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FACS 2019: Fatty Acid Metabolism and Oxidation
Writing in early 2021, the 14th Fatty Acids and Cell Signaling workshop held Sept/Oct 2019 in Austin, Texas, USA seems a long long time ago in a place far far away. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - March 15, 2021 Category: Biomedical Science Authors: J. Thomas Brenna, Ameer Y. Taha Source Type: research

Comparison of human and rodent cell models to study myocardial lipid-induced insulin resistance
The enduring availability of sufficient chemical energy, in the form of ATP, is vital for proper cardiac function. Energy is needed not only for rhythmic contraction of the cardiomyocytes but also for ion homeostasis, and for the functioning of enzymes, proteins and organelles involved in the selection, uptake, and utilization of fuels used to produce ATP. The energy needs of the heart cannot be overestimated as, for instance, the human heart is responsible for approximately 10% of whole-body fuel consumption [1]. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - March 12, 2021 Category: Biomedical Science Authors: Li-yen Wong, Jan F.C. Glatz, Shujin Wang, Ilvy M.E. Geraets, Sabina Vanherle, Arthur van den Wijngaard, Han Brunner, Joost J.F.P. Luiken, Miranda Nabben Tags: Original research article Source Type: research

Comparison of human and rodent cell models to study myocardial lipid-induced insulin resistance.
The enduring availability of sufficient chemical energy, in the form of ATP, is vital for proper cardiac function. Energy is needed not only for rhythmic contraction of the cardiomyocytes but also for ion homeostasis, and for the functioning of enzymes, proteins and organelles involved in the selection, uptake, and utilization of fuels used to produce ATP. The energy needs of the heart cannot be overestimated as, for instance, the human heart is responsible for approximately 10% of whole-body fuel consumption [1]. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - March 12, 2021 Category: Biomedical Science Authors: Li-yen Wong, Jan F.C. Glatz, Shujin Wang, Ilvy M.E. Geraets, Sabina Vanherle, Arthur van den Wijngaard, Han Brunner, Joost J.F.P. Luiken, Miranda Nabben Source Type: research

Editorial Board
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Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - March 1, 2021 Category: Biomedical Science Source Type: research

Polymorphisms rs2745557 in PTGS2 and rs2075797 in PTGER2 are associated with the risk of chronic obstructive pulmonary disease development in a Tunisian cohort
COPD (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 28, 2021 Category: Biomedical Science Authors: Salma MANI, Xavier Norel, Mathilde Varret, Sarra Bchir, Amel ben Anes, Abdelahamid Garrouch, Zouhair Tabka, Dan Longrois, Karim Chahed Source Type: research

Plasma oxylipin levels associated with preterm birth in preterm labor ✰
Preterm labor is a common clinical problem in obstetrics. Since the majority of women with preterm labor eventually deliver at full term, biomarkers are needed to more accurately predict who will deliver preterm. Oxylipins, given their importance in inflammation regulation, are highly interesting in this respect since labor is an inflammatory process. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 23, 2021 Category: Biomedical Science Authors: M. Svenvik, J. Raffetseder, L. Brudin, R. Lindberg, M. Blomberg, D. Axelsson, M.C. Jenmalm, J. Ernerudh, M.L. Nording Tags: Original research article Source Type: research

Plasma oxylipin levels associated with preterm birth in preterm labor
Preterm labor is a common clinical problem in obstetrics. Since the majority of women with preterm labor eventually deliver at full term, biomarkers are needed to more accurately predict who will deliver preterm. Oxylipins, given their importance in inflammation regulation, are highly interesting in this respect since labor is an inflammatory process. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 23, 2021 Category: Biomedical Science Authors: M. Svenvik, J. Raffetseder, L. Brudin, R. Lindberg, M. Blomberg, D. Axelsson, M.C. Jenmalm, J. Ernerudh, M.L. Nording Source Type: research

Blood omega-3 fatty acids and death from COVID-19: A Pilot Study
COVID-19, the illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been diagnosed in over 80 million people worldwide as of the end of 2020, and over 1.8 million have died [1]. Although 81% of symptomatic individuals have relatively mild disease, 14% will develop severe disease characterized by dyspnea, hypoxia, or>50 percent lung involvement by imaging, with the remaining 5% developing critical disease characterized by respiratory failure, shock, and/or multiorgan dysfunction [2]. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 20, 2021 Category: Biomedical Science Authors: Arash Asher, Nathan L. Tintle, Michael Myers, Laura Lockshon, Heribert Bacareza, William S. Harris Source Type: research

