Physicochemical and mechanical properties of preheated composite resins for luting ceramic laminates
This study analyzed and compared the physicochemical and mechanical properties of preheated resin composite with light-cured resin cement for luting indirect restorations. 210 specimens of resin cement/resin composite were prepared according to preheating treatment heated (Htd) or not (NHtd). Light-cured resin cement (Variolink Veneer, Ivoclar), and resin composite (Microhybrid —Z100, 3 M; Nanohybrid—Empress direct, Ivoclar; and Bulk fill–Filtek One, 3 M) were used (n = 10). Resin cement specimens were not preheated. The response variables were (n = 10): film thickness, microhardness, liquid sorption and so...
Source: Odontology - February 2, 2024 Category: Dentistry Source Type: research
Fracture strength of endocrowns after thermomechanical aging
AbstractThis in-vitro study aimed to evaluate the fracture strength (FS; N) of composite, feldspathic, and glass –ceramic computer-aided design/computer-aided manufacturing (CAD/CAM) endocrowns after thermomechanical aging. Seventy non-carious human molars were randomly divided into seven groups, according to the CAD/CAM material used for endocrown fabrication. Intact molars without cavity preparations were used as control (n = 10). Following endodontic treatment, standardized endocrown cavities were prepared and endocrowns were fabricated using composite (Cerasmart270, CS and Grandio Blocs, GB), fired and milled zir...
Source: Odontology - January 30, 2024 Category: Dentistry Source Type: research
The effect of the enzymes trypsin and DNase I on the antimicrobial efficiency of root canal irrigation solutions
AbstractThe purpose of this study was to evaluate the antibacterial efficacy of using 2.5% NaOCl, 2% chlorhexidine (CHX), Irritrol, and chitosan-coated silver nanoparticles (AgCNPs) alone or in combination with deoxyribonuclease I (DNase I) and trypsin pre-enzyme applications in dentin samples contaminated withEnterococcus faecalis (E. faecalis) by CLSM. 144 dentin blocks with confirmedE. faecalis biofilm formation were divided randomly according to the irrigation protocol (n = 12): NaOCl, CHX, Irritrol, AgCNPs, trypsin before NaOCl, CHX, Irritrol, AgCNPs, and DNase I before NaOCl, CHX, Irritrol, AgCNPs. Dentin blocks ...
Source: Odontology - January 27, 2024 Category: Dentistry Source Type: research
Evaluation of the antimicrobial efficacy of different nonsteroidal anti-inflammatory drugs alone or in combination with calcium hydroxide intracanal medicament: an in vitro study
This study explored the antimicrobial effects of ketoprofen, piroxicam, and celecoxib alone or combined with calcium hydroxide (CH) against two strains ofEnterococcus faecalis (E. faecalis) and assessed the influence of such combinations on the pH of CH. Minimum inhibitory concentrations (MICs) of the three tested NSAIDs were determined. Tested pastes were placed into wells punched in seeded agar plates and the bacterial inhibition zones were measured. Antibiofilm activity was assessed against 3 weeks of biofilm induced in bovine dentine blocks. The pH of the pastes was measured at four-time intervals. MIC values were 3.12...
Source: Odontology - January 24, 2024 Category: Dentistry Source Type: research
Relationship of MMP-9 with the clinical course of apical periodontitis and the main bacterial species in the oral microbiota
This study aimed to determine the main bacterial species in the microbiota as gram positive and negative and to compare the relationship between matrix metalloproteinase (MMP)-9 and tumor necrosis factor (TNF)- α with controlled patient groups. 60 patients with AP and extraction indication were included in the study. 30 systemically healthy volunteers without AP were selected as the control group. After access cavity preparation, an initial microbiologic sample (S1) was taken from the root canal. After at raumatic extraction of the tooth, a second microbial sample (S2) was taken from the extraradicular region. After bacte...
Source: Odontology - January 22, 2024 Category: Dentistry Source Type: research
Reducing apical voids for intra-canal sealer injection using a modified passive deflation needle
AbstractThe aim of the study was to evaluate the ability of a modified passive deflation needle to reduce the apical voids during the intra-canal iRoot SP sealer injection. A modified passive deflation injection needle was designed. Forty 20 °-curved and twenty S-shaped single-canal resin block models were allocated into six groups. Each group was mechanically prepared to #25/04 or #25/06 file; then the root canals were injected with iRoot SP sealer using a modified needle or a normal plastic needle. Radiographs were taken to measure t he length of apical void in each specimen. Similarly, twenty single-canal extracted pre...
Source: Odontology - January 20, 2024 Category: Dentistry Source Type: research
Adiponectin inhibits ROS/NLRP3 inflammatory pathway through FOXO3A to ameliorate oral submucosal fibrosis
In conclusion, APN ameliorated arecoline-induced OSF by promoting FOXO3A expression and downregulating the ROS/NLRP3 pathway. (Source: Odontology)
Source: Odontology - January 13, 2024 Category: Dentistry Source Type: research
Aberrated PSMA1 expression associated with clinicopathological features and prognosis in oral squamous cell carcinoma
AbstractOral squamous cell carcinoma (OSCC) is a globally prevalent cancer with significant mortality rates. OSCC a predominant subtype of head and neck squamous cell carcinoma (HNSCC), poses a substantial health burden. Despite advancements in diagnosis and therapy, OSCC prognosis remains poor. The 26S proteasome, a cellular protein degradation complex, is associated with cancer, including PSMA1, a proteasomal subunit, which is upregulated in various cancers. We analyzed PSMA1 expression using TCGA data, validated it in OSCC samples using real-time PCR, and explored its role through various databases. Tumor and adjacent n...
