The effect of different kinematics on apical debris extrusion with a single-file system
AbstractTo compare the amount of extruded debris caused by different motions using a single-file system. Fifty mandibular first molar teeth were randomized into 5 groups (n = 10) according to the motion tested: Optimize Torque Reverse (OTR), TF Adaptive Motion (TFA), continuous rotation (CR), reciprocation motion (+ 150°, −30°) (REC), and Jeni motion (Jeni). One Curve single file 25/06 (Micro-Mega, Besançon, France) was used in all experimental groups. The root canals were irrigated with 2.5% NaOCl, and the extruded debris were collected at pre-weighted glass vials. The glass vials were kept inside an incubator ...
Source: Odontology - March 14, 2023 Category: Dentistry Source Type: research
TiO2 nanotube-based nanotechnology applied to high-viscosity conventional glass-ionomer cement: ultrastructural analyses and physicochemical characterization
This study characterized TiO2 nanotube (TiO2-nt) ultrastructure and morphology, and the physicochemical impact on high-viscosity conventional glass-ionomer cement (GIC). TiO2-nt was synthesized by the alkaline method (n = 3), assessed by scanning (SEM) and transmission electron microscope (TEM), and was added (3%, 5%, 7%—in weight) to KM (Ketac Molar EasyMix™). Analyses included: SEM; Energy-dispersive spectroscopy (EDS); Raman spectroscopy (RAMAN); Setting time with Gillmore needles (ST); Color (Co); Radi opacity (XR); Water sorption (WS); and solubility (SO). Quantitative data were submitted to ANOVA and Tukey’...
Source: Odontology - March 14, 2023 Category: Dentistry Source Type: research
Macrophages immunomodulation induced by Porphyromonas gingivalis and oral antimicrobial peptides
This study aimed to analyze the immunopathological role of macrophages activated by P. gingivalis in periodontitis and suggested using antimicrobial peptides as therapeutic agents to treat the disease. (Source: Odontology)
Source: Odontology - March 10, 2023 Category: Dentistry Source Type: research
NAT10 promotes osteogenic differentiation of periodontal ligament stem cells by regulating VEGFA-mediated PI3K/AKT signaling pathway through ac4C modification
AbstractPeriodontal tissue regeneration engineering based on human periodontal ligament stem cells (hPDLSCs) provides a broad prospect for the treatment of periodontal disease. N-Acetyltransferase 10 (NAT10)-catalyzed non-histone acetylation is widely involved in physiological or pathophysiological processes. However, its function in hPDLSCs is still missing. hPDLSCs were isolated, purified, and cultured from extracted teeth. Surface markers were detected by flow cytometry. Osteogenic, adipogenic, and chondrogenic differentiation potential was detected by alizarin red staining (ARS), oil red O staining, and Alcian blue sta...
Source: Odontology - March 6, 2023 Category: Dentistry Source Type: research
Physicochemical, mechanical and biological properties of nano-calcium silicate-based cements: a systematic review
In conclusion, the evidence available for the properties of CSC particles in the nano-range is deficient —such properties could be a result of additives which may have enhanced the properties of the material. (Source: Odontology)
Source: Odontology - March 3, 2023 Category: Dentistry Source Type: research
Association between periodontal diseases and COVID-19 infection: a case –control study with a longitudinal arm
AbstractSome studies have suggested potential relationships between periodontal disease and COVID-19, explained by many possible pathological pathways. The aim of this case –control study with a longitudinal arm was to investigate this association. 80 systemically healthy individuals (apart from COVID-19) were involved in this study, divided into 40 patients who had recently had COVID-19 (test, divided into severe and mild/moderate cases) and 40 who had not had COVID -19 (control). Clinical periodontal parameters and laboratory data were recorded. Mann–WhitneyU test, Wilcoxon test, and chi-square test were performed to...
Source: Odontology - March 3, 2023 Category: Dentistry Source Type: research
Speed-sintering and the mechanical properties of 3 –5 mol% Y2O3-stabilized zirconias
AbstractEver faster workflows for the fabrication of all-ceramic restorations are of high economic interest. For that purpose, sintering protocols have been optimized for use in modern sintering furnaces, the so-called speed-sintering. However, conventional furnaces are still the most widely used equipment to sinter zirconia restorations. In this in-vitro study, we evaluated the feasibility of a speed-sintering protocol using a conventional sintering furnace to sinter different dental zirconias (stabilized with 3 mol% up to 5.4 mol% Y2O3) in comparison to a conventional sintering program. The properties evaluated were Y...
