Secondary Mitral Regurgitation: Diagnosis and Management
Mitral regurgitation (MR) is the most common type of valve disease in developed nations and affects more than 2 million people in the US.1 It is seen in approximately one-third of patients with chronic heart failure, and contributes to the progression of disease and a worsening prognosis.2 In patients aged ≥50 years, yearly mortality rates for moderate to severe MR range from 3% to 6%.3MR can be caused by an abnormalit... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 15, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Remarkable Reviewers in 2023
Henry Oldenburg, the first secretary of the Royal Society, introduced the concept of peer review for assessing submissions to the eminent journal Philosophical Transactions of the Royal Society in 1660. Since then, the quality and impact of articles published in scientific journals are heavily dependent on knowledgeable and truly committed reviewers. Arrhythmia& Electrophysiology Review is determined to obtain outstanding reviews for every s... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 11, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

What Cannot be Missed: Important Publications on Electrophysiology in 2023
A list of the most important articles on arrhythmia published in 2023.Healey JS, Lopes RD, Granger CB, et al. Apixaban for stroke prevention in subclinical atrial fibrillation. N Engl J Med 2024;390:107 –17.Crossref | PubmedKirchhof P, Toennis T, Goette A, et al. Anticoagulation with edoxaban in patients with atrial high-rate episodes. N Engl J Med 2023;389:1167–79. Crossref | PubmedSohns C, Fox H, Mar... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 11, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Consequences and Management of Excessive Ostial Stent Protrusion: A Case Report
Aorto-ostial intervention presents complex and unique challenges due to high calcium content, fibrous plaque and increasing elastic recoil related to the muscular elastic tissue. There are also technical problems, such as catheter engagement, poor guide catheter support and pressure damping. Additionally, ostial anatomic variations, the coronary ostium irregular shape and limitations of 2D angiog... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 11, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Intracardiac Echocardiography-guided Left Atrial Appendage Occlusion
Despite multiple advances in treatment strategies, the incidence and prevalence of AF continues to increase worldwide, affecting up to 4% of the population.1 –4 AF is associated with significant morbidity and mortality, leading to a notable burden on healthcare systems represented by more hospitalisations, an increased incidence of stroke and loss of productivity. The estimated annual healthcare cost of AF t... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 8, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Artificial Intelligence for the Interventional Cardiologist: Powering and Enabling OCT Image Interpretation
It is now well established that intracoronary imaging (ICI) in percutaneous coronary intervention (PCI) can improve clinical outcome measures compared with angiography-guided procedures.1,2 Intravascular optical coherence tomography (IVOCT) is a form of ICI that uses near-infrared light to generate high-resolution, cross-sectional, and 3D volumetric images of the vesse... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 8, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History?
Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History? Catheter ablation of AF requires ablation of the posterior wall in the left atrium. With conventional thermal ablation modalities, the lesion can spread past the myocardium to affect adjoining structures, which is a common source of certain AF complications. One such structure is the oesophagus, which is immediately adjacent to the left atrial posterior wall.1 Oesophageal damag... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 6, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Initiation and Up-titration of Guideline-directed Medical Therapy for Patients with Heart Failure: Better, Faster, Stronger!
Initiation and Up-titration of Guideline-directed Medical Therapy for Patients with Heart Failure: Better, Faster, Stronger! According to the current universal definition, heart failure (HF) is a clinical syndrome with signs and symptoms secondary to a functional and/or structural cardiac abnormality corroborated by the elevation of natriuretic peptides (NP) or objective evidence of cardiogenic pulmonary or systemic congestion.1 It is typically classified based on the left ... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 5, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Left Atrial Appendage Occlusion: British Cardiovascular Intervention Society and British Heart Rhythm Society Position Statement
Left Atrial Appendage Occlusion: British Cardiovascular Intervention Society and British Heart Rhythm Society Position Statement AF is the most common abnormal heart rhythm. It increases the risk of stroke by five times. Percutaneous left atrial appendage occlusion (LAAO) was developed as an alternative to oral anticoagulation. The procedure has been studied in large international randomised trials and registries and was approved by the National Institute for Health and Car... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 5, 2024 Category: Cardiology Authors: agne_angelides619969 Source Type: research

Early Onset Severe Aortic Stenosis Presenting with Recurrent Ventricular and Supraventricular Arrhythmia and Postoperative Stroke in a 44-year-old Man with Uncontrolled Rheumatoid Arthritis
Early Onset Severe Aortic Stenosis Presenting with Recurrent Ventricular and Supraventricular Arrhythmia and Postoperative Stroke in a 44-year-old Man with Uncontrolled Rheumatoid Arthritis Aortic stenosis is a valvular heart disorder often seen in older people which causes left ventricular obstruction, causing symptoms such as syncope, angina, dyspnoea and heart failure symptoms. Common aetiologies include congenital valve problems, such as unicuspid or bicuspid valve, cal... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - March 1, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

The Pink Tax: Sex and Gender Disparities in Peripheral Artery Disease
Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in women, accounting for nearly one of every three deaths in women in the US annually.1 Peripheral artery disease (PAD) is a significant marker of systemic arteriosclerosis associated with increased all-cause, cardiovascular (CV), and cerebrovascular mortality, but it remains largely underrecognized and undertreated among wom... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - February 23, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Hypertonic Saline to Achieve Hyperdiuresis: A Case Report
Despite the availability of various treatment strategies, managing acute decompensated heart failure (ADHF) remains a challenge. Diuretics remain the mainstay of treatment in patients with ADHF. However, diuretic resistance (DR) can commonly occur following chronic diuretic use, leading to difficulty in diuresis.Here we report our experience in successfully using hypertonic saline for hyperdiuresis in a critically ill... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - February 20, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Panel Discussion: Non-cardiac Surgery Interventions on Patients Receiving Impella Support
Discussion: Non-cardiac Surgery Interventions on Patients Receiving Impella Support Presentation 1: Non-cardiac Interventions in Patients With High Profile Temporary Transvalvular PumpsPresented by: Jaime Hernandez-Montfort, MDDr Hernandez-Montfort opened by presenting the discussion goals as follows:to emphasise the unmet need among high-risk patients with impaired myocardial function requiring non-cardiac interventionsto review case-based programmatic approaches to p... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - February 14, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Panel Discussion: Advanced Surgical Uses of Percutaneous Ventricular Assist Device Support and Patient Management
Discussion: Advanced Surgical Uses of Percutaneous Ventricular Assist Device Support and Patient Management Presentation 1: Impella 5.0/5.5 in the Setting of Post-cardiotomy FailurePresented by: Hermann Reichenspurner, MD, PhDDr Reichenspurner started his presentation by listing the indications of Impella 5.0/5.5 as follows:Cardiogenic shock;Weaning from extracorporeal membrane oxygenation (ECMO);Bridge-to-bridge before left ventricular assist device (LVAD) implantatio... (Source: Radcliffe Cardiology)
Source: Radcliffe Cardiology - February 14, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research