Irrigant flow characteristics in the root canal with internal root resorption: a computational fluid dynamics evaluation
AbstractIrrigation dynamics of syringe irrigation with different needle designs (side-vented, double side-vented, notched) and ultrasonic irrigation in the root canal with internal root resorption were evaluated using a computational fluid dynamics model. A micro-CT scanned mandibular premolar was used for modeling internal root resorption. The needles and the ultrasonic tip were positioned at 2, 4, and 5  mm from the working length. The insertion depth and the irrigation model were found influential on the shear stress and the irrigant extension. The extension of the irrigant increased toward 2–5 mm from the working l...
Source: Odontology - February 26, 2022 Category: Dentistry Source Type: research

Comparison of antimicrobial and wound-healing effects of silver nanoparticle and chlorhexidine mouthwashes: an in vivo study in rabbits
The objective is to formulate a silver nanoparticle mouthwash and then evaluate its antimicrobial and wound-healing effects in rabbit animal models. Microbial samples were collected from the oral cavity of 60 rabbits. Thereafter, standardized wounds were created in the lateral border of the tongue on the right side for all rabbits. After surgery, digital photographs were obtained from the wounds with standardized settings. To characterize the silver nanoparticles used in the synthetic mouthwash, transmission electron microscopy (TEM) and digital light scattering analysis were used. The animal models were then randomly divi...
Source: Odontology - February 26, 2022 Category: Dentistry Source Type: research

Evaluation of accuracy and characteristics of tooth-color matching by intraoral scanners based on Munsell color system: an in vivo study
AbstractTo compare the accuracy of visual and instrumental methods for tooth-color matching based on three attributes in the Munsell color system and to investigate the characteristics of intraoral scanners for tooth-color matching. Shades of the cervical, middle, and incisal third region of 130 maxillary anterior teeth were matched visually by an experienced prosthodontist (EP) using Vita classical A1-D4 (VC) and Vita System  3D-Master (V3D) shade guides, and digitally by a spectrophotometer (Vita Easyshade V, VE) and two intraoral scanners (3Shape TRIOS 3, T3; TRIOS 4, T4). VE was used as a reference. The reproducibilit...
Source: Odontology - February 25, 2022 Category: Dentistry Source Type: research

Interleukin-1 β regulates odontogenic ameloblast-associated protein gene transcription in human gingival epithelial cells
AbstractJunction epithelium (JE) is located apical to the bottom of the gingival sulcus and binds enamel to hemidesmosomes to protect the periodontal tissue from bacterial infection. Function of odontogenic ameloblast-associated protein (ODAM) is suggested by its expression sites (JE and maturation stage ameloblasts) to be involved in the adhesion between the JE and enamel, and odontogenesis. To analyze the changes in ODAM gene and protein expressions in inflamed gingiva, Ca9-22 gingival epithelial cells were stimulated with 1  ng/ml interleukin-1β (IL-1β) for 3–24 h, and ODAM mRNA and protein levels were analyzed by...
Source: Odontology - February 18, 2022 Category: Dentistry Source Type: research

Correction to: The effect of functionalized titanium dioxide nanotube reinforcement on the water sorption and water solubility properties of flowable bulk-fill composite resins
(Source: Odontology)
Source: Odontology - February 17, 2022 Category: Dentistry Source Type: research

Bevacizumab and sunitinib mediate osteogenic and pro-inflammatory molecular changes in primary human alveolar osteoblasts in vitro
AbstractAntiangiogenic medications target the de novo blood vessel formation in tumorigenesis. However, these novel drugs have been linked to the onset of medication-related osteonecrosis of the jaw (MRONJ). The aim of this in vitro study was to examine the effects of the vascular endothelial growth factor A (VEGFA) antibody bevacizumab (BEV) and the receptor tyrosine kinase inhibitor (RTKI) sunitinib (SUN) on primary human osteoblasts derived from the alveolar bone. Primary human alveolar osteoblasts (HAOBs) were treated with BEV or SUN for 48  h. Cellular metabolic activity was examined by XTT assay. Differentially regu...
Source: Odontology - February 16, 2022 Category: Dentistry Source Type: research

The power of weak ion-exchange resins assisted by amelogenin for natural remineralization of dental enamel: an in vitro study
This study aims to develop an innovative dental product to remineralize dental enamel by a proper combination of ion-exchange resins as controlled release of mineral ions that form dental enamel, in the presence of amelogenin to guide the appropriate crystal growth. The novel product proposed consists of a combination of ion-exchange resins (weak acid and weak base) individually loaded with the remineralizing ions: Ca2+, PO43 − and F−, also including Zn2+ in a minor amount as antibacterial, together with the protein amelogenin. Such cocktail provides onsite controlled release of the ions necessary for enamel reminerali...
Source: Odontology - February 11, 2022 Category: Dentistry Source Type: research

Correlations between additional roots in maxillary second molars, maxillary first premolars, mandibular first molars and mandibular first premolars: a retrospective cone-beam computed tomography analysis
This study aimed to determine the prevalence of additional roots in maxillary second molar (MSM), maxillary first premolar (MxFP), mandibular first molar (MnFM) and mandibular first premolar (MnFP) teeth and evaluate the correlations between the number of roots for these teeth. Images of 630 Turkish patients, in which all dental groups examined in the study were present bilaterally, were analyzed using cone-beam computed tomography. The images for the presence of the fourth root in MSMs, third root in MxFPs, distolingual root in MnFMs and complicated-root structure in MnFPs were assessed and divided additional roots into s...
Source: Odontology - January 31, 2022 Category: Dentistry Source Type: research