Polyunsaturated fatty acids as predictors of future suicide attempt
Every year, almost 800,000 people die by suicide, and 10 to 20 times more individuals attempt suicide, indicating that both suicide and non-fatal suicidal behaviors are prevalent problems that need to be addressed [1]. More than two-thirds of suicide decedents die on the first attempt [2], suggesting a need for early detection and prevention of suicide attempts. The study of suicidal behaviors is highly relevant to the reduction of suicide mortality since a history of suicide attempt confers a 42-fold increased risk for suicide [3]. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 11, 2021 Category: Biomedical Science Authors: Federico M. DARAY, Leandro N. GRENDAS, Demi án E. RODANTE, Andrea E. ERRASTI, Gabriel G. CASES, Claudio F. MOIX, Raúl E. UICICH, María I. GIMÉNEZ, Soledad PUPPO, Gerardo H. FASOLINO, Alicia PORTELA, Hanga C. GALFALVY, M. Elizabeth SUBLETTE Source Type: research

Baseline Red Blood Cell and Breast Milk DHA Levels Affect Responses to Standard Dose of DHA in Lactating Women on a Controlled Feeding Diet
The importance of the omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) in human development is well-documented [1-3]. Both the brain and retina are exceptionally rich in DHA, where it is an integral part of their respective tissue structures. As such, a significant amount of DHA is provided to the fetus/infant from the third trimester through the first 18 months of life via several mechanisms [4]. While there is evidence that the fetus can elongate precursor fatty acids to make DHA [5], the amount of DHA available to the fetus is primarily determined by the amount in maternal circulation during pregnancy and t...
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 11, 2021 Category: Biomedical Science Authors: Kristina H. Jackson, Kevin C. Klatt, Marie A. Caudill, Melissa Q. McDougall, Allyson A. West, Cydne A. Perry, Olga V. Malysheva, William S. Harris Source Type: research

Effect of n-3 polyunsaturated fatty acid supplementation on muscle mass and function with aging: a meta-analysis of randomized controlled trials
The gradual loss of age-related muscle mass and muscle function are responsible for the impairment of quality of life and activity in the elderly [1]. With the improvement of the methodology and technology for measuring body composition and health status of the elderly, scientific communities give increasing attention to muscle mass and muscle function [2]. It has been reported that about 10% of muscles have disappeared at the age of 50, and muscle function will decline by 12% - 14% every ten years from the age of 50. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 11, 2021 Category: Biomedical Science Authors: Wen-jun Ma, Hui Li, Wei Zhang, Jie Zhai, Jun Li, He Liu, Xiao-fei Guo, Duo Li Source Type: research

Dietary Fat Content and Adipose Triglyceride Lipase and Hormone-Sensitive Lipase Gene Expressions in Adults ’ Subcutaneous and Visceral Fat Tissues
Adipose triglyceride lipase (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 7, 2021 Category: Biomedical Science Authors: Rahim Zareie, Emad Yuzbashian, Hamed Rahimi, Golaleh Asghari, Maryam Zarkesh, Mehdi Hedayati, Abolghassem Djazayery, Ariyo Movahedi, Parvin Mirmiran, Alireza Khalaj Source Type: research

Editorial Board
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Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - January 1, 2021 Category: Biomedical Science Source Type: research

Effects of uric acid on oxidative and nitrosative stress and other related parameters in SH-SY5Y human neuroblastoma cells.
Uric acid (UA) is the end -product of purine catabolism in humans and higher primates and comprises about 65% of the total antioxidant capacity of plasma [1]. Urate circulates in humans at concentrations that are near its limit of solubility and many times higher than those in most other mammals. In patients with ischemic stroke, the most common type of stroke which is a leading cause of disability and the second most common cause of dementia, UA reduces the incidence of early clinical deterioration and improves outcomes compared to placebo [2]. (Source: Prostaglandins, Leukotrienes and Essential Fatty Acids)
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - December 30, 2020 Category: Biomedical Science Authors: Frederic M ármol, Juan Sanchez, Albert Martínez-Pinteño Source Type: research