Making the Most of Innovation in Personalised Medicine: An EU Strategy for a Faster Bench to Bedside and Beyond Process
Personalised medicine promises to revolutionise healthcare, with its key goal of providing the right treatment to the right patient at the right time, and thus the potential of improving quality of life and helping to bring down healthcare costs. However, a major problem with broader implementation of personalised medicine is patient access to new drugs, devices and treatments. The fact that a new medicine or innovative product can sometimes take as long as 20 years to get from bench to bedside is not only clearly undesirable but is arguably unacceptable in the 21st century. This paper looks in detail at the issues surroun...
Source: Public Health Genomics - April 15, 2019 Category: Genetics & Stem Cells Source Type: research
Factors Influencing Not Perceiving Family Health History Assessments as Important: Opportunities to Improve Dissemination of Evidence-Based Population Screening for Cancer
Conclusions: A sizable proportion of the public does not perceive FHH to be very important, may be hard to reach, and impede implementation of population screening guidelines for inherited cancers. Campaigns to increase the perceived value of FHH assessment may need to be tailored to demographic subgroups, emphasize cancer prevention, and encourage family communication.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - April 15, 2019 Category: Genetics & Stem Cells Source Type: research
Genetic Knowledge within a National Australian Sample: Comparisons with Other Diverse Populations
Conclusion: Compared with previous surveys, the current sample showed significantly better genetic knowledge. However, certain areas that relate to public understating still indicate rampant misperceptions.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - February 27, 2019 Category: Genetics & Stem Cells Source Type: research
Challenges and Opportunities for Cancer Predisposition Cascade Screening for Hereditary Breast and Ovarian Cancer and Lynch Syndrome in Switzerland: Findings from an International Workshop
Conclusions: This paper describes the processes and key findings of an international workshop on cancer predisposition cascade screening, which will guide the CASCADE study in Switzerland.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - January 31, 2019 Category: Genetics & Stem Cells Source Type: research
Use and Impact of the 21-Gene Recurrence Score in Relation to the Clinical Risk of Developing Metastases in Early Breast Cancer Patients in the Netherlands
Conclusion: In the Netherlands, the 21-RS test is applied both inside and outside the guideline-directed area. In case of discordance between the genomic and clinical risk, patients were treated in line with the result of the 21-RS.Public Health Genomics 2018;21:1 –8 (Source: Public Health Genomics)
Source: Public Health Genomics - January 16, 2019 Category: Genetics & Stem Cells Source Type: research
Erratum
Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - December 14, 2018 Category: Genetics & Stem Cells Source Type: research
How Online Family History Tool Design and Message Content Impact User Perceptions: An Examination of Family Health < b > < i > Link < /i > < /b >
Conclusion: Our data analysis suggests that certain aspects of the Family HealthLink tool could be executed more effectively to take fuller advantage of opportunities for online personalization.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - December 13, 2018 Category: Genetics & Stem Cells Source Type: research
Developing a Process for Returning Medically Actionable Genomic Variants to Latino Patients in a Federally Qualified Health Center
Conclusion: Efforts to bring precision medicine to community-based health centers serving minority patients may require multilevel engagement activities to include individuals, providers, health systems, and the community.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - December 6, 2018 Category: Genetics & Stem Cells Source Type: research
Current Social Media Conversations about Genetics and Genomics in Health: A Twitter-Based Analysis
Conclusions: This content analysis provides insight about the types of conversation related to genomics and health. Conversations about genomics are occurring on Twitter, and they frequently emphasize rare genetic diseases and genetic disorders. These discussions tend to be driven by key influencers who primarily include news media outlets. Further understanding of the discussions related to genomics and health in social media may offer insight about topics of importance to the public.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - November 22, 2018 Category: Genetics & Stem Cells Source Type: research
Implementation of a Carrier Screening Program in a High-Risk Undergraduate Student Population Using Digital Marketing, Online Education, and Telehealth
Conclusions: Findings suggested that the use of targeted marketing helped promote preconception screening in this population. The study demonstrated that video education was effective in educating participants about benefits and limitations of testing. Also, the use of telehealth technology facilitated access to professional genetic counseling services. This study serves as a model for future public health initiatives.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - November 8, 2018 Category: Genetics & Stem Cells Source Type: research
Factors Associated with Acceptability, Consideration and Intention of Uptake of Direct-To-Consumer Genetic Testing: A Survey Study
Conclusion: Informed decision making may be hampered as individuals with lower how-to knowledge were found to be more interested in pursuing testing. The identified characteristics can be used in development and distribution of public and personalized information, in order to help consumers make a truly informed decision.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2018 Category: Genetics & Stem Cells Source Type: research
Controversies among Cancer Registry Participants, Genomic Researchers, and Institutional Review Boards about Returning Participants ’ Genomic Results
Conclusions: Significant differences emerged between the stakeholder groups in several ROR scenarios. Policies that are acceptable to participants, researchers and IRBs, and that ensure human subject protections and facilitate research are needed.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - September 18, 2018 Category: Genetics & Stem Cells Source Type: research
Title Page
Public Health Genomics 2018;21:I –II (Source: Public Health Genomics)
Source: Public Health Genomics - September 17, 2018 Category: Genetics & Stem Cells Source Type: research
Abstracts from Plenary and Keynote Speakers
Public Health Genomics 2018;21:1 –9 (Source: Public Health Genomics)
Source: Public Health Genomics - September 17, 2018 Category: Genetics & Stem Cells Source Type: research
Submitted Abstracts from Summer School Participants
Public Health Genomics 2018;21:10 –23 (Source: Public Health Genomics)
Source: Public Health Genomics - September 17, 2018 Category: Genetics & Stem Cells Source Type: research
