Explaining the colour of natural healthy gingiva
AbstractTo examine the differences between natural gingival colour in men and women. To determine the degree of predictability of changes in the gingival colour coordinates recorded for healthy gingiva, according to age, long-term medication, frequency of toothbrushing, and smoking habits. The CIELAB colour coordinates were recorded using a spectrophotometer for 360 Caucasian adult participants (aged 18 –92 years), in three zones of the healthy attached gingiva of the maxillary central incisor. Regression models were created for each zone and each sex, taking the L*, a* and b* coordinates as dependent variables and age,...
Source: Odontology - February 25, 2024 Category: Dentistry Source Type: research
Clinical evaluation of posterior flowable short fiber-reinforced composite restorations without proximal surface coverage
AbstractThe purpose of this clinical trail was to assess the clinical behavior of posterior composite restorations supported by a substantial foundation of flowable short fiber-reinforced composite SFRC (everX Flow, GC, Japan) used without proximal surface coverage with particulate filler resin composite (PFC). Seventy patients (20 males, 50 females; mean age: 30 ± 10 years) were randomly enrolled in this trial. Patients received direct restorations of either SFRC covered only on the occlusal surface (1–2 mm) by conventional PFC composite (G-ænial Posterior, GC), or plain conventional PFC composite without fiber...
Source: Odontology - February 23, 2024 Category: Dentistry Source Type: research
Inhibition of DCUN1D1 attenuates periodontitis by suppressing NF- κB signaling
AbstractNuclear factor kappa-B (NF- κB) signaling-mediated inflammation contributes greatly to the pathogenesis of periodontitis. Neddylation, a ubiquitin-like posttranslational modification, is known to regulate NF-κB signaling. DCUN1D1 (defective in cullin neddylation 1 domain containing 1) is a critical factor in neddylation and has been shown to regulate NF-κB activation. However, the previse roles of DCUN1D1 in periodontitis are not fully elucidated. To explore the roles of DCUN1D1 in periodontitis, the expression of DCUN1D1 was measured in gingival tissues of patients with periodontitis. We inhibited DCUN1D1 by si...
Source: Odontology - February 23, 2024 Category: Dentistry Source Type: research
The use of sonic and ultrasonic activation of endodontic sealer to improve sealer filling quality in the root canal: a scoping review
AbstractThis scoping review aimed to map whether the use of sonic and ultrasonic methods to activate the endodontic sealer improves the sealer filling quality in the root canal, considering the bond strength and intratubular penetration to the root dentin as evaluation criteria. The study protocol was prospectively registered and is available online (https://osf.io/x5fma/). Reporting was based on PRISMA Extension for Scoping Reviews. The search was performed in Embase, PubMed, Scopus, and Web of Science. We selected studies without time and language restrictions that used sonic or ultrasonic methods to activate endodontic ...
Source: Odontology - February 21, 2024 Category: Dentistry Source Type: research
Cutting efficiency and corrosion resistance of heat-treated endodontic files after various disinfection protocols
AbstractThe aim of this study is to evaluate the effect of various disinfection protocols on the cutting efficiency and chemical composition of ProTaper, Twisted File, Twisted File Adaptive, and Hedstr öm files. Four experimental groups (n = 10) were presoaked in either enzymatic solution or 1% sodium hypochlorite for 30 min, followed by either 5 or 15 min of ultrasonic cleaning and then autoclaved. Resin-simulated canals with a single curvature of 38–40° were prepared by each instrument system. Cutting efficiency of each instru ment was analyzed by subtracting the final weight from the initial weight of the res...
Source: Odontology - February 21, 2024 Category: Dentistry Source Type: research
lncRNA TMEM161B-AS1 screened the onset of oral squamous cell carcinoma in HPV-infected patients, predicted poor prognosis, and regulated cell progression via modulating the miR-651-5p/BDNF axis
This study evaluated the significance and mechanism of TMEM161B-AS1 and miR-651-5p in HPV-OSCC aiming to provide novel insight into the mechanism of HPV-OSCC development. Expression of TMEM161B-AS1 and miR-561-5p was analyzed in healthy individuals, HPV-infected non-OSCC patients, and HPV-OSCC patients using PCR. Their significance in HPV-OSCC occurrence and prognosis was evaluated by logistic regression, ROC, Kaplan–Meier, and Cox regression analysis. In OSCC cells, CCK8 and Transwell assays were employed for assessing cell growth and metastasis. The luciferase reporter assay and cell transfection were performed to eval...
Source: Odontology - February 20, 2024 Category: Dentistry Source Type: research
Influence of bioceramic sealers on dentinal tubule penetration and antimicrobial effectiveness: a systematic review and meta-analysis of in vitro studies
AbstractThe aim of this systematic review and meta-analysis (SRM) was to evaluate whether bioceramic sealers have better penetration capacity in dentinal tubules and antimicrobial activity when compared to AH Plus ® sealer. This SRM was recorded in the Open Science Framework database and followed the guidelines of the PRISMA 2020. Five databases were searched by two independent reviewers. Only in vitro studies that evaluated the effects of bioceramic sealers on dentinal tubule penetration and antimicrobial a ctivity outcomes compared to AH Plus® sealer were included. Meta-analysis was conducted using R software, using th...
Source: Odontology - February 19, 2024 Category: Dentistry Source Type: research
Evaluation of tooth color change after a bleaching process with different lasers
AbstractThe aim of this in vitro study was to evaluate the efficiency of diode laser-activated bleaching systems for color change of teeth. 75 extracted teeth were studied in five different bleaching protocols. Group 1: diode laser 445 nm, 320 µm fiber, 0.5W, continuous wave mode,dose 53 J/cm2. Group 2: diode laser 970 nm, 320 µm fiber, 1W, continuous wave mode, dose 106.10 J/cm2. Group 3: diode laser 940 nm, bleaching handpiece, 7W, continuous wave mode,dose 105 J/cm2. Group 4: diode laser 940 nm, 300 µm fiber, 2W, continuous wave mode, dose47.16 J/cm2. Group 5: bleaching process without laser activa...
