa... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - July 27, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Combination of Laser Atherectomy and Super High-pressure Non-compliant Balloon to Treat Stent Under-expansion in Cases of Failed Interventional Options
Stent under-expansion carries a major risk of stent thrombosis with serious consequences if left untreated. There have been reports of using rotational atherectomy (ROTA) to overcome stent under-expansion, but the procedure holds many risks. Intravascular lithotripsy (IVL) can only be carried out if the balloon passes through... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - July 25, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Left Main Percutaneous Coronary Revascularization
Given the rapid developments in drug-eluting stent platforms and the adoption of bifurcation techniques, percutaneous coronary intervention (PCI) of left main (LM) diseasehas become a common procedure in modern day catheterization laboratories.1,2 In fact, percutaneous revascularization of patients with LM disease and a low SYNTAX score has been recommended in the most recent American College of Cardiology and European Societ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - July 20, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Major Adverse Cardiovascular Event Risk Prediction in Asian Patients After Myocardial Infarction: A Novel, Dynamic, Machine-learning Approach
We have witnessed remarkable advances in cardiovascular therapeutics over recent decades, yet adverse outcomes related to cardiovascular diseases (CVD) are on the rise.1 CVD accounts for one-third of global mortality, being the cause of death of 17.9 million people in 2015.2 Pathophysiological factors underlying CVD onset and progressi... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - July 3, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Heart Failure and Cardiac Device Therapy: A Review of Current National Institute of Health and Care Excellence and European Society of Cardiology Guidelines
Clinical guidelines are the cornerstone of current medical practice, providing high-quality, up-to-date advice for clinicians. Not only do they promote equity in clinical care through evidence-based medicine, but also they serve as important educational tools. In this article, we compare the most widely used clinical car... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 30, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition: The Big Step Forward in Lipid Control
The discovery of proprotein convertase subtilisin/kexin type 9 (PCSK9) and its translation to an approved target of therapy in a span of a mere 12 years highlights how genetic insights can be leveraged into intelligent therapeutic innovation.1 –3 The journey started in 2003, when Abifadel et al. discovered a cohort of French individuals with autosomal dominant hypercholesterolaemia... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 28, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
An Overview of the PRESYON 4 Trial and Its Impact on Practice
Worldwide, the prevalence of non-communicable diseases, including cardiovascular diseases (CVDs), is increasing at a staggering rate. CVD is the leading cause of morbidity and mortality, attributable to an increase in risk factors such as obesity, diabetes and hypertension.1 The Philippines is not exempt. In the Philippines, the most common causes of morbidity and mortality in the four decades before the 1980s wer... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 27, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Contemporary Review of the Management of Left Ventricular Thrombus
Left ventricular thrombus (LVT) is a well-known complication of acute MI (AMI) and non-ischaemic cardiomyopathies.1 The presence of LVT increases the risk of embolic complications, such as stroke or systemic embolisation, hence treatment with oral anticoagulation is often indicated.2 The European and American guidelines recommend a period of anticoagulation in patients with AMI and LVT.3,4 Currently, the oral... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 27, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
A Case of Primary Cardiac B-cell Lymphoma Diagnosed with Cardiac MRI
Primary cardiac tumors are extremely rare, having an incidence of 0.001 –0.28% in an autopsy series.1 By contrast, metastatic tumors to the heart are some 30-fold more common.2 The most frequent clinical manifestations associated with primary cardiac lymphoma (PCL) are pericardial effusion, heart failure, and atrioventricular block.3 Due, in part, to late recognition, as well as a lack of a standard approach... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 26, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Cardiometabolic Risk Factors and COVID-19 Outcomes in the Asia-Pacific Region: A Systematic Review, Meta-analysis and Meta-regression of 84,011 Patients
COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has resulted in more than 6 million deaths worldwide in 226 countries as of 13 April 2022.1 Patients with cardiometabolic risk factors (CMRF) have an increased risk of developing severe COVID-19 disease and mortality. Emerging literature has sh... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 23, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Procedural Adaptations to Avoid Haemodynamic Instability During Catheter Ablation of Scar-related Ventricular Tachycardia
Catheter ablation for medication-refractory scar-related ventricular tachycardia (VT) was first performed in 1983, inspired by earlier VT procedures in which endocardial arrhythmogenic substrate was mapped and surgically resected.1,2 VT ablation became more common in the late 1980s with the advent of radiofrequency energy ablation, which enhanced procedur... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 22, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Transvenous Lead Extraction: Work in Progress
Cardiac implantable electronic devices (CIEDs) are central to the management of arrhythmias and to mitigating the risk of arrhythmia. In the UK alone,>40,000 devices are implanted each year.1 The extraction of leads is essential to the long-term management of CIEDs, establishing transvenous lead extraction (TLE) as a life-saving procedure. TLE has undergone an incredible evolution since its inception (Figure 1). Early methodo... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 19, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Validity of Self-reported Self-Care Assessment and Determinants of Self-Care Practices in Older Patients with Heart Failure
The number of patients with heart failure (HF) in Japan is estimated to reach 1.3 million by 2030 as the population declines and the proportion of the population aged ≥65 years increases rapidly.1 Approximately 40% of patients with HF are hospitalised within a year and preventing rehospitalisation has become an urgent issue.2,3
In addition to pharmacot... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 16, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Is It Really Safe to Discontinue Antiplatelet Therapy 12 Months After Percutaneous Coronary Intervention in Patients with Atrial Fibrillation?
AF is the most common cardiac arrhythmia worldwide. The estimated prevalence among adults is 2 –4%, and the lifetime risk of developing AF is one in three individuals.1–3 AF is associated with stroke, increasing the risk four- to five-fold while accounting for 20–30% of ischaemic strokes.4,5 In addition, embolic strokes associated with... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 13, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
Clinical and Radiographic Predictors of Successful Coronary Angiography Through Right Radial Artery Access
In recent years, radial access approaches have gained more attention than traditional femoral access approaches because of better patient satisfaction and safety profiles with earlier mobilisation and shorter hospitalisation durations. Moreover, the use of the radial approach has become the first-line choice for performing percutaneous coronary intervention in acute cor... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - June 13, 2023 Category: Cardiology Authors: dbarot525787 Source Type: research
