Cardiovascular Involvement in Fabry ’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management

Cardiovascular Involvement in Fabry ’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management Fabry’s disease (FD) is a multisystem X-linked disease caused by pathogenic variants in the galactosidase-α (GLA) gene, leading to reduced α-galactosidase A (α-Gal A) enzyme activity.1 Thi s reduction is responsible for the progressive lysosomal storage of globotriaosylceramide (Gb3) and related globotriaosylsphingosine (lyso-Gb3) in several tissues and orga...
Source: Radcliffe Cardiology - Category: Cardiology Authors: Source Type: research