Source: Odontology - February 17, 2024 Category: Dentistry Source Type: research
Application of mesenchymal stromal cell sheets to prevent medication-related osteonecrosis of the jaw with titanium implants in rats
This study aimed to investigate a rat model of MRONJ induced by extraoral placement of titanium materials and the use of mesenchymal stromal cell (MSCs) sheets to prevent MRONJ. Eight-week-old male rats were administered zoledronate and dexamethasone thrice weekly until killing. A week after drug initiation, a titanium screw and a plate were placed on the left buccal side of the mandible. Allogeneic bone marrow-derived MSC sheets were co-grafted with the titanium plates in the MSC sheet ( +) group. Six weeks after titanium placement, the rats were killed, and their excised mandibular bones were subjected to micro-comput...
Source: Odontology - February 17, 2024 Category: Dentistry Source Type: research
Prevalence of multiple roots and complex canal morphology in mandibular premolars among a selected Southern Egyptian sub-population: a CBCT-analysis
This study investigated the prevalence of multiple roots and complex canal morphology of mandibular premolars in a selected Egyptian sub-population using cone beam computed tomography (CBCT). 283 CBCT scans (131 males, 152 females, age 18 –70) included 1132 mandibular premolars (566 first, and 566 second premolars) were viewed for incidences ofvariation in root numbers and canal configuration according to Vertucci’s classification. CBCT images were assessed by two endodontists, data were statistically analyzed using Fisher exact and Chi-square tests. The majority of first premolars (85.7%) exhibited a single root, wher...
Source: Odontology - February 13, 2024 Category: Dentistry Source Type: research
Prevalence of mandibular premolars among a selected multiple roots and complex canal morphology in Southern Egyptian sub-population: a CBCT-analysis
This study investigated the prevalence of multiple roots and complex canal morphology of mandibular premolars in a selected Egyptian sub-population using cone beam computed tomography (CBCT). 283 CBCT scans (131 males, 152 females, age 18 –70) included 1132 mandibular premolars (566 first, and 566 second premolars) were viewed for incidences ofvariation in root numbers and canal configuration according to Vertucci’s classification. CBCT images were assessed by two endodontists, data were statistically analyzed using Fisher exact and Chi-square tests. The majority of first premolars (85.7%) exhibited a single root, wher...
Source: Odontology - February 13, 2024 Category: Dentistry Source Type: research
Relationship between soft tissue dimensions and tomographic radial root position classification system for immediate implant installation
AbstractThe aim of this study was to evaluate the relationship between soft tissue dimensions and radial root position (RRP) classification for immediate implant placement on maxillary anterior teeth. Maxillary anterior teeth (n = 420) were analyzed in the radial plane of cone beam computed tomography (CBCT) scans. Each tooth was classified according to its RRP: class I, (IA, IB); class II (IIA, IIB) class III; class IV, and class V. Soft tissue thickness at different landmarks, supracrestal soft tissue height, and cre stal bone thickness were measured in CBCT. Keratinized tissue width was clinically measured. Gingival...
Source: Odontology - February 7, 2024 Category: Dentistry Source Type: research
Correlation of salivary cytokine IL-17A and 1,25 dihydroxycholecalciferol in patients undergoing orthodontic treatment
AbstractThe management of malocclusion has developed greatly in terms of treatment simulation and biomechanics, but treatment duration has been a great concern to the clinician as well as the patient. 1-25dihydroxycholecalciferol (biologically active form of Vitamin D) stimulates both osteoclasts and osteoblasts and was found to be the most significant in Orthodontic Tooth Movement acceleration. Inflammatory cytokines like IL-17A also play an important role in osteoclastogenesis and can enhance the rate of Orthodontic Tooth Movement.To perform a simultaneous evaluation of pro-inflammatory salivary cytokine IL-17A and saliv...
Source: Odontology - February 6, 2024 Category: Dentistry Source Type: research
Cerebral activation caused by dental sounds: a functional magnetic resonance imaging study
This study aimed to use functional magnetic resonance imaging (fMRI) to assess the relationship between dental fear and auditory stimuli. Thirty-four right-handed individuals (21 women and 13 men; average age, 31.2 years) were selected. The level of dental fear was assessed using the dental fear survey (DFS). Based on a threshold DFS score > 52, participants were categorized into two groups: dental fear (DF) group (n = 12) and control group (n = 22). Two types of stimuli were presented in a single session: dental and neutral sounds. Cerebral activation during the presentation of these sounds was evaluated...
Source: Odontology - February 3, 2024 Category: Dentistry Source Type: research
Physicochemical and mechanical properties of preheated composite resins for luting ceramic laminates
This study analyzed and compared the physicochemical and mechanical properties of preheated resin composite with light-cured resin cement for luting indirect restorations. 210 specimens of resin cement/resin composite were prepared according to preheating treatment heated (Htd) or not (NHtd). Light-cured resin cement (Variolink Veneer, Ivoclar), and resin composite (Microhybrid —Z100, 3 M; Nanohybrid—Empress direct, Ivoclar; and Bulk fill–Filtek One, 3 M) were used (n = 10). Resin cement specimens were not preheated. The response variables were (n = 10): film thickness, microhardness, liquid sorption and so...
Source: Odontology - February 2, 2024 Category: Dentistry Source Type: research