Source: Odontology - March 2, 2023 Category: Dentistry Source Type: research
Vertical ridge augmentation of atrophic posterior mandible with corticocancellous onlay symphysis graft versus sandwich technique: clinical and radiographic analysis
AbstractAlveolar ridge augmentation of atrophic posterior mandibular ridge represents a challenge in oral and maxillofacial surgery to restore aesthetic and function. The aim of the study was to compare the clinical and radiographic outcomes of bone formation in atrophic posterior mandibles augmented using onlay symphysis cortico-cancellous bone block with that augmented using sandwich bone augmentation technique (Inlay). Twelve patients were selected with missing mandibular posterior teeth. CBCT were done for all patients preoperatively to assess the residual bone height, ranged between 5 and 7 mm from the inferior alve...
Source: Odontology - February 28, 2023 Category: Dentistry Source Type: research
The relationship of tooth crown dimensions between first molar and central incisor in maxilla
AbstractThe purpose of this study was to investigate a correlation between the cusp dimensions of the first molar and mesiodistal crown diameters of the central incisors in the maxilla. The study materials were composed of dental casts from 29 modern Japanese female subjects with a mean age of 20 years and 8 months. The mesiodistal crown diameters of the maxillary central incisors were measured. The mesiodistal and bucco-lingual crown diameters and the cusp diameters of the maxillary first molars, such as the paracone, metacone, protocone, and hypocone, were also measured. The crown areas and indices of the first molars...
Source: Odontology - February 27, 2023 Category: Dentistry Source Type: research
Effect of resin composite shade on digital fiber-optic transillumination imaging in vitro
In conclusion, DIFOTI images of RCs with high optical translucency resembled those of the natural tooth structure. (Source: Odontology)
Source: Odontology - February 16, 2023 Category: Dentistry Source Type: research
Establishing protein expression profiles involved in tooth development using a proteomic approach
AbstractVarious growth and transcription factors are involved in tooth development and developmental abnormalities; however, the protein dynamics do not always match the mRNA expression level. Using a proteomic approach, this study comprehensively analyzed protein expression in epithelial and mesenchymal tissues of the tooth germ during development. First molar tooth germs from embryonic day 14 and 16 Crlj:CD1 (ICR) mouse embryos were collected and separated into epithelial and mesenchymal tissues by laser microdissection. Mass spectrometry of the resulting proteins was carried out, and three types of highly expressed prot...
Source: Odontology - February 16, 2023 Category: Dentistry Source Type: research
The anti-adherence activity and bactericidal effect of GO against Streptococcus mutans from Iraqi dental patients
AbstractThe high rate of microbes and their biological activity in the patient ’s mouth is a concern in the domains of dental caries and periodontal disease. The study aimed to shed light on the relationship between graphene oxide’s nanoparticles (nGOs) antimicrobial properties and the growth of dental pathogenic bacteria. The forty swab samples were frequently collected f rom the patient’s cavity mouth between November 2019 and January 2020, from patients who visited dentist clinics in Baghdad by taking swabs from mouth cavities with various dental caries with two age groups (5–17) and (18–60) from male and fema...
Source: Odontology - February 15, 2023 Category: Dentistry Source Type: research
Endoscopic visualization of the inferior alveolar nerve associated with somatosensory changes after impacted mandibular third molar extraction
In conclusion, it was found that not all exposed IAN in CBCT images were real exposure after surgery. The intraoperative e xposed IAN endoscopic measurements were smaller than by CBCT and strongly correlated with some QST parameters. (Source: Odontology)
Source: Odontology - February 11, 2023 Category: Dentistry Source Type: research
β-defensin 2 synthesized by a cell-free protein synthesis system and encapsulated in liposomes inhibits adhesion of Porphyromonas gingivalis to oral epithelial cells
Abstractβ-defensin 2 (BD-2), an antimicrobial peptide (AMP), is expressed by oral epithelial cells and plays an important role in innate immunity of the oral cavity. Cell-free protein synthesis (CFPS) systems have been studied for the synthesis of various proteins, however, the synthesis of BD-2 by a CFPS system has not been extensively explored. Liposomes have been developed as tools for drug delivery. A delivery of liposome-encapsulated AMP to oral epithelium may be useful to prevent oral infectious diseases. In the present study, we investigated the antimicrobial activity of the BD-2 protein, arti ficially synthesized ...
Source: Odontology - February 6, 2023 Category: Dentistry Source Type: research
Development and validation of a method for creating incomplete vertical root fracture in extracted teeth
AbstractThe present study reported a method for inducing incomplete root fracture in human extracted teeth for the purpose of evaluating the merits of different diagnostic imaging techniques. Thirty-five single-rooted teeth were inspected under magnification and transillumination to exclude previously fractured teeth. Tooth crowns were removed, and the root canals were prepared up to the ProTaper Next X4 (40.06) file. Each root was lined with wax and embedded in a polystyrene resin block. The setup was attached to a universal testing machine for pressing a customized conical wedge (diameter at tip: 0.6 mm; taper: 0.2 mm...
Source: Odontology - January 28, 2023 Category: Dentistry Source Type: research