Source: Odontology - January 12, 2024 Category: Dentistry Source Type: research
Influence of the metal post material, tooth location in the dental arch, and metal artifact reduction tool on vertical root fracture diagnosis in cone beam CT
This study aimed to evaluate the influence of the metal post composition, tooth location in the dental arch, and metal artifact reduction (MAR) on vertical root fracture (VRF) diagnosis in cone beam computed tomography (CBCT). Twenty-two unirradicular premolars (12 sound and 10 fractured) and two alveolar sockets of a mandible (anterior and posterior regions) composed the sample. CBCT scans of each tooth with a metal post placed into the root canal —silver–palladium (Ag–Pd), cobalt–chromium (Co–Cr), or nickel–chromium (Ni–Cr)—were individually acquired for each mandibular region, and two conditions of MAR, ...
Source: Odontology - January 12, 2024 Category: Dentistry Source Type: research
Long-lasting adverse effects of short-term stress during the suckling –mastication transition period on masticatory function and intraoral sensation in rats
In conclusion, short-term early-life stress during the suckling –mastication transition period potentially causes a persistent decrease in masticatory ability and intraoral hypersensitivity in adulthood. The period is a “critical window” for the maturation of oral motor and sensory functions. (Source: Odontology)
Source: Odontology - January 10, 2024 Category: Dentistry Source Type: research
Effects of mineral trioxide aggregate and methyl sulfonyl methane on pulp exposure via RUNX2 and RANKL pathways
AbstractThe aim of this study was to determine the therapeutic effects of mineral trioxide aggregate (MTA) and methyl sulfonyl methane (MSM) on pulp damage due to pulp exposure through the RUNX2 and RANKL pathways. Seventy-two male Sprague-Dawley rats aged 4 –6 months and weighing 250–300 g were divided into healthy, control, MTA, and MSM groups. After experimental applications, all rats at 2, 4, and 8 weeks were killed anesthetically with xylazine hydrochloride (Rompun, Bayer) 30 mg/kg and ketamine hydrochloride (Ketalar, Pfizer) 50 mg/kg injec tions (i.p.). We observed that necrotic odontoblasts, edema, inflammat...
Source: Odontology - January 9, 2024 Category: Dentistry Source Type: research
Ultrasonic activation of the endodontic sealer enhances its intratubular penetration and bond strength to irradiated root dentin
AbstractTo evaluate the effect of ultrasonic activation of the endodontic sealer on its intratubular penetration and bond strength to irradiated root dentin. Forty human teeth were distributed into 4 groups (n = 10), according to the radiation therapy (RT) exposure—70 Gy—and ultrasonic activation (UA) of the endodontic sealer: RT/UA—irradiated teeth and sealer UA; RT/no-UA—irradiated teeth and no sealer UA; no-RT/UA—non-irradiated teeth and sealer UA and no-RT/no-UA—non-irradiated teeth and no sealer UA. Push-out bond strength test was performed in a Universal Testing Machine. Failure modes and adhesive in...
Source: Odontology - January 9, 2024 Category: Dentistry Source Type: research
Finite element evaluation of dentin stress changes following different endodontic surgical approaches
AbstractThe aim was to compare the effect of different endodontic surgical treatments on the stress distributions in dentin of a simulated first mandibular molar tooth using the finite element analysis method. Three surgical endodontic procedures (apical resection, root amputation, and hemisection) were simulated in a first mandibular molar. Biodentine or mineral-trioxide-aggregate was used to repair the surgery site in apical resection and root amputation models; the remaining root canal spaces were filled with gutta-percha. Access cavities were restored using resin composite. In hemisection model, root canal was filled w...
Source: Odontology - January 6, 2024 Category: Dentistry Source Type: research
A mechanical and three-dimensional finite element study of the optimum tooth sectioning depth during the extraction of low-level horizontally impacted mandibular third molar
AbstractThe present study aims to determine the optimum sectioning depth for the extraction of low-level horizontally impacted mandibular third molar (LHIM3M) using mechanical and finite element analysis. One hundred and fifty extracted mandibular third molars were randomly divided into three groups: 1, 2 or 3 mm of tooth tissue was retained at the bottom of the crown. The breaking force of teeth was tested in a universal strength testing machine. The fracture surface was observed and the type of tooth breakage was recorded. According to the three groups, corresponding 3D finite element models were crea ted. The breaking...
Source: Odontology - January 1, 2024 Category: Dentistry Source Type: research
Examination of age-related changes in the submandibular glands of male mice
AbstractSalivary gland hypofunction adversely affects the oral environment and daily life by causing dry mouth (xerostomia). Senescence-related atrophy of salivary gland tissues is one cause of xerostomia, and it is particularly common among the elderly. However, the underlying mechanism is poorly understood, and no treatment has been established. Therefore, we examined age-related changes in senescence-associated secretory phenotype (SASP) factors, which regulate stemness and cellular senescence, in mouse submandibular glands. We analyzed the submandibular glands of 6-week-old (young group,n = 6) and 82-week-old mice ...
Source: Odontology - January 1, 2024 Category: Dentistry Source Type: research
