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An association between niacin skin flush response and plasma triglyceride levels in patients with schizophrenia
Phospholipase A2 (PLA2) activation triggers the release of arachidonic acid (20:4n-6, ARA) from membrane phospholipids, and this mechanism is reportedly involved in a variety of physiological processes, including dopaminergic neurotransmission, insulin secretion and the skin flush response to the water-soluble B vitamin niacin [1-6]. Individuals with schizophrenia frequently exhibit abnormal signaling of dopamine and other neurotransmitters, disturbances of lipid and glucose metabolism and attenuated niacin-induced skin flushing [1,4,5,7-9]. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - February 20, 2020 Category: Biomedical Science Authors: Sergej Nadalin, Suzana Jonovska, Vesna Šendula Jengić, Alena Buretić-Tomljanović Tags: Original research article Source Type: research
Editorial Board
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Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 31, 2020 Category: Biomedical Science Source Type: research
Publisher's Note
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Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 31, 2020 Category: Biomedical Science Source Type: research
Influence of clinical characteristics on maternal DHA and other polyunsaturated fatty acid status in pregnancy: A systematic review
The important roles of omega-3 long-chain polyunsaturated fatty acids (LCPUFA) in maternal and infant health have been the subject of considerable research [1-4]. The omega-3 LCPUFA, in particular docosahexaenoic acid (DHA) (22:6n-3), are critical in supporting the development of the brain and central nervous system of a fetus [5-7]. There is also evidence to support the importance of achieving adequate maternal DHA intakes during pregnancy to reduce the incidence of preterm birth [8]. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 28, 2020 Category: Biomedical Science Authors: N.A. Wilson, E. Mantzioris, P.F. Middleton, B.S. Muhlhausler Source Type: research
A single meal has the potential to alter brain oxylipin content
low-fat/low-sucrose diet (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 28, 2020 Category: Biomedical Science Authors: J.E. Norman, H.H. Aung, Y. Otoki, Z. Zhang, A.Y. Taha, J.C. Rutledge Source Type: research