Direct and semi-direct resin composite restoration in large cavity preparations: analysis of dentin bond strength stability and bottom/top microhardness ratio in a cavity model
AbstractTo evaluate the influence of the restorative approach and aging time on dentin bond strength (BS), failure mode (FM), and bottom/top microhardness ratio (B/T) in a large dentin cavity model. A total of 102 bovine incisors were used to produce models of conical dentin cavities (4.0  mm thickness × 4.8 mm top diameter × 2.8 mm bottom diameter), which were restored using semi-direct filling (SDF) (Filtek™ Z250 XT + Scotchbond™ Universal/RelyX™ Ultimate luting system), direct bulk filling (DBF) (Filtek™ One Bulk Fill), and direct incremental filling (DIF) (Filtek™ Z250 XT) techniques. B/T, BS...
Source: Odontology - January 28, 2022 Category: Dentistry Source Type: research

Fracture resistance of root canal-treated molars restored with ceramic overlays with/without different resin composite base materials:  an in vitro study
The objective of the study was to evaluate the effect of different restorative protocols on fracture resistance of root canal-treated molars. 48 mandibular first molars were used and divided into six groups (n  =  8); G1 (negative control): teeth kept intact. G2 (positive control): teeth had root canal treatment and standard MOD cavity preparations but kept unrestored. G3: prepared as G2 and directly restored with VitaEnamic ceramic overlays (CO). G4: as G3, but the pulp chamber was restored first with sma rt dental restorative (SureFil SDR flow = SDR) bulk-fill flowable composite base. G5: as G3, but the pulp cham...
Source: Odontology - January 22, 2022 Category: Dentistry Source Type: research

Experimental study on the biocompatibility and osteogenesis induction ability of PLLA/DDM scaffolds
AbstractTo investigate the characterization and function of a novel porous osteogenic material (PLLA / DDM) containing polylactic acid and demineralized dentin matrix. The surface morphology and composition of the material were observed by SEM and EDS. The physical characteristics of the material were detected by roughness and water contact angle analyses. The rate of weight loss and change in the pH value of the material were observed by scaffold degradation experiments. Four types of material were investigated: polylactic acid (PLLA) scaffold, demineralized dentin matrix (DDM) particles, PLLA/DDM scaffold and a blank con...
Source: Odontology - January 20, 2022 Category: Dentistry Source Type: research

Effect of root perforation repair with mineral aggregate-based cements on the retention of customized fiberglass posts
AbstractThe purpose of this study was to investigate whether the root perforation repair with mineral aggregate-based cements affects the retention of customized fiberglass posts to bovine intraradicular dentin. Sixty-four bovine mandibular incisors had their root canals endodontically treated and prepared for fiberglass posts luting. Teeth were randomly distributed into four groups (n = 16), according to the cement used for the perforations repair (MTA HP; calcium aluminate cement—CAC; and CAC + calcium carbonate nanoparticles—nano-CaCO3) and control group (no perforation). The groups were redistributed accord...
Source: Odontology - January 19, 2022 Category: Dentistry Source Type: research

Strontium ranelate improves post-extraction socket healing in rats submitted to the administration of bisphosphonates
AbstractThe aim of this study was to evaluate the effect of strontium ranelate (Sr) on post-extraction socket healing in rats submitted to the administration of bisphosphonates. Sixty rats were submitted to the tooth extraction of the first lower molar after 60  days of the daily administration of saline solution (SS) or alendronate (ALN). Then, the animals were allocated into six groups namely CTR: administration of SS during the whole experiment, ALN: administration of ALN during the whole experiment, ALN/SS: application of SS for 30 days after extract ion in animals previously treated with ALN, ALN/Sr: application of ...
Source: Odontology - January 18, 2022 Category: Dentistry Source Type: research

Effect of stain brand and shade on color stability of stains applied on a CAD-CAM feldspathic ceramic
AbstractThe aim of this study was to investigate the effect of stain brand and color on color stability of stains on a CAD-CAM ceramic after aging. Specimens (15  × 8 × 1.5 mm) were fabricated from A2-shade ceramic blocks (Mark II; Vita Zahnfabrik) (N = 120). Specimens were divided into two groups (n = 10) to be stained with six different stains (yellow, orange, blue, gray, violet, and brown) from two manufacturers (GC initial spectrum (GC) and IPS e.max Ceram (IPS)). Aging was performed for 5 h at 134 °C. Color coordinates before and after aging were measured to calculate color differen ces (ΔE00). ...
Source: Odontology - January 18, 2022 Category: Dentistry Source Type: research

Self-ligating brackets exhibit accumulation of high levels of periodontopathogens in gingival crevicular fluid
AbstractDifferent types of brackets seem to influence the disruption of the oral microbial environment. Therefore, the aim of this study was to evaluate the influence of self-ligating brackets on the gingival crevicular fluid levels of the putative periodontal pathogensAggregatibacter actinomycetemcomitans sorotype a (Aaa), Tannerella forsythia, Fusobacterium nucleatum, andPorphyromonas gingivalis. Sixty samples of crevicular fluid of twenty patients (11 boys and 9 girls) were analysed at baseline (T0) and after 30 (T1) and 60 (T2) days of bonding of the self-ligating (In-Ovation®R, Dentsply, GAC or SmartClip ™, 3 M Un...
Source: Odontology - January 17, 2022 Category: Dentistry Source Type: research