Dovetailing Intra-coronary Imaging and Physiology … the True Gold Standard
Chronic coronary disease and resultant chest pain can often be treated with medical therapies to minimise symptoms and improve quality of life. However, the case presented by Volleberg et al. highlights the intrinsic complexities of assessing and treati ng coronary artery disease in those with intrusive symptoms and failed medical therapy.1 The case provides several insights that reaffirm the importanc... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - January 19, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Torrential Tricuspid Regurgitation Treated with TricValve
A 52-year-old man was being managed for symptomatic torrential tricuspid regurgitation (TR). He had Marfan ’s syndrome with severe aortic regurgitation and extensive thoracoabdominal aortic aneurysms and dissections for which he had undergone multiple interventions. These included a Bentall procedure in 2002, thoracoabdominal aorta repair in 2011, aortic arch repair in 2012, thoracic endovascular aorti c repair (TEVAR) ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 21, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
The DELIVER Trial: the Beginning of the End of Ejection Fraction Tyranny
‘The DELIVER trial has Delivered!’, declared consultant cardiologist Theresa McDonagh when she discussed the trial findings at the European Society of Cardiology Congress in Barcelona on 27 August, 2022 with principal investigator Scott Solomon when he presented the results.
The Dapagliflozin Evaluation to Improve the Lives of Patients with Preserved Ejection Fraction Heart Failure (DELIVER) trial was ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 20, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Artificial Intelligence and Cardiovascular Risk Prediction: All That Glitters is not Gold
Cardiovascular diseases (CVDs) still represent the most common cause of morbidity and mortality worldwide, despite the impressive improvements in patient prognosis achieved in the last decades through several innovations in the diagnosis and management of a broad spectrum of CVDs.1 –7 Nonetheless, the growing prevalence of cardiovascular risk factors and the better prognosis of patients ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 20, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
SECURE, ADVOR and REVIVED: Clinical Trials Presented at ESC 2022
A total of 36 studies in 10 Hot Line sessions were presented at this year ’s European Society of Cardiology Congress. What was notable in this 2022 edition compared to prior meetings was the increased number of investigator-initiated trials, of which I have selected three important ones for a brief discussion given their novel findings and potential impact on clinical p ractice.
I will begin with the Secondary P... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 19, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Under-representation of Women as Proceduralists and Patients in TAVR and TMVr Procedures: Data, Implications and Proposed Solutions
Women are under-represented in cardiology workforces.1 –4 This under-representation has an impact at the physician and patient level and has been linked to poor outcomes for women with cardiovascular diseases.1,5 Available data on transcatheter aortic valve replacement (TAVR) and other structural interventional operators suggest that women accoun... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 19, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Multimodality Imaging to Explore Sex Differences in Aortic Stenosis
Aortic stenosis (AS) is the most common valvular heart disease in Western countries, with a prevalence that increases with age.1 –3 Aortic valve calcification (AVC) and fibrosis are the main pathophysiological changes that lead to degenerative AS. However, the relative contribution that each pathophysiological mechanism makes to the development of severe AS differs between men and women. For a similar degree ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 19, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Is It Time to Call ‘Code Blue’ on Nursing Infrastructure? A Nurse’s Perspective from the COVID-19 Front-line
‘Why did you become a nurse?’ This is a question nearly every one of us in the profession hears, from when we first started nursing school to when we are decades into our careers. It can be a deeply personal and loaded question; it also becomes a question we ask ourselves when faced with adversity on the job. Nurses work through a unique set of challenges that have le... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 19, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Polypharmacy in Older People With Heart Failure: Roles of the Geriatrician and Pharmacist
The incidence and prevalence of heart failure (HF) is on the rise due to an ageing population.1 It is estimated that there are around 64.3 million people with HF worldwide.2 In view of more timely diagnosis and more effective management of ischaemic heart disease, hypertension, valvular heart disease and HF itself, the average age of HF cohorts is increasing.3 For a long time, the mains... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 19, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Treatment of Severe Aortic Valve Stenosis: Impact of Patient Sex and Life Expectancy on Treatment Choice
In adults with severe aortic stenosis (AS) there are two steps in the decision-making process. First, is there an indication for aortic valve replacement (AVR)? Second, what type of valve replacement is most appropriate in this patient? Both European Society of Cardiology/European Association of Cardio-Thoracic Surgery (ESC/EACTS) and Am... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 6, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Most Recent Trials and Advances in Hypertension
Measurement of Blood Pressure
The 2018 European Guidelines on the management of hypertension recommend that the diagnosis of hypertension should not only be based on office blood pressure (BP) but also on out-of-office measurements such as ambulatory or home BP monitoring.1 These recommendations were directed to enable more accurate diagnosis, particularly in the context of white-coat and mas... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - December 6, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Effects of High- or Moderate-intensity Rosuvastatin on 1-year Major Adverse Cardiovascular Events Post-percutaneous Coronary Intervention
Atherosclerosis is the basis of adverse cardiovascular events. It has been shown that endothelial damage and inflammation play critical roles in the development and progression of atherosclerosis. Endothelial dysfunction refers to an impairment of the ability of the endothelium to properly maintain vascul... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - November 29, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Fontan-associated Liver Disease in Adults: What a Cardiologist Needs to Know. A Comprehensive Review for Clinical Practitioners
The Fontan operation is a surgical repair for a broad spectrum of severe congenital heart defects in which the restoration of the function of both ventricles is not feasible. The concept of the Fontan circulation has continuously evolved over the course of five decades with substantial technical modifications. Stil... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - November 29, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Advanced Steering Maneuvers for Special Situations in Mitral Valve Transcatheter Edge-to-edge Repair
Mitral regurgitation (MR) is the most common valvular heart disease throughout the world, present in approximately 10% of people aged ≥75 years, with an estimated case prevalence of 4 million in the US alone.1,2 Moderate to severe MR is associated with significantly high mortality, which can be as high as 20% at 1 year and 50% at 5 years.3–5... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - November 18, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
Ventricular Assist Devices: Challenges of the One-device Era
Despite improvements in survival of patients with heart failure (HF) attributed to neurohormonal and device therapies, some patients with advanced HF may still need and benefit from heart transplantation or durable left ventricular assist device (LVAD) support.
LVADs should be considered in patients with INTERMACS profile of 2 –4 and in those with INTERMACS profiles of 5–6 who hav... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - November 18, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research
