Antibiotics-Induced Obesity: A Mitochondrial Perspective
Antibiotics are the first line of treatment against infections and have contributed immensely to reduce the morbidity and mortality rates. Recently, extensive use of antibiotics has led to alterations of the gut microbiome, predisposition to various diseases and most importantly, increase in the emergence of antibiotic-resistant bacteria, which poses a major threat to global public health. Another major issue faced worldwide due to unregulated use of antibiotics in children as well as in adults is the influence of metabolism and body weight homeostasis, leading to obesity. Apart from the involvement of biosocial causes inf...
Source: Public Health Genomics - December 14, 2017 Category: Genetics & Stem Cells Source Type: research

Assessment of Direct-to-Consumer Genetic Testing Policy in Korea Based on Consumer Preference
Conclusions: These findings imply that DTC-GT requires an improvement in government policy-making criteria and the implementation of practical measures to guarantee test accuracy and genetic information.Public Health Genomics 2017;20:166-173 (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Cancer Genomic Resources and Present Needs in the Latin American Region
In Latin America (LA), cancer is the second leading cause of death, and little is known about the capacities and needs for the development of research in the field of cancer genomics. In order to evaluate the current capacity for and development of cancer genomics in LA, we collected the available information on genomics, including the number of next-generation sequencing (NGS) platforms, the number of cancer research institutions and research groups, publications in the last 10 years, educational programs, and related national cancer control policies. Currently, there are 221 NGS platforms and 118 research groups in LA de...
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Cancer Genomics and Public Health
Public Health Genomics 2017;20:67-69 (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Pancreas Cancer Precision Treatment Using Avatar Mice from a Bioinformatics Perspective
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related death among solid malignancies. Unfortunately, PDAC lethality has not substantially decreased over the past 20 years. This aggressiveness is related to the genomic complexity and heterogeneity of PDAC, but also to the absence of an effective screening for the detection of early-stage tumors and a lack of efficient therapeutic options. Therefore, there is an urgent need to improve the arsenal of anti-PDAC drugs for an effective treatment of these patients. Patient-derived xenograft (PDX) mouse models represent a promising strategy to personalize PD...
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Prevalence Estimates of Rare Congenital Anomalies by Integrating Two Population-Based Registries in Tuscany, Italy
Conclusions: This study represents an example of integration of registries operating in the field of rare diseases. Providing the accurate prevalence of rare CAs is a key point to improving surveillance, supporting public health policies, and planning healthcare.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Author and Subject Index Vol. 20, No. 2, 2017
Public Health Genomics 2017;20:148 (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Title Page / Table of Contents
Public Health Genomics 2017;20:63-66 (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Providing Personalised Nutrition: Consumers' Trust and Preferences Regarding Sources of Information, Service Providers and Regulators, and Communication Channels
Conclusion: These results may assist in informing local initiatives to encourage acceptance and adoption of country-specific tailored personalised nutrition services, therefore benefiting individual and public health.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Online Education and e-Consent for GeneScreen, a Preventive Genomic Screening Study
Conclusions: The ease of deciding to join a genomic screening study and comprehension of its key features should be treated as different phenomena in research and practice. There is a need for a more nuanced understanding of how individuals respond to web-based consent information.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Genetics and Insurance in Australia: Concerns around a Self-Regulated Industry
Conclusion: Industry self-regulation of the use of genetic information by life insurers, combined with a lack of government oversight, is inappropriate and threatens to impede the progress of genomic medicine in Australia. At this critical time, Australia requires closer government oversight of the use of genetic information in insurance.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - October 25, 2017 Category: Genetics & Stem Cells Source Type: research

Providing Personalised Nutrition: Consumers' Trust and Preferences Regarding Sources of Information, Service Providers and Regulators, and Communication Channels
Conclusion: These results may assist in informing local initiatives to encourage acceptance and adoption of country-specific tailored personalised nutrition services, therefore benefiting individual and public health.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - October 19, 2017 Category: Genetics & Stem Cells Source Type: research

Prevalence Estimates of Rare Congenital Anomalies by Integrating Two Population-Based Registries in Tuscany, Italy
Conclusions: This study represents an example of integration of registries operating in the field of rare diseases. Providing the accurate prevalence of rare CAs is a key point to improving surveillance, supporting public health policies, and planning healthcare.Public Health Genomics (Source: Public Health Genomics)
Source: Public Health Genomics - October 18, 2017 Category: Genetics & Stem Cells Source Type: research

Author and Subject Index Vol. 20, No. 2, 2017
Public Health Genomics 2017;20:148 (Source: Public Health Genomics)
Source: Public Health Genomics - September 19, 2017 Category: Genetics & Stem Cells Source Type: research

Title Page / Table of Contents
Public Health Genomics 2017;20:63-66 (Source: Public Health Genomics)
Source: Public Health Genomics - September 19, 2017 Category: Genetics & Stem Cells Source Type: research