Toxicity of resin-matrix cements in contact with fibroblast or mesenchymal cells
AbstractThe main aim of this study was to perform an integrative review on the toxic effects of resin-matrix cements and their products in contact with fibroblasts or mesenchymal cells. A bibliographic search was performed on PubMed using the following search terms: “cytotoxicity” AND “fibroblast” OR “epithelial” OR “mesenchymal” AND “polymerization” OR “degree of conversion” OR “methacrylate” OR “monomer” AND “resin cement” OR “resin-based cement”. The initial search in the available database yielded a total of 277 articles of which 21 articles were included in this review. A decr...
Source: Odontology - November 12, 2022 Category: Dentistry Source Type: research
Skeletal and soft-tissue changes in humans with untreated normal occlusion throughout lifetime: a systematic review
AbstractAge-related skeletal and soft-tissue changes are important in orthodontics, especially due to the increase of adult patients seeking treatment. The aim of this study is to assess the available evidence regarding age-related skeletal and soft-tissue changes in untreated Angle Class I. Articles studying skeletal and soft-tissue changes in orthodontically untreated subjects with Angle Class I and comparing them between age groups were included. Studies focusing on a single age group or in languages other than English were excluded. Risk of bias was assessed with both the MINORS and ROBINS-I tools. 50 studies were incl...
Source: Odontology - November 9, 2022 Category: Dentistry Source Type: research
Effects of hydroxyapatite nanorods prepared through Elaeagnus Angustifolia extract on modulating immunomodulatory/dentin –pulp regeneration genes in DPSCs
This study determined the impacts of nano-hydroxyapatite (nHA) prepared throughElaeagnus Angustifolia extract (EAE) to enhance the relative expression of immunomodulatory/dentin –pulp regeneration genes in DPSCs. To produce nHA and modified nHA via EAE (nHAEA), the sol–gel technique was used. The functional groups of nanoparticles (NPs), morphological, and optical features were determined using Fourier transform infrared (FTIR), X-ray diffraction (XRD), Scanning electro n microscopy (SEM) together with energy-dispersive X-ray analysis (EDAX), and Transmission electron microscopy (TEM). The cell viability was then deter...
Source: Odontology - November 9, 2022 Category: Dentistry Source Type: research
Streptococcus anginosus: a stealthy villain in deep odontogenic abscesses
AbstractOdontogenic infections (OIs) occasionally spread to deep facial and neck tissues. Our study aimed to explore the role ofStreptococcus anginous group (SAG) in these severe OIs. A retrospective study of patients aged ≥ 18 years who required hospital care for acute OI was conducted. We analysed data of OI microbial samples and recorded findings of SAG and other pathogens. These findings were compared with data regarding patients’ prehospital status and variables of infection severity. In total, 290 pati ents were included in the analyses. The most common (49%) bacterial finding was SAG. Other common findings...
Source: Odontology - November 8, 2022 Category: Dentistry Source Type: research
MicroRNA and their implications in dental pulp inflammation: current trends and future perspectives
AbstractMicroRNAs (miRNAs) are short, 19 –23 nucleotide non-coding RNA molecules that regulate gene expression by silencing or degrading the target mRNA gene. Since their discovery in the nineties of the last century, they have emerged as key inflammatory regulators. Inflammation induces the synthesis of various miRNAs that modulate the expression of multiple molecules involved in orchestrating the inflammatory response. This review aims to provide an insight into the role of miRNAs as potential biomarkers, mediators, and potential therapeutic targets of dental pulp inflammation. A literature search was conducted using t...
Source: Odontology - October 30, 2022 Category: Dentistry Source Type: research
Diode laser versus sclerotherapy: bloodless approaches in the treatment of oral pyogenic granuloma (randomised controlled clinical trial)
In conclusion, diode laser treatment of P G is a reliable, less invasive, and sensitive procedure that requires an experienced operator and specialised equipment. However, ethanolamine oleate sclerotherapy is an inexpensive, simple technique besides being less prone to recurrence problems, especially when treatment duration is not a concern . (Source: Odontology)
Source: Odontology - October 28, 2022 Category: Dentistry Source Type: research
Force exerted on maxillary anterior teeth in mandibular unilateral and bilateral distal extension partial edentulous situation
AbstractThe purpose of this study was to determine the influence of mandibular unilateral and bilateral distal extension partial edentulous situation and the use of removable partial dental prostheses on the force exerted on maxillary anterior teeth. A commercially available jaw model with exchangeable teeth was used. Seven experimental conditions of mandibular distal extension edentulous situation were prepared and a distal extension removable partial dental prosthesis to replace missing posterior teeth was fabricated. The occlusal force was measured by inserting an occlusal force measuring film between the maxillary and ...
Source: Odontology - October 28, 2022 Category: Dentistry Source Type: research
Differences in periodontal parameters between SPT patients who regularly and irregularly visited the dental clinic analyzed at tooth level: a 14-year retrospective cohort study
This study showed that lack of routine in attending the SPT program significantly decreased the periodontal parameters, thus highlighting the importance of cont inuing with the program to maintain the periodontal health. (Source: Odontology)
Source: Odontology - October 25, 2022 Category: Dentistry Source Type: research
Usefulness of preoperative computed tomography findings for airway management in patients with acute odontogenic infection: a retrospective study
This study was performed to determine the most important imaging findings indicating preoperative selection of an appropriate intubation method. This retrospective study included 113 patients who underwent anti-inflammatory treatment for odontogenic infection. The patients were divided into two groups according to the intubation method: a Macintosh laryngoscope (45 patients) and others (video laryngoscope and fiberscope) (68 patients). The extent of inflammation in each causative tooth, the severity of inflammation (S1 –4), and their influence on the airway were evaluated by computed tomography. The causative teeth were ...
Source: Odontology - October 24, 2022 Category: Dentistry Source Type: research
Enhanced effectiveness of silver diamine fluoride application with light curing on natural dentin carious lesions: an in vitro study
In conclusion, shortened application time with light curing enhanced SDF reminer alization similarly to the conventional method. (Source: Odontology)
Source: Odontology - October 21, 2022 Category: Dentistry Source Type: research
Update on citric acid use in endodontic treatment: a systematic review
AbstractThis systematic review aims to analyse the available evidence concerning the use of citric acid (CA) in endodontics treatment and to assess its results in terms of different considerations: effect on smear layer removal, influence on sealer bond strength, activation effect by means of sonic or ultrasonic devices, effects on dentine surface, antibacterial activity, and effectiveness boost for regenerative procedures, releasing growth factors from dentin. To evaluate the results of CA as a final irrigant and compare them to other chelating agents. This review followed the PRISMA checklist. An electronic search was co...
Source: Odontology - October 11, 2022 Category: Dentistry Source Type: research
Effects of nicotine and lipopolysaccharide stimulation on adhesion molecules in human gingival endothelial cells
AbstractSmoking is a risk factor for periodontitis, and the immune response of periodontal tissues in patients with periodontitis may be strongly affected by smoking. The purpose of this study was to elucidate the bioactivity and signal transduction of human gingival endothelial cells (HGECs) due to nicotinic stimulation using a cultured medium supplemented with lipopolysaccharide (LPS) as a model of periodontitis. HGECs were cultured in medium supplemented with LPS, nicotine, nicotine + LPS, and medium supplemented without nicotine or LPS (control). Cell proliferation was assessed using Alamar blue. Cytotoxicity was ...
Source: Odontology - October 10, 2022 Category: Dentistry Source Type: research
Antibacterial effect, cytotoxicity, and bond strength of a modified dental adhesive containing silver nanoparticles
In conclusion, incorporating 500 or 1000 ppm of NAg into an etch-and-rinse adhesive system led to an antibacterial effect without altering the cytotoxicity. SBMP at 500 ppm presented a higher μTBS at 1 year. (Source: Odontology)
Source: Odontology - October 8, 2022 Category: Dentistry Source Type: research
Temperature changes and hardness of resin-based composites light-cured with laser diode or light-emitting diode curing lights
AbstractThe temperature and Vickers Hardness (VH) at the top and bottom surfaces of three resin-based composites (RBCs) were measured when light-cured using five light-curing units (LCUs). The spectrum, power, and energy delivered to the top of the RBCs and transmitted through the RBCs were measured. Starting at 32 ℃, the temperature rise produced by the Monet Laser (ML—1 s and 3 s), Valo Grand (VG—3 s and 10 s), DeepCure (DC—10 s), PowerCure, (PC—3 s and 10 s) and PinkWave (PW—10 s) were measured at the bottom of specimens 2 mm deep × 6 mm wide made of Filtek Universal A2, Tetric Ev oceram A2 an...
Source: Odontology - October 3, 2022 Category: Dentistry Source Type: research
Intrauterine exposure to omeprazole increases the risk of teeth morphological anomalies in the offspring of a murine model
In this study, we addressed this gap in a murine model. Pregnant female Swiss mice were exposed to daily doses of 40 mg/kg of omeprazole from the 5th to the 17th day of pregnancy and the effects of such exposure on offspring odontogenesis parameters such as morphological abnormalities, disruptions in the ameloblast and odontoblast layers and the presence of dentin matrix were measured. Omeprazole exposure significantly increased the prevalence (control: 21.6%; treatment: 60%; p = 0.001) and the risk (posterior mean and 95% credible interval; control: 0.230 [0.129; 0.347]; treatment: 0.593 [0.449; 0.730]) of offsprin...
Source: Odontology - October 1, 2022 Category: Dentistry Source Type: